Informações:
Synopsis
Cell (www.cell.com) is a peer-reviewed journal publishing the most interesting discoveries in biology.
Episodes
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December 2009: Interviews with this year's Nobel Laureates, Dr. Elizabeth Blackburn and Dr. Venki Ramakrishnan
10/12/2009 Duration: 35minDr. Emilie Marcus talks with two of this year's Nobel Laureates, Dr. Elizabeth Blackburn and Dr. Venki Ramakrishnan about their groundbreaking research on telomeres (1:04) and the ribosome (14:29), respectively. Learn about the connection between two major molecular players in Alzheimer's disease (29:15).
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November 2009: Membrane trafficking in cells and regulation in breast cancer cells
19/11/2009 Duration: 21minLearn about two new studies identifying a protein complex that helps with intracellular membrane trafficking (start 0:47) and hear how a key cell-cycle regulator that is overexpressed in breast cancer cells is itself regulated (9:35).
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October 2009: How the influenza virus outwits the host immune system, why our ancestors took up farming, and what fruit fly memories are really made of
22/10/2009 Duration: 21minLearn about a clever way that the influenza virus outwits the host immune system (start 0:47), hear why our ancestors abandoned hunting and fishing and took up farming instead (8:55), and discover what fruit fly memories are really made of (start 13:05).
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September 2009: The mysteries of sleep, the regulation of clock genes and circadian rhythms, and breast cancer risks
24/09/2009 Duration: 21minUnravel the enduring mysteries of why we sleep (start 0:52), learn about the regulation of clock genes and circadian rhythms (9:45), and hear about a study that identifies rare variants associated with breast cancer risk (start 15:42).
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August 2009: An X-chromosome variant that protects against AIDS progression, a microRNA linking normal and cancer stem cells, and how cells move in the worm embryo
27/08/2009 Duration: 24minLearn about an X chromosome variant that protects against the progression of AIDS (start 0:50), hear about a microRNA that is decreased in both normal and cancer stem cells (start 8:08), and learn about migrating cells in the worm embryo (start 17:08).
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July 2009: How cancer cells evade detection, genes that keep the genome stable, and new therapeutic targets fortreating tuberculosis
30/07/2009 Duration: 22minLearn how cancer cells evade detection by macrophages (start 0:46), hear about a screen for genes that keep the genome stable (start 10:37) and new therapeutic targets for treating tuberculosis (start 16:12).
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June 2009: Repairing damaged lung tissue, halting liver tumor growth, and RNA as a drug target
18/06/2009 Duration: 26minLearn how stem cells can repair damaged lung tissue (start 1:04), how delivery of a microRNA to liver tumors in mice halts tumor growth (start 10:25), and why RNA could be a useful drug target (start 18:41).
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May 2009: Regulatory T cells, developing insulin resistance associated with obesity, and bladder epithelium regeneration after infection with e. coli
21/05/2009 Duration: 20minLearn how bladder epithelium regenerates after infection (0:53) and which amino acids are involved in developing insulin resistance (9:50). Hear the latest news about regulatory T cells (14:37).
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April 2009: Using stem cell therapy to treat heart disease, a key player in the production of Th17 cells, and a microRNA's role in regulating fly development
23/04/2009 Duration: 23minLearn about a microRNA that confers robustness on the pathways regulating fly development (start 0:50), the cytokine interleukin-1 which acts as a key player in the production of Th17 cells (start 10:23) and using stem cell therapy to treat heart disease (start 15:22).
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March 2009: An unexpected pro-apoptotic role for the retinoblastoma tumor suppressor, a cytoplasmic filter in neurons, and a mechanism involved in the oxidative stress response in yeast
26/03/2009 Duration: 23minLearn about an unexpected pro-apoptotic role for the retinoblastoma tumor suppressor (start 1:22), a cytoplasmic filter in neurons (start 9:35) and an intricate molecular interaction that underpins the oxidative stress response in yeast (start 17:13).
