Science In Action

Over the past few weeks, wildfires have scorched over 1,800 square miles of land across North West America and are still going strong. Dr Mike Flannigan, professor at the Department of Renewable Resources at the University of Alberta, talks to Roland about the weather patterns and record-breaking heat causing the devastating flames. On the other side of the world, in Zambia, Dr Edgar Simulundu has been finding out why some humans attract mosquitoes more than others, and how we can use this to tackle the malaria epidemic. Also this week, Professor Novel Chegou, lead investigator at Stellenbosch University Immunology Research Group, has been awarded the 2022 Africa Prize for his innovative method for quickly diagnosing tuberculosis. And we visit the Royal Society for a very different reason. Roland checks in on the “Ukraine's Recovery: Rebuilding with Research” conference, and the discussion to use evidence based approaches for rebuilding after war. Contributors:Dr Mike Flannigan, Department of Renewable Resou

In 2003, an incredible scientific milestone was achieved as the first human genome completed sequencing. For 20 years, this genome has been used as a reference by researchers for comparison to all other DNA sequences. Now, the Human Pangenome Reference Consortium is addressing the lack of genetic diversity starting with 47 new reference genomes. Members of the consortium, Dr Karen Miga, assistant professor, UC Santa Cruz Genomics Institute and Dr Benedict Paten, associate professor, UC Santa Cruz Genomics Institute, join Roland to discuss the first stages of the project. For the first time the public will have access to thousands of documents from the Royal Society’s historical collections following their digitisation. Science correspondent Vic Gill visits the vaults to see some of these pieces of history first hand. We are also taking a trip 30km above the Earth, to the stratosphere, where Daniel Bowman, principal scientist from Sandia National Laboratories, is using solar powered balloons to listen to

India is at the centre of much of the discussion on this week’s episode of Science In Action. We hear about how a proposal to scrap Darwinian evolution from Indian secondary schools has led to signatures from thousands of scientists. Dr Vineeta Bal, Researcher at the National University of Immunology, is one of the signatories on a petition against the proposed changes. We spoke to her about why she is against them.Also in India, a new Sars-Cov-2 variant, named XBBX.16 is being studied by epidemiologists in the country. Dr Rajesh Karyakarte, professor of microbiology at BJ Government Medical College, Pune, India, is behind the study. Further study of the variant has been looked into by Kei Sato, professor of Systems Virology at the University of Tokyo. Kei has been mapping how new variants could cause us problems, ahead of them doing so. This kind of forward planning is something praised by Paul Bienaisz, Professor of Virology at The Rockefeller university. We talk to him about how vital this kind of work st

Khartoum’s National Public Health Laboratory has been caught up in the ongoing conflict in Sudan. Dr Maysoon Dahab and Dr Ayman Ahmed explain the situation and why health labs are often targeted in conflicts.Virus hunters have used artificial intelligence to discover more than 180,000 new viruses. Professor Eddie Holmes and Dr Mang Shi tell Roland how AI is completely transforming the field of viral discovery.Experts have forecasted a return to El Niño conditions later this year, which could bring with it extreme weather events. Dr Emily Becker explains how the predictions are made and the global impact of a strong El Niño.And from future to historical weather – Roland talks to Professor Ed Hawkins about the powerful Storm Ulysses of 1903, and how it can help us better understand storms today.Presenter: Roland Pease Producer: Roland Pease Assistant Producer: Sophie Ormiston

The pandemic showed Africa at the back of the global queue when it came to vaccines. That should never happen again if plans being debated in Cape Town this week go ahead. Roland talks to Seanette Wilson of South Africa's Biovac.Also in the programme: life finds a way on plastic floating in the ocean; Greenland rock dust as a global fertiliser; and designing proteins from scratch.Image Credit: Robert Bonet/NurPhoto via Getty ImagesPresenter: Roland Pease Producer: Roland Pease Assistant Producer: Sophie Ormiston

H5N1, a highly pathogenic avian flu is racing across the world, and has infected multiple species, including wild and farmed birds, and mammals from cats to sea lions. What can be done to control it? Roland Pease talks to global experts about the dangers to animal and human health, and about the measures to bring the outbreak under control.Producer: Roland Pease Assistant producer: Sophie Ormiston(Photo: A government worker examines chicks for signs of bird flu infection at a poultry farm in Darul Imarah in Indonesia's Aceh province. Credit: Chaideer Mahyuddin)

Chasing tornados in the American mid-West – scientists are trying to learn the maximum from the tornado outbreaks currently in America. Professor Karen Kosiba calls us from a radar truck studying the storms, and Professor John Allen explains the energy powering them. From the weather of today to the skies of 800 years ago... Dr Sébastien Guillet reveals how lunar observations by medieval monks are helping untangle the connection between historic eruptions and climate. Finally, we go back even further in time to the Bronze Age with Professor Elisa Guerra-Doce – to find out what drugs our ancestors were into. Image credit: Getty Images / Michael B. Thomas Producer: Roland Pease  Assistant Producer: Sophie Ormiston

