Dementia Researcher

In this podcast Dr Anna Volkmer, convenes a panel of world-renowned experts from University College London. They discuss the discovery of amyloid and its role in Alzheimer’s Disease and take an in-depth look into the latest developments surrounding Lecanemab and Donanemab, monoclonal antibodies (mAbs) as a treatment and Gene Silencing. This week’s guests are Professor Sir John Hardy, Geneticist and trailblazer in neurodegenerative disease research, Professor Nick Fox, Neurologist, and eminent figure in the fields of neuroimaging and clinical neuroscience, and Dr Cath Mummery, Neurologist and leading light in cognitive disorders and clinical trials. -- Listeners can expect: 1.

Last week Adam Smith attended the 33rd Alzheimer Europe Conference in Helsinki, Finland. In this podcast Adam and his guests bring you highlights from event, sharing news and their best bits from the hundreds of posters and talks delivered. -- This week’s guests are: Dr Victoria Shepherd, Senior Research Fello and Nurse from Cardiff University. Victoria has a special interest in research involving under-served populations with a particular focus on people with cognitive impairment. She leads a programme of methodological research exploring the ethical, legal and practical issues around research involving adults who lack capacity consent. Dr Monica Leverton, Postdoctoral Researcher at King’s College London. Monica is based within the NIHR policy institute in health and social care workforce. Her areas of interest include care for people living with dementia and the social care workforce who support them. She currently leads a project developing the role of dementia champions in homecare. Dr Danielle Jones,

Science is all about rigorous testing, empirical evidence, and painstaking documentation, right? But even in the most state-of-the-art labs, you'll find researchers who hold on to quirky rituals, lucky charms, or, dare we say it, superstitions. In this podcast, Dr Yvonne Couch, Associate Professor at University of Oxford hosts a discussion that romps through the lighter side of scientific research by exploring the wonderful world of lab superstitions. From lucky pipettes to forbidden phrases, we're about to uncover the unofficial 'do's and don'ts' that researchers swear by, or at least, swear make for good anecdotes. -- This shows guests are: Dr Kamar Ameen-Ali, Lecturer in Biomedical Science at Teeside University. In addition to teaching, Kam is interested in How neuroinflammation following traumatic brain injury contributes to the progression of neurodegenerative diseases (such as Alzheimer’s disease) that lead to dementia. Dr Soraya Meftah, Postdoctoral Research Fellow in the UK Dementia Research Insti

It's #InternationalPodcastDay so we released this show a little early to celebrate

Dr Sam Moxon is back for another show in his ‘Food for Thought’ series. In these shows Sam invites leading experts to talk about their work and the connections between diet, brain health, cognition, Alzheimer’s disease, and dementia. In this show he welcomes Dr. Helena Popovic to explore the much-debated ketogenic diet and its potential benefits for cognitive function. Helena is a best-selling author and leading authority on neuroplasticity and improving brain function. She is also a popular media commentator and regularly appears on TV and radio and was a Sydney TEDx Fast Ideas finalist. Helena graduated from the University of Sydney, Australia and her mission is to educate rather than to medicate. -- The ketogenic diet, traditionally known for its effectiveness in weight management and treating epilepsy, is making waves in the realm of neuroscience. Dr Popovic sheds light on her research, exploring how this high-fat, low-carbohydrate diet may offer new avenues for cognitive enhancement and brain health.

In this show we’re not focusing on the scientists or their discoveries, but instead we talk to some of the unsung heroes, the pillars of support behind the scenes who play an integral role in the lives of dementia researchers? We focus on the husbands, partners, and significant others of dementia researchers – who generously share their insights. Getting a glimpse into the lives of those who stand shoulder to shoulder with researchers, offering unwavering encouragement, love, and understanding. For our special family and careers week, we discuss how they support the researchers in their lives, and have a fun quiz to see just how well they know them. -- Adam Smith, Programme Director for Dementia Researcher hosts this discussion with: Andrew Lashley, self-employed Architect, father of three, and husband to Tammaryn Lashley, Professor of Neuroscience at University College London. Michael O’Reilly, Scenic Artist at the Royal Opera House, father of one, and husband to Dr Zanna Voysey, Neurologist and PhD Stud