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February 2009: Melanoma cells eluding signals from a key growth control pathway, how to reprogram cells back to a pluripotent state, and variations in human genes contributing to evolution
26/02/2009 Duration: 21minHear about a new study that reveals how human melanoma cells elude signals from a key growth control pathway, how to reprogram cells back to a pluripotent state, and how variations in human genes possibly contribute to human evolution.
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January 2009: Counteracting climate change with glossy crop leaves, leaky nuclei in aging cells, and how the body keeps cholesterol in check
29/01/2009 Duration: 20minHear about a new study that reveals how aging cells end up with leaky nuclei and how the glossy leaves of crop plants may help to counteract global warming. And stay tuned to hear about a study in Cell Metabolism that explains how the body keeps cholesterol synthesis in check.
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December 2008: Looking at gene expressions in the brain, the misclassification of the Hawaiian honeyeater, and mutations involved in Diamond-Blackfan anemia
11/12/2008 Duration: 41minHear about "TRAP," a new technique for looking at gene expression in the brain and the curious classification of the Hawaiian honeyeater. You'll also learn about a large-scale screen for mutations involved in Diamond-Blackfan anemia.
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September 2008: A hormone to keep you thin, using dendritic cells to make better vaccines, and how your brain responds to fearful memories
18/09/2008 Duration: 42minHear about a lipid hormone made by fat that can keep you thin, and learn from the immunologist who discovered dendritic cells how these enigmatic cells can help to make better vaccines, and stay tuned to discover how the human brain controls responses to fearful memories and the implications for treating post-traumatic stress disorder.
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June 2008: Stem cell therapy for shiverer mice, a hormone that conserves energy during starvation, and the inner workings of a calcium ion sensor
26/06/2008 Duration: 39minHear about a study that brings us a step closer to treating neurological diseases with stem cell therapy and a metabolic hormone that conserves energy during starvation. Learn more about the inner workings of a calcium ion sensor. Finally, stay tuned for our quarterly roundup of exciting research highlights published in the Cell Press family of journals.
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April 2008: Reprogramming immune B cells, deadly brain tumors, and the insidious pathogen that causes tuberculosis
17/04/2008 Duration: 33minHear about reprogramming the body's immune B cells and also what makes brain tumors so deadly. Discover more about the insidious pathogen that causes tuberculosis ...and don't forget our quarterly round-up of exciting research highlights published in the Cell Press family of journals.
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December 2007: An immune molecule that works in the nervous system and a gene important for pigmentation in fish and humans
20/12/2007 Duration: 40minDr Ben Barres talks about about a molecule in the immune system that is important for eliminating synapses in the nervous system and we hear about a cluster of exciting research including a gene that is important for pigmentation differences in stickleback fish and humans and a protein that controls master regulators of gene expression called microRNAs
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September 2007: A potential new class of bactericidal antibiotics and long distance interactions between chromsomes
06/09/2007 Duration: 32minIncludes interviews with Dr Jim Collins about how several common antibiotics kill bacteria by generating lethal hydroxyl radicals and with Dr Rudi Grosschedl on how gene regulation can be coordinated by interactions between chromosomes.
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June 2007: Switched-off kinases, technologies to transform the research enterprise, and coaxing a human pathogen
14/06/2007 Duration: 32minIncludes interviews with Dr Jonathan Weissman about new technologies that are changing the research enterprise, Dr John Kuriyan about how kinases keep themselves switched off until they are needed, and Dr Wolf-Dieter Schubert about coaxing a human pathogen to invade a mouse.
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March 2007: Making mouse knockouts en masse, the science of sun tanning, and silencing jumping genes
09/03/2007 Duration: 30minIncludes interviews with Dr Francis Collins on the international mouse knockout program, Dr David Fisher on the role of p53 in tanning, and Dr Greg Hannon on pi RNAs silence transposons in the fly genome.