We look at a gene editing breakthrough, a new technique to correct genetic errors in sick patients. Roland speaks to Professor David Liu to learn about the base editing technology.Also, we look into the complex causes of last year's post-pandemic spike in child hepatitis. Professor Judy Breuer and her colleagues may have found an explanation behind the unexpected outbreak.And the James Webb Space Telescope continues to seek out the secrets of our universe. Professor Beth Biller and Dr Elsa Ducrot have the details on the atmospheres of two very distant, and very different, exoplanets.Plus, how to get sober – for mice. Professor Steven Kliewer explains how certain mammals have evolved to deal with the intoxicating effects of ethanol. Producer: Roland Pease Assistant Producer: Sophie Ormiston(Image: Genetic engineering 3D rendered conceptual image. Credit: Getty Images)

DNA has revealed potential animal COVID carriers at the Wuhan market, but what does that tell us about the start of the pandemic? Roland talks to two of the experts behind the new analysis: Dr Florence Débarre and Professor Eddie Holmes.Also, we look into Europe’s grand new space ambitions. ESA director general Josef Aschbacher gives Roland the details of the space agency’s out-of-this-world plans.And Beethoven's last DNA: a hairy story of his family and genetic afflictions. Dr Tristan Begg shares how the composer’s tresses unlocked new information about his life and death.Image credit: Eddie HolmesProducer: Roland Pease Assistant producer: Sophie Ormiston

34 days after it first formed at the far end of the Indian Ocean, record-breaking Cyclone Freddy made a repeat landfall on Mozambique as well as passing over Malawi, causing extensive damage and loss of life. Climate scientists Liz Stephens and Izidine Pinto join Roland to give an update on the destruction and explain how Cyclone Freddy kept going for an exceptionally long time.At the Third International Human Genome Summit in London last week, Professor Katsuhiko Hayashi announced he had created baby mice from eggs formed by male mouse cells. Dr Nitzan Gonen explains the underlying science, whilst Professor Hank Greely discusses the ethics and future prospects.And from one rodent story to another, SARS-CoV-2 has been detected in brown rats scurrying around New York sewers. Dr Thomas DeLiberto from the US Department of Agriculture gives Roland the details.Image credit: Jack McBrams/Getty ImagesProducer: Roland Pease Assistant Producer: Sophie Ormiston

Human Genome Editing: The team meet experts at the Human Genome Editing Summit in London, seeking to cure genetic disease and ensure that it's safe and available to all. Roland Pease hears from Victoria Gray, the first person to be cured of the debilitating and life-shortening disease sickle cell anaemia by gene editing, and from the scientists making it possible. Also, the prospect of work to attempt gene rescue in fetuses before they are born. But the technology is expensive and complex – the question troubling the participants is to ensure people across the world can benefit from it, not just the rich and privileged. And what are the limitations of gene editing? Can it be made more effective, safer? And what of gene edits that will be inherited by future generations?

The long rains of East Africa are forecast to fail again, for the third year running, precipitating a food crisis affecting millions. Science In Action explores the science of the drought, hears about new methods improving forecasts, and what is unusual about the region that makes it so vulnerable.When we think of helium, for many of us balloons and squeaky voices come to mind. But the noble gas is critical for many aspects of modern life – and we’re facing a global shortage. Dr Annie Cheng and her colleagues at the University of Oxford are attempting to solve this by creating a model that has the potential to locate previously untapped reservoirs.Image by Gerald Anderson/Anadolu Agency via Getty ImagesProducer: Roland Pease Assistant Producer: Sophie Ormiston

Cyclone Freddy has made landfall on Madagascar, leaving destruction in its wake. At the time this edition of Science In Action is going to air, Freddy is on course to reach Mozambique and South Africa. Freddy, which has been gaining strength since it originally formed on the 30th of January, is the most powerful southern hemisphere cyclone on record. Professor Francois Engelbrecht provides the science behind the storm system.In the centre of our galaxy, an enormous cloud is heading towards the Milky Way’s supermassive black hole. Dr Anna Ciurlo tells us that this is a unique opportunity to study the influence of the black hole on the cloud’s shape and properties.We’ve heard a lot about balloons floating above Earth recently… but what about sending balloons to Venus? That’s exactly what Dr Siddharth Krishnamoorthy is proposing in order to study Venus’s seismic activity. Recorders on a “floatilla” above the planet’s surface could listen into Venus-quakes and reveal Venus’s mysterious past. And closer to home, s

In the decade since the genome editing capabilities of CRISPR-Cas9 emerged, research into novel medicines has boomed – but alongside progress comes new ethical considerations. Controversy erupted in 2018, when Chinese scientist He Jiankui created the first babies with edited genomes. After leaving prison last year, he’s now back in the lab trying to raise support for new research but refuses to discuss the ethical implications of his work. Dr Joy Zhang recently arranged a bioethics seminar and invited He Jiankui, it was the first time he’d agreed to engage with a global cohort of CRISPR scientists since returning to his research.Going back in time from cutting-edge to ancient technology, some of the oldest stone tools ever used by human ancestors have been unearthed at a fossil site in Kenya. Professor Tom Plummer talks us through the findings and how important the tools were in our evolution.And we immerse ourselves in the mysterious sounds of the Arctic and Antarctic, from singing ice to the man-made noises