In this special episode of the Dementia Researcher Podcast, delivered as part of our managing family life and research week, we bring you a reunion that promises insightful reflections and inspiring progress. Join host Professor Heather Mortiboys as they sit down with four exceptional researchers who graced our show five years ago. Back then, they shared their perspectives on the intricate dance between a demanding research career and the joys and challenges of family life. Now, five years later, we've invited them back to revisit those conversations and explore how their journeys have evolved. Listen in as they openly discuss the strategies they've employed, the hurdles they've overcome, and the changes they've embraced. Gain fresh insights into how they've managed to thrive in both their academic pursuits and family responsibilities. -- This week’s guests are: Dr Gemma Lace, is Associate Dean Academic (Student Experience) & Lead of the Molecular Biology Dementia Group at the University of Salford. Dr J

In this podcast Dr Anna Volkmer engages in a captivating discussion with a panel of researchers and experts from the University of East Anglia and Age UK. The focus? Hydration – a seemingly simple yet profoundly impactful aspect of well-being, especially for older individuals and those living with dementia. -- Sharing their research, learning and efforts to deliver practical changes are: Ellice Parkinson, PhD Student. With a background in clinical psychology and working in Huntington’s disease but having now worked in dementia research for almost 10 years, and now focussed on Hydration care of older people, and people living with dementia (and quickly approaching the final year of her PhD at UEA). Dan Skipper, CEO of Age UK Norwich. Dan is an active part of a range of forums focusing on improving the quality of later life in the city and county, including Norwich Older People’s Forum, Norfolk Older People’s Strategic Partnership, and the Norwich Institute of Healthy Ageing. Amy Zile, PhD Student whose work

Dr Sam Moxon has been working on a new grant and exploring how to create a spin out innovation biotech company. This work led him to meet Matthias Alder, who we just had to get on the podcast. In this show we hear from Gain Therapeutics CEO Matthias Alder. He is leading a biotech company engaged in the development of a potentially disease-modifying therapy for the treatment of neurodegenerative diseases. Hoping to unlock new treatments for difficult to treat disorders with their SEE-Tx™ supercomputer-driven, drug discovery platform targeting allosteric binding sites. There is a lot of work underway to explore modifying enzymes that have misfolded, losing their functional structure. Misfolding can lead to various diseases, including neurodegenerative disorders like Alzheimer's and Parkinson's. Researchers in this field seek, and Gain Therapeutics study the mechanisms behind enzyme misfolding, explore the consequences of misfolding on cellular functions, and develop strategies to correct or reshape these misfo

In this podcast we share a few selected highlights from the fourth day of the Alzheimer’s Association International Conference (AAIC) taking place in Amsterdam and Online, 16th – 20th July. Adam Smith hosts the show with special guests Vyshnavy Balendra from Saint James School of Medicine, Chicago. Dr Helena Popovi, Family physician, educator and author of three books from the Gold Coast in Australia and Dr Iain Hartnell, Research Communications Officer from Alzheimer’s Society. The AAIC brings together distinguished basic scientists, clinical researchers, early career investigators, clinicians and the care research community at the largest and most influential international conference on dementia science. They share theories and breakthroughs while exploring opportunities to accelerate work and elevate careers. For more information visit: https://aaic.alz.org -- You can also enjoy this show as a video podcast on our YouTube Channel. -- Find more information on our guests, and a full transcript of this

