The Doctor's Farmacy With Mark Hyman, M.d.

Cory Richards has summited Everest without oxygen, survived avalanches, and photographed some of the world’s most remote regions. But his most grueling expeditions didn’t happen on a mountain—they happened within. In this revealing episode of The Dr. Hyman Show, you’ll hear how a life shaped by mental health struggles, institutionalization, and homelessness led Cory to push the limits of endurance—and how those experiences can offer powerful lessons on healing and self-discovery. We explore: • Why big achievements don’t guarantee fulfillment—and what actually does • How spending time in nature and solitude can help you reconnect with yourself and find clarity • What Cory’s journey through trauma and recovery can teach you about your own capacity to heal • Why creativity, purpose, and self-reflection are essential tools for building a meaningful life Don’t miss this powerful conversation about what it really takes to overcome adversity. View Show Notes From This EpisodeGet Free Weekly Health Tips from

Cutting-edge medical advances are unlocking new ways to slow aging and enhance health. Plasmapheresis removes harmful inflammatory molecules, toxins, and cellular waste from plasma, helping to reduce biological aging and improve resilience. Muse cells, a powerful form of stem cell therapy, show promise in regenerating tissue and treating complex conditions like ALS and stroke. And peptides—small, naturally occurring signaling molecules—support healing, immune balance, and cellular repair, offering practical tools for longevity and optimized health. In this episode, I talk with Dr. Darshan Shah, Dr. Adeel Khan, and Dr. Edwin Lee about medical advancements that are the ultimate longevity biohacks. Dr. Darshan Shah is a board-certified surgeon, longevity medicine expert, author, and founder of Next Health—the world’s largest Health Optimization and Longevity clinic. He has performed over 20,000 surgical procedures and advised thousands on extending healthspan and lifespan. A prodigy in medicine, Dr. Shah earne

Who in the world would try to lower their cholesterol by eating an entire sleeve of Oreos every day for a month? Meet Nick Norwitz, PhD, an Oxford graduate and Harvard medical student who did just that—in an effort to test a hypothesis about cholesterol and metabolic health. After reversing a serious inflammatory condition with a ketogenic diet, Nick saw his LDL cholesterol spike. Instead of panicking, he turned to research—and self-experimentation—to better understand what those numbers really meant. In this episode of The Dr. Hyman Show, we explore: • The health crisis that led Nick to a ketogenic diet • Why his LDL cholesterol jumped—and what questions it raised • The Oreo experiment and what it did (and didn’t) reveal • The nuance around LDL, metabolic health, and cardiovascular risk • What the science—and Nick’s own experience—suggests about meat, veganism, and finding a diet that works Check out the episode to hear this fascinating conversation.  View Show Notes From This EpisodeGet Free Weekly

There has been a fundamental shift in understanding metabolic health and chronic disease, particularly Type 2 diabetes, challenging long-standing dietary dogma by emphasizing that insulin resistance is largely driven by overconsumption of refined carbohydrates, not dietary fat or red meat. While highlighting the success of carbohydrate restriction and ketogenic approaches, nutrition is being seen as a powerful tool for reversing diabetes—often more effective and sustainable than conventional medication. The implications are far-reaching, not only for individual health outcomes, but also for reshaping public health strategies in addressing today’s chronic disease epidemic. In this episode, I speak with Gary Taubes, Sami Inkinen, and Dr. Greeshma Shetty about an approach to treating Type 2 Diabetes that works. I also discuss how red meat is not to blame, but we should be looking at high sugar and starch diets. Gary Taubes is an award-winning science and health journalist, and co-founder and director of the Nu

We all know emotional maturity is essential for a healthy relationship—but how do you actually get there? In this episode of The Dr. Hyman Show, I talk with Diego Perez, the #1 New York Times bestselling author known as Yung Pueblo, about the small mindset shifts that can make a huge difference in how you show up for yourself and your partner. Drawing from his new book, How to Love Better, Diego shares how to stop repeating the same old patterns and start building relationships grounded in awareness, honesty, and real emotional growth. In this conversation, we explore: Why emotional maturity is the #1 skill for resolving conflict How letting go of control can lead to more trust, connection, and ease in your relationship How your old emotional patterns might be causing tension you don’t even realize Why owning your emotions can help you avoid blame and grow together Simple mindset shifts that can make love feel more secure, stable, and honest Check out the episode for a practical, compassionate guide

