Informações:
Synopsis
Cell (www.cell.com) is a peer-reviewed journal publishing the most interesting discoveries in biology.
Episodes
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August 2011: SUMOs in Gonad Development, Preserving Neural Stem Cells, and AML's Transformation Window
04/08/2011 Duration: 24minIn this month's Cell Podcast, we learn about how SUMOlyation wrestles hedgehog signaling into the right location during endocrine development, with Holly Ingraham (0:00), how neural stem cell progenitors are protected during starvation, from Alex Gould (12:01), and what's required in AML to make a cell susceptible to oncogenic transformation, explains Keith Humphries (17:48).
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July 2011: Parkinson's Disease, Human Height, and Polar Bears
07/07/2011 Duration: 21minIn this month's Cell Podcast, we learn about a lysosomal thread linking synucleinopathies, with Dimitri Krainc (0:00) (Mazzulli et al.), the genetics of human height, with Valerie Cormier-Daire (8:00), and polar bears: getting in touch with their surprising origins, with Beth Shapiro (14:31).
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June 2011: From Neural Stem Cells to Late-Night Snacking
09/06/2011 Duration: 32minIn this month's Cell Podcast, we learn about getting neural stem cells out of the lab and into the clinic, with Sally Temple (0:00), an important role for rare copy number variations in autism, with Matthew State and Michael Wigler (8:30), the dangers of midnight feasts for fruit fly fertility, with Amita Sehgal (18:04), and fitness costs and crosstalk in the evolution of host defense pathways, with Ruslan Medzhitov (24:32).
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May 2011: From Plasmodium to Plant Signaling
12/05/2011 Duration: 22minIn this month's Cell Podcast, we learn about ape droppings and the origins of malaria, with Julian Rayner (0:00), A next-gen sequencing technique to study high-speed gene expression, with W. Lee Kraus (9:35), and Tracing the evolution of signaling pathways in plants, with Alistair Hetherington (15:56).
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April 2011: HIV, Tuberculosis, and Cancer
14/04/2011 Duration: 21minIn this month's Cell Podcast, we learn about how HIV hides in hempatopoietic stem cells (0:00), combating tuberculosis drug resistance (7:25), and suppressing tumors with a protein isomerase (13:41).
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March 2011: Highlights from Recent Review Issues on Systems Biology and Addiction
17/03/2011 Duration: 24minCellular "coin-flipping;" Jim Collins explains how cells make decisions (0:00), the vicious cycle of treating drug addiction as a criminal behavior, instead of a medical condition (8:23), and how small molecules can help uncover signaling crosstalk, when genetic strategies fail (16:56).
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February 2011: From Cyanobacteria in Space to EPO's Immune-Modulatory Effects
24/02/2011 Duration: 23minEngineering cyanobacteria to a make a profit—not just biofuels (0:00), why breast cancers often metastasize to the bone (11:03), and EPO's surprising anti-inflammatory properties (17:15).
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January 2011: Aging: From Diagnosing Alzheimer's to Therapies for Progeria
20/01/2011 Duration: 24minHunting down biomarkers for Alzheimer's diease (0:30), modeling Progeria with iPS cells (10:13), and how yeast spare their daughter cells from toxic aging factors (16:52).
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December 2010: Human Genomics with a Dash of Chromatin Remodeling
09/12/2010 Duration: 27minHear about filling in the gaps of the 1000 genomes project (0:50), learn about tracking down an elusive culprit of inherited diseases. (10:05), discover how chromatin-modifying enzymes orchestrate skin development (18:22).
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November 2010: Osteoporosis, Pain Perception, and Tuberculosis Metabolomics
18/11/2010 Duration: 22minLearn how skeletal stem cells are key to improving osteoporosis treatment regimes (1.00), discover what a new pain gene has in common with Hungarian composer Franz Liszt (10.33), and hear insights from new metabolomics analysis of the tuberculosis pathogen (17:51).
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October 2010: Neurogenetics and cellular stress
21/10/2010 Duration: 32minHear how human genetics is transforming neuroscience (0:55), understand how sphingolipids are key signaling molecules during development(16:34), and learn about a critical interaction in noncanonical Wnt signaling (25:34).
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September 2010: The genetic basis of night blindness, microRNAs in regulatory T cells, and the mating habits of songbirds
23/09/2010 Duration: 19minLearn how a sodium-calcium exchanger helps humans see in the dark (0:42), understand why one microRNA is critical for stopping autoimmune attacks in mice (7:43), and hear how light pollution is coercing some songbirds to cheat on their mates (13:21).
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August 2010: Muscle wasting, gut regeneration, and brain metabolism
26/08/2010 Duration: 21minHear about a strategy to reverse the muscle wasting that accompanies cancer (00:55), learn about a kinase that is a key regulator of gut regeneration (07:42), and find out about new insights into brain metabolism (14:02).
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July 2010: Matrix metalloproteinases, functions of telomere DNA sequences, and fighting bacterial infections with diacyl glycerol
29/07/2010 Duration: 21minLearn how matrix metalloproteinases are involved in Huntington's disease (00:50), hear about the functions of telomere DNA sequences (9:46), and learn how the lipid diacyl glycerol helps to fight bacterial infection (16:13).
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June 2010: Reprogramming fibroblasts, Alzheimer's and autophagy, and neatly-folded DNA
23/06/2010 Duration: 24minLearn about a key step in the reprogramming of fibroblasts to induced pluripotent stem cells (00:49), hear about an unexpected connection between Alzheimer's disease and autophagy (10:44) and learn how our DNA stays neatly folded (18:44).
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May 2010: How the flu virus mobilizes immune cells, dendritic cells, and SAGA
26/05/2010 Duration: 22minHear how the influenza virus mobilizes immune cells, learn about the peripatetic habits of dendritic cells, and hear about the structure of a large transcription factor called SAGA.
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April 2010: Inhibiting the effects of ricin, type 1 diabetes, and brown fat
22/04/2010 Duration: 22minHear about two new inhibitors that block the toxin ricin, keep up to date with the latest research news about type 1 diabetes (10:13), and learn how brown fat can keep you thin (16.40).
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March 2010: Optogenetics tools, connecting social behaviour to neural circuitry, and addicted ovarian cancer cells
25/03/2010Hear how social behaviors are connected to neural circuitry (0:54), learn how optogenetics tools track the activity of neuronal populations in animals (12:38), and learn about ovarian cancer cells that are addicted to the ERBB3 oncogene.
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February 2010: Archeogenetics, a versatile transcription elongation factor, and an oncoprotein involved in leukemia
25/02/2010 Duration: 24minLearn about the earliest journeys of our ancestors revealed by archaeogenetics (0:50), a versatile transcription elongation factor with several key functions in the cell (11:12) and an oncoprotein and its many partners, which are involved in leukemia (16:21).
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January 2010: Youthful yeast cells, mosquitoes' mating songs, and slim fruit flies
28/01/2010 Duration: 20minLearn about daughter yeast cells that retain the fountain of youth (0:48), how a singing contest helps mosquitoes find the ideal mate (8:22), and a nuclear receptor that keeps fruit flies slim (13:51).