In this podcast we share a few selected highlights from the third day of the Alzheimer’s Association International Conference (AAIC) taking place in Amsterdam and Online, 16th – 20th July. Adam Smith hosts the show with special guests Dr Jayashree Dasgupta from GBHI Trinity College Dublin, Samita Kirve from Oxford Brookes University and Sarah Gregory from The University of Edinburgh. -- The AAIC brings together distinguished basic scientists, clinical researchers, early career investigators, clinicians and the care research community at the largest and most influential international conference on dementia science. They share theories and breakthroughs while exploring opportunities to accelerate work and elevate careers. For more information visit: https://aaic.alz.org -- You can also enjoy this show as a video podcast on our YouTube Channel. -- Find more information on our guests, and a full transcript of this podcast on our website at https://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and

In this podcast we share a few selected highlights from the second day of the Alzheimer’s Association International Conference (AAIC) taking place in Amsterdam and Online, 16th – 20th July. Adam Smith hosts the show with special guests Sára Erzsebet Zsadányi from Universitat Autònoma de Barcelona, Dr Sonata Mačiulskytė from Klaipeda University and Dr Aoife Cosgrave from Alzheimer’s Research UK. -- The AAIC brings together distinguished basic scientists, clinical researchers, early career investigators, clinicians and the care research community at the largest and most influential international conference on dementia science. They share theories and breakthroughs while exploring opportunities to accelerate work and elevate careers. For more information visit: https://aaic.alz.org -- You can also enjoy this show as a video podcast on our YouTube Channel. -- Find more information on our guests, and a full transcript of this podcast on our website at https://www.dementiaresearcher.nihr.ac.uk/podcast -- Th

In this podcast we share a few selected highlights from the first day of the Alzheimer’s Association International Conference (AAIC) taking place in Amsterdam and Online, 16th – 20th July. Adam Smith hosts the show with special guests Dr Mizuki Morisaki from University of Bristol, Sam Keat, PhD Student in the UK Dementia Research Institute at Cardiff University and Dr Arunima Sikdar a Postdoc Research Associate from University of North Carolina. -- The AAIC brings together distinguished basic scientists, clinical researchers, early career investigators, clinicians and the care research community at the largest and most influential international conference on dementia science. They share theories and breakthroughs while exploring opportunities to accelerate work and elevate careers. For more information visit: https://aaic.alz.org -- You can also enjoy this show as a video podcast on our YouTube Channel. -- Find more information on our guests, and a full transcript of this podcast on our website at: www.

The Dementia Researcher, ISTAART Relay Podcast is back for a fourth series. Five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. -- Part Five – Dr Shana D Stites interviews Dr Imre Lengyel representing The Eye as a Biomarker for AD PIA. -- Shana Stites is an Assistant Professor at University of Pennsylvania. As a clinical psychologist and researcher with the Penn Project on Precision Medicine for the Brain (P3MB), Shana’s research focuses on advancing diagnosis and treatment of Alzheimer’s. The goal is to understand ways to promote quality of life and psychological wellbeing. This includes understanding the impacts of the disease on individuals who may be directly affected by pathology as well as their family members. As part of this work, Shana has a special focus on better understanding how aspects of identity, such as age, gender, and race, operate as determinants in the disease experience. Shana is

The Dementia Researcher, ISTAART Relay Podcast is back for a fourth series. Five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. -- Part Four – Dr Dave Cash interviews Dr Shana D Stites representing the Diversity & Disparities PIA. -- Dave Cash is a Principal Research Fellow at University College London. Dave is a biomedical engineer that has worked predominantly in imaging (never let him near your wet lab if you like your glassware). His PhD involved image guided liver surgery at Vanderbilt University, and in 2005, he picked up and moved from the southern United States to London to do a post-doc. That led him to an opportunity to get involved in Alzheimer's disease trials. Dave is representing the ISTAART Neuroimaging PIA. -- Shana Stites is an Assistant Professor at University of Pennsylvania. As a clinical psychologist and researcher with the Penn Project on Precision Medicine for the Brain (P3MB),