Many people struggle with mysterious symptoms like fatigue, brain fog, food sensitivities, and skin issues—only to be misdiagnosed or dismissed altogether. This conversation highlights how histamine intolerance and mast cell activation syndrome can be the hidden drivers behind a wide range of chronic conditions, and why they're often overlooked in conventional medicine. From the role of gut health, food triggers, and environmental toxins to deeper root causes like Lyme disease or mold exposure, it’s clear that personalized, Functional Medicine is key to uncovering real answers. Understanding the immune system’s role in histamine reactions—and how even “healthy” foods can be inflammatory for some—is a critical step toward healing. In this episode, I talk with Dr. Todd LePine, Dr. Elizabeth Boham, and Dr. Mark Pimentel about what histamine intolerance is, how it can be related to gut health, and why it’s important to address it. Dr. Todd LePine graduated from Dartmouth Medical School and is Board Certified in

Ultra-processed food is the new cigarette—and it's fueling a global health crisis hiding in plain sight. In today’s episode, I’m joined by Dr. Chris van Tulleken—infectious disease physician, BBC broadcaster, and author of Ultra-Processed People—to expose the truth behind ultra-processed foods and the industries driving their consumption. To find out what this food is really doing to us, Dr. van Tulleken became the first subject in a groundbreaking clinical trial—eating 80% of his calories from ultra-processed food for a full month. We unpack what makes ultra-processed food fundamentally different from real food—even when the ingredients look similar, and why its impact on your brain, metabolism, and long-term health is far worse than anyone thought… You’ll learn: How ultra-processed food hijacks your brain’s reward system The science behind food addiction and satiety hormones Why food labels and front-of-package claims are designed to mislead you What the latest data says about UPFs and 32 chronic diseas

Sleep is not just a luxury—it’s a foundational pillar of health that influences nearly every aspect of our well-being. Sleep deprivation doesn’t just cause fatigue; it disrupts hormones, drives inflammation, damages metabolism, and accelerates aging. From the gut microbiome to stress hormones like cortisol, sleep is deeply intertwined with brain, immune, and metabolic health. Yet our modern world—filled with late-night screens, ultra-processed foods, and chronic stress—works against quality rest.  In this episode, I discuss, along with Dr. Matt Walker and Shawn Stevenson, why we need to address sleep as a core health priority to unlock healing, prevention of chronic disease, and renewed vitality. Matthew Walker earned his PhD in neuroscience from the Medical Research Council in the UK, and subsequently became a Professor of Psychiatry at Harvard Medical School. He is currently a Professor of Neuroscience and Psychology at the University of California, Berkeley, and director of the Center for Human Sleep Scien

Are U.S. food companies cutting corners at the expense of your health? Vani Hari, known to many as the Food Babe, thinks so—and she’s spent over a decade sounding the alarm. In this episode of The Dr. Hyman Show, she shares why she believes many American products are still made with harmful additives and dyes, even though companies have found ways to remove them in versions sold abroad. In our conversation, she explains: Why she believes Kellogg’s and other U.S. brands aren’t doing enough to protect American consumers. The FDA loophole she says allows companies to self-approve food chemicals without oversight. How food dyes could be contributing to rising rates of behavioral issues in kids. The labeling gaps and industry tactics she says are keeping consumers in the dark. How everyday people can push back—and why she believes activism still works. Don’t miss this insightful episode! View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign

What if your fatigue, weight gain, hormone imbalances, and brain fog all traced back to a silent disease that affects 1 in 3 people—and you didn’t even know you had it? In today’s episode, I’m joined by Dr. Elizabeth Boham and Dr. Yousef Elyaman to talk about a condition that’s quietly becoming one of the biggest threats to our health: fatty liver disease—now renamed Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). It’s not just a liver issue. It’s deeply connected to heart disease, cancer, infertility, type 2 diabetes, dementia, and even hormone dysfunction. The most alarming part is it’s often missed in traditional medicine because there’s no easy drug to prescribe. We break down: The real root causes—from sugar and starch overload to gut imbalances, toxins, alcohol, and chronic inflammation The surprising early warning signs your body might be giving you Why standard labs often miss it, and the tests you actually need The step-by-step functional medicine approach to reverse fatty live