In the early hours of Monday, a powerful earthquake hit Kahramanmaras in Turkey. Nine hours later another struck. When this edition of Science in Action first aired, 19,000 people were reported to have died, but that number was expected to rise. Back in 2016, Professor Asli Garagon and her colleagues accurately predicted that an earthquake of this size was coming. Using GPS, they were monitoring the East Anatolian fault to calculate energy building between the plates. With such accurate insight could Turkey have been better prepared?Ross Stein, seismologist and founder of Temblor, a Californian consultancy that specialises in assessing hazard risk, estimates the plates moved at 5,000 mph. The movement of the plates may have built up pressure in other parts of the country. And finally, Tiziana Rossetto, a civil engineer at University College London, knows better than most that earthquakes do not kill, buildings do. She tells Roland how the combination of earthquakes and subsequent aftershocks appear to have ev

Pull on an extra layer and stay toasty whilst Science in Action braces for a deep freeze. Whilst we know plenty about the ice on the Earth’s poles, Roland is on a chilling journey to see what can be found in deep space. Professor Christoph Salzmann and Professor Andrea Sella at University College London have produced a new phase of ice. Roland heads to the laboratory to see how the usual crystalline ice, found in ice cubes and icebergs, can be broken down and arranged into a new structure. The James Webb Space Telescope has detected the coldest ices to date, deep within a molecular cloud in outer space. Professor Melissa McClure describes how these clouds harbour a variety of different molecules potentially capable of forming the basic building blocks for life. From the edges of the universe to something a little closer to home, Professor Geoff Collins and colleagues have discovered odd tectonic plate activity on icy Europa, one of Jupiter’s moons. And a theory for the origin of life that may su

An outbreak of pathogenic bird flu, H5N1, in a Spanish mink farm could be a cause for concern. Some experts fear the virus may now spill over to other mammals without strict surveillance. Marion Koopmans, professor of virology at Erasmus Medical Centre, talks Roland through the potential risks. India’s caste system affects all aspects of society, but how does the hierarchy influence representation of marginalised groups in academia? Science journalist Ankur Paliwal believes that, despite efforts to combat discrimination, not enough is being done, and he has the data to prove it. Imagine a robot... Is it hard, metallic and humanoid? Professor Carmel Majidi from Carnegie Mellon University and his colleagues are thinking outside the robotics box. Their new material, magnetic in nature, can shift between solid and liquid states. It’s even capable of breaking out of robotic jail... And how do echidnas – spiny, long-nosed, egg-laying mammals – manage to stay cool during the hot Australian summers? Ima

Climate researcher, Rose Abramoff took to the stage at the American Geophysical Union (AGU) fall meetings, not as a guest speaker but in protest. Whilst her demonstration only lasted 15 seconds, she found her employment terminated from Oak Ridge National Laboratory and research stripped from the AGU programme. She was attempting to persuade other climate scientists to ‘get out of the lab and into the street’. Whilst Rose’s protest hit the headlines in the media, potentially less attention was paid to the session that was taking place at the conference, hosted by Mika Tosca, climate scientist-turn-artist, Associate Professor of Liberal Arts at the School of the Art Institute of Chicago. Roland brings the two together to discuss the event and how climate scientists should approach activism. Although there is no one solution to the climate crisis, Roland loves a brainstorm on Science in Action. Climate activist Stuart Capstick, a Cardiff University psychologist specialising in public attitudes to environmental i

Flood warnings in parts of California have seen some of the state’s best known celebrities flee their homes. The current weather conditions are in part the result of ‘Atmospheric rivers’ – literally fast flowing rivers of water vapor in the atmosphere. Marty Ralph from the Scripps Institute has been studying this phenomenon for years, he explains what atmospheric rivers are, and tells us how a greater understanding of the phenomenon is now informing weather forecasting and evacuation plans.Over the past year several million people have fled Ukraine, amongst them many scientists. Nataliya Shulga from the Ukraine Science Club is working on a wide ranging initiative to attract them back. She tells us of plans not just to reconstruct Ukrainian science facilities after the war, but to offer a philosophical change which breaks with the Soviet past - a more global, collaborative environment for scientists returning to the Ukraine. Last December the Afghan Taliban banned women from attending university, its just o

We’re taking a look back at the January 2022 eruption of Hunga Tonga-Hunga Ha’apai, which literally sent shockwaves around the world. One year on, and we’re still uncovering what made the volcano so powerful, as well as unpacking its long lasting impacts.Roland is joined by Professor Shane Cronin from the University of Auckland and Dr Marta Ribó from the Auckland University of Technology to share their findings from their latest trip to survey the volcano.The impacts of the eruption weren’t just felt on Earth – they also reached all the way to space. Physicist Claire Gasque from the University of California, Berkeley, has been analysing how the eruption affected space weather.Amongst all the material ejected by Hunga Tonga was a huge amount of water. The massive water vapour cloud is still present in our atmosphere, as Professor Simon Carn from the Michigan Technological University tells us.The volcano also triggered tsunamis worldwide. Disaster sociologist Dr Sara McBride from the US Geological Survey has be