The Dementia Researcher, ISTAART Relay Podcast is back for a fourth series. Five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. -- Part Three – Beth Eyre interviews Dr Dave Cash representing the Neuroimaging PIA. -- Beth Eyre is a PhD Student (although she recently submitted her thesis and will be defending very soon) at The University of Sheffield. Beth is investigating cognitive and neurovascular function in pre-clinical models of Alzheimer’s disease and in a mixed model of Alzheimer’s and atherosclerosis. Beth is representing the ISTAART Vascular Cognitive Disorders PIA. -- Dave Cash is a Principal Research Fellow at University College London. Dave is a biomedical engineer that has worked predominantly in imaging (never let him near your wet lab if you like your glassware). His PhD involved image guided liver surgery at Vanderbilt University, and in 2005, he picked up and moved from the southern U

The Dementia Researcher, ISTAART Relay Podcast is back for a fourth series. Five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. -- Part Two – Dr Maura Malpetti interviews Beth Eyre, representing the Vascular Cognitive Disorders PIA. -- Maura Malpetti is a Race Against Dementia Fellow at University of Cambridge. Maura focusses on multimodal imaging techniques (multi-tracer PET and MRI) integrated with fluid markers, post-mortem validation, and prognostic modelling approaches in frontotemporal lobar degeneration. Maura is representing the ISTAART Frontotemporal Dementia PIA. -- Beth Eyre is a PhD Student (although she recently submitted her thesis and will be defending very soon) at The University of Sheffield. Beth is investigating cognitive and neurovascular function in pre-clinical models of Alzheimer’s disease and in a mixed model of Alzheimer’s and atherosclerosis. Beth is representing the ISTAART

The Dementia Researcher, ISTAART Relay Podcast is back for a fourth series. Five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. -- Part One – Dr Imre Lengyel interviews Dr Maura Malpetti, representing the Frontotemporal Dementia PIA. -- Imre Lengyel is a Reader (Associate professor) at Queen's University Belfast. Imre is researching how we could use the eye as a less expensive, better tolerated, and faster marker to monitor the progression of neurodegeneration. He undertakes clinical eye imaging and use postmortem tissues to generate molecular and high-resolution anatomical confirmation for the changes we see in eye images. Imre is representing the ISTAART The Eye as a Biomarker for AD PIA. -- Maura Malpetti is a Race Against Dementia Fellow at University of Cambridge. Maura focusses on multimodal imaging techniques (multi-tracer PET and MRI) integrated with fluid markers, post-mortem validation, and

Adam Smith chats with Dr Claire Sexton, Senior Director, Scientific Programs and Outreach from the Alzheimer’s Association. Discussing this year’s Alzheimer’s Association International Conference (AAIC) 16 – 20 July. -- Taking place in-person in Amsterdam and online - the world’s leading basic scientists, clinical researchers, early career investigators, clinicians and the care research community will share breaking research discoveries that will lead to methods of prevention and treatment and improvements in diagnosis for Alzheimer’s disease. In this exciting edition, we will be giving you an exclusive sneak peek into one of the most highly anticipated events in dementia research conference calendar. Join us as we delve into how you can attend, the scientific programme, extra events and just what the AAIC will deliver this year. With leading experts, visionary thinkers, and research pioneers gathering under one roof, this conference promises to not only showcase groundbreaking discoveries, but also be a p

Dementia Researcher hosted a YouTube / Twitter Livestream on the 23rd June 2023 exploring Motor Neurone Disease (MND) and the remarkable advancements in research, in partnership with MND Scotland. We enjoyed the session so much, that we decided to release it as a bonus 'extra' podcast - so please ignore any references to links on the screen. Listen to learn more about the disease, the latest advancements in MND research, and specifically about the groundbreaking MND Smart Trial. This unique trial has garnered attention for its innovative approach and has shown promising potential in accelerating the discovery of effective treatments for MND. Furthermore, the event will delve into the impact of new investments in MND research, exploring how these resources are driving progress and propelling the quest for a cure. Resources mentioned during the recording: MND-SMART Website - https://mnd-smart.org/ MND Scotland Website - https://mndscotland.org.uk/ Jane Blog - https://www.dementiaresearcher.nihr.ac.uk/guest-