Finding Mastery: Conversations With Michael Gervais

This week’s conversation is with Dr. David Sinclair, a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study longevity, aging and how to slow its effects.More specifically, their focus is on studying sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as metabolism, neurodegeneration, cancer, cellular reprogramming, and more.David is the co-creator and co-chief editor of the journal Aging, has co-founded several biotechnology companies, and is an inventor on 35 patents.Among the honors and awards he’s received are his inclusion in Time Magazine’s list of the “100 Most Influential People in the World” and Time's “Top 50 in Healthcare”.In addition, David is the author of the new book, Lifespan: The Revolutionary Science of Why We Age — and Why We Don’t Have To.I wanted to speak with David because he’s pushing the boundaries of what we understa