We’re overfed, but undernourished. Despite having access to more food than ever, most people are walking around with nutrient deficiencies that could be accelerating aging, increasing disease risk, and depleting energy levels. That’s why I sat down with Dr. Rhonda Patrick, a leading expert in nutritional science and aging, to break down what we’re missing—and why it matters. In this episode of The Dr. Hyman Show, we explore: Why nearly 70% of Americans are deficient in vitamin D and what that means for longevity. The overlooked role of magnesium in metabolism, blood sugar, and brain function. Why our food system leaves us malnourished—even if we eat a “healthy” diet. The best way to assess and correct micronutrient imbalances for optimal health. Your body can’t function properly without the right nutrients. This episode will show you how to fill the gaps and take control of your health. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevi

Fertility challenges are increasingly linked to lifestyle and environmental factors that go far beyond reproductive organs. Emerging science reveals that metabolic health, inflammation, diet, and exposure to environmental toxins all play a profound role in hormonal balance, egg and sperm quality, and even early embryo development. Key drivers of dysfunction—such as ultra-processed food, insulin resistance, gut imbalances, and mitochondrial damage—are rarely addressed in conventional fertility care, despite their deep impact. Paying attention to these overlooked root causes offers not only a powerful path to improving fertility but also the foundation for lifelong health in both parents and their future children. In this episode, I discuss, along with Kelly LeVeque, what we can do to improve our fertility, which ultimately impacts the future health of our children. Kelly LeVeque is a holistic nutritionist, celebrity health coach, the best-selling author of Body Love and Body Love Every Day, and most importan

What if the key to aging well had been hiding in plain sight—inside our cells, our food, and even… dolphins? That’s exactly what Stephanie Venn-Watson, DVM, a veterinary epidemiologist, discovered while studying dolphins in the U.S. Navy’s marine mammal program. She found that some dolphins were aging significantly slower than others, leading to the discovery of C15:0—a newly recognized essential fatty acid that supports cellular health, fights inflammation, and may even slow the aging process. In this episode of The Dr. Hyman Show, we dive into: How studying dolphins led to the discovery of C15:0 as the first essential fatty acid found in 90 years. Why a deficiency in this nutrient could be accelerating aging and chronic disease. How C15:0 strengthens cell membranes, reduces inflammation, and promotes longevity. The connection between diet, metabolic health, and optimal aging. What you can do to ensure you’re getting enough of this essential fatty acid. This groundbreaking discovery could change how we

The connection between mental health and metabolic health is far deeper than once believed, with growing evidence showing a powerful, bidirectional relationship. Inflammation, poor diet, and gut dysfunction are now recognized as key drivers of both physical and psychological illness—often hiding in plain sight. By addressing root causes such as blood sugar imbalances, nutritional deficiencies, and microbiome disruption, many chronic mental health conditions can improve or even resolve. This emerging science challenges the traditional separation of mind and body, pointing instead to an integrated approach where healing the body becomes essential for healing the brain. Recognizing this link is crucial in shifting the future of mental health care. In this episode, I discuss, along with Dr. Chris Palmer and Dr. Shebani Sethi, why our diet is so closely related to the state of our mental health. Dr. Chris Palmer is a psychiatrist and researcher working at the interface of metabolism and mental health. He is the Di

You probably know Ian Somerhalder from The Vampire Diaries or Lost, but these days, he’s on a mission far bigger than Hollywood. Ian has dedicated his time and platform to tackling some of the most pressing issues of our time—our broken food system, soil depletion, and the health crisis caused by industrial agriculture. In this episode of The Dr. Hyman Show, we explore: How Ian’s passion for regenerative agriculture was shaped by his childhood and family history. The alarming impact of pesticides on human health and the environment. Why farmers are stuck in a toxic cycle—and how regenerative farming offers a way out. How shifting just 10% of U.S. farmland to regenerative practices could transform our health and economy. The powerful connection between soil health, gut health, and disease prevention. Ian’s journey proves that real change starts with what’s on our plates. Don’t miss this inspiring conversation. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. H

The pervasive presence of microplastics and environmental toxins in our daily lives poses a growing threat to human health, with impacts ranging from hormonal disruption and metabolic dysfunction to immune system compromise and chronic inflammation. These contaminants, found in food packaging, water supplies, personal care products, and even the air we breathe, accumulate in the body and contribute to the rise in chronic diseases such as obesity, diabetes, cancer, and autoimmune conditions. Understanding their far-reaching effects is essential, but the good news is that the body has powerful detoxification mechanisms that, when properly supported through dietary choices, lifestyle adjustments, and targeted supplementation, can help mitigate their damage.  In this episode, I discuss, along with toxin-expert Dr. Joseph Pizzorno, why we need to take action to reduce toxin exposures, reverse existing damage, and build a foundation for long-term well-being. Dr. Joseph Pizzorno is a transformational leader in medic

What if I told you life insurance companies can predict, almost to the month, when you’re going to die? That’s exactly what Gary Brecka, a human biologist and former mortality expert, used to do—until he uncovered something shocking. After years of analyzing blood work and medical records, he realized that the biggest predictors of disease and early death aren’t genetic—they’re modifiable. Now, he’s using that knowledge to help people optimize their health and extend their lifespan. In this episode of The Dr. Hyman Show, we discuss: How insurance companies use hidden health data to predict life expectancy with stunning accuracy. The biggest factors that shorten lifespan—and why most of them are within our control. Why vitamin deficiencies, especially vitamin D, are quietly fueling chronic disease. How the right biohacking tools, like red light therapy and oxygen optimization, can reverse aging. What you can do today to take control of your health and longevity. This conversation will change the way you

Our immune system operates like a finely tuned symphony, yet many of us find ourselves out of harmony, vulnerable to persistent infections, autoimmune conditions, and chronic disease. Rather than merely suppressing symptoms, a Functional Medicine approach seeks to identify and address the underlying disruptions driving immune imbalance. Central to this dysfunction is compromised gut health, which undermines immune regulation, while mitochondrial impairment and chronic inflammation further erode the body's capacity for resilience and repair. By restoring balance at the root level, we can cultivate a more robust and adaptive immune system. In this episode, I discuss, along with Dr. Elroy Vojdani and Dr. Leonard Calabrese, how cleaning up our diets, improving gut health, removing toxins, and decreasing stress can do wonders for our immune systems. Dr. Elroy Vojdani is a pioneer in the field of functional medicine and research and is the founder of Regenera Medical, a concierge functional medicine practice in Los

The modern food industry is built for profit, not health. Ultra-processed foods dominate grocery shelves, fueling the epidemic of obesity, diabetes, and chronic disease. But how did we get here? And what can we do to fix it? In this episode of The Dr. Hyman Show, I sit down with Michael Pollan, award-winning journalist and food activist, to break down the hidden forces shaping our food system and the urgent need for change. In this powerful conversation, you’ll discover: How a handful of corporations control our entire food supply—and why that’s a problem. The shocking truth about ultra-processed foods and how they’re engineered to keep you hooked. Why our food system collapsed during the pandemic and what it revealed about its fragility. How food companies quietly buy up health brands and use misleading labels to keep consumers in the dark. The role of policy and lobbying in keeping unhealthy food cheap and widely available. Make sure to tune in—this is a conversation every American needs to hear. Vi

With rates of Alzheimer’s and dementia rising steeply, especially among women, the conventional pharmaceutical model has largely failed in treating the brain. Functional Medicine takes a different systems-based, personalized approach—focusing on inflammation, metabolic health, and environmental exposures—which offers real hope for prevention and even reversal of cognitive decline. In this episode, I discuss, along with Dr. Heather Sandison, Dr. David Perlmutter, and Maria Shriver, why it is possible to reverse cognitive decline and the cutting-edge science of brain health and Alzheimer’s prevention. Dr. Heather Sandison is the The New York Times bestselling author of Reversing Alzheimer’s The New Toolkit to Improve Cognition and Protect Brain Health. As a renowned naturopathic doctor specializing in neurocognitive medicine, she’s the founder of Solcere Health Clinic, San Diego’s premier brain optimization clinic, and Marama, a residential program turning memory care into memory recovery. Dr. Sandison has dedi