Discovery

Alana Saarinen is a 13-year-old girl who lives with her mum and dad in Michigan, USA. She loves playing golf and the piano, listening to music and hanging out with friends. In those respects, she's like many teenagers around the world. Except she's not, because Alana is one of a handful of people in the world who have DNA from three people. The BBC's Science Correspondent Rebecca Morelle explores how more children like Alana could be born. The UK is looking to legalise a new technique which would mean more children with DNA from three people could be born. This irreversibly changes the human genetic code, and would also eliminate debilitating genetic diseases. This programme examines the safety and health implications of this new science. For some it is controversial. For those who have these specific genetic diseases, it is the way to have their own healthy child. The UK is playing a pioneering role in developing the technique, called mitochondrial replacement, and Parliament are expected to vote on legalisi

Infectious bacteria are becoming resistant to the drugs that used to kill them. The last new class of antibiotics was discovered in the 1980s. There is little in the development pipelines of the world’s pharmaceutical industry. Drug companies got out of antibiotics as their attention switched to much more lucrative daily medicines for chronic diseases. Public funding on antibiotic research has also withered. Now that the gathering crisis of antibiotic resistance is becoming recognised by politicians, what are the options? Roland Pease explores how business, academia and governments might work together to avert a return to the medical dark ages.Image Credit: Hospital scientist inspects an unidentified culture in the Microbiology Department of Sydney's Royal North Shore Hospital, Greg Wood/AFP/Getty Images

The discovery and harnessing of antibiotic drugs in the mid-20th Century led some medics to predict the end of infectious diseases. But the bacteria fought and continue to fight back, evolving resistance to many of the drugs that used to kill them. Public health officials warn that without new drugs, medicine will return to the days where ‘a cut finger on Monday leads to death of Friday’. Without protective antibiotics to keep infections at bay, scores of standard surgical operations and chemotherapy for cancer will become too risky.Roland Pease looks at scientific issues behind the gathering crisis. The last new class of antibiotics was discovered in the 1980s. Are there any others in the pipeline?Image Credit: Hospital scientist inspects an unidentified culture in the Microbiology Department of Sydney's Royal North Shore Hospital, Greg Wood/AFP/Getty Images

In March astronomers in the BICEP2 collaboration announced they had found gravitational waves from the Big Bang. But now the evidence is being questioned by other scientists. Dr Lucie Green reports on the debate and asks if scientists can ever know what happened billions of years ago when the universe was formed.Image copyright: Steffen Richter, Harvard University

On 6th August, the space probe Rosetta ends its 10 year journey and arrives at Comet 67P/Churyumov-Gerasimenko. If all goes well, Rosetta will be the first spacecraft to go into orbit around a comet. The European Space Agency probe will then accompany the comet until December 2015, studying the 4 kilometre-wide lump of ice and rock dust at a level of detail far surpassing any previous comet flyby.In the words of Rosetta scientist Joel Parker, “Previous comet missions have been one-night stands, Rosetta will be there for a long term relationship.” Rosetta will stay with 67P as it heads towards and around the other side of the Sun. Rosetta will be watching everything at close quarters as the comet heats up and produces the classic gas and dust comet tail.In the final weeks of approach, the Rosetta team have realised this is going to be an even more interesting mission than they had supposed. In the middle of July, the probe’s camera revealed the bizzare shape of the comet’s nucleus. It appears to be forme

Professor Sir Michael Rutter has been described as the most illustrious and influential psychiatric scientist of his generation. His international reputation has been achieved despite the fact that as a young doctor, he had no intention of becoming a researcher, nor interest in becoming a child psychiatrist. In fact he became a world leader as both. His career has spanned more than five decades and is marked by a remarkable body of high-impact research and landmark studies. The theme running through all his work has been child development, on the subtle interplay between nature and nurture and on the factors that make the difference between a child flourishing, or floundering. Evacuated during World War Two, to a Quaker family in the USA, Mike Rutter tells Jim al-Khalili about the impact this move, aged seven, had on him. He describes the inspirational teachers who persuaded him that research and clinical work as a child and adolescent psychiatrist, was for him, and he admits that an early mentor insisted he

At the start of 2014 meteorologists warned of a possible El Nino event this year. The portents were persuasive – a warming of the central Pacific much like that which preceded the powerful El Nino event of 1997. But since then the Pacific climate system seems to have stalled. What’s going on? What are the prospects for an El Nino to develop later this year? What impacts might it have? Roland Pease delves below the Pacific surface to find out what drives El Nino cycles, the most powerful single climate fluctuation on the planet, and asks the experts why it is so hard to forecast. “The year started with a bang,” one expert tells Discovery - will it end with a whimper?(Photo: Burned swamp forest in Kalimantan. Credit: Florian Siegert, RSS GmbH)

Adam Hart looks at how new developments in understanding insect behaviour, plant cell growth and sub cellular organisation are influencing research into developing robot swarms. Biological systems have evolved elegant ways for large numbers of autonomous agents to govern themselves. Staggering colonies built by ants and termites emerge from a decentralized, self-governing system: swarm intelligence. Now, taking inspiration from termites, marine animals and even plants, European researchers are developing autonomous robot swarms, setting them increasingly difficult challenges, such as navigating a maze, searching for an object or surveying an area. At the same time, an American team has announced that its group of robots can autonomously build towers, castles and even a pyramid. Adam Hart reports on the latest developments in controlling groups of robots, and asks why models taken from the behaviour of social insects such as bees, ants and termites may be far more complex than previously thought. He also delve

General anaesthetics which act to cause reversible loss of consciousness have been used clinically for over 150 years. Yet scientists are only now really understanding how these drugs act on the brain and the body to stop us feeling pain. Linda Geddes reports on the latest research using molecular techniques and brain scanners. Linda visits the Anaesthesia Heritage Centre where William Harrop-Griffiths, president of the Association of Anaesthetists of Great Britain and Ireland, tells her about the discovery of agents that knock us out. And, as an operation takes place in the Royal United Hospital in Bath, professor Tim Cook explains the role of the anaesthetist. Linda also talks to professor Nick Franks of Imperial College, London, about his research into how anaesthetics work at the level of the cell. Irene Tracey, professor of Anaesthetic Science at Oxford University, discusses how her fMRI scans of people as they slowly undergo anaesthesia have revealed how the brain switches off. Professor Steven Laureys,

Janet Hemingway, the youngest woman to ever to become a full professor in the UK, talks about her career at the frontline of the war on malaria. Whilst many researchers look for vaccines and treatments to this global killer, Janet's approach, as a trained entomologist, has been to fight the mosquito - the vector - which transmits the malaria parasite.Image: Janet Hemingway, BBC Copyright

Geoff Watts investigates the latest thinking about our brain power in old age. He meets researchers who argue that society has overly negative views of the mental abilities of the elderly - a dismal and fatalistic outlook which is not backed up by recent discoveries and theories. Geoff talks to professor Lorraine Tyler who leads a large study in Cambridge (CamCAN) which is comparing cognition and brain structure and function in 700 people aged between 18 and 88 years old. He also meets scientists and participants involved in a unique study of cognition and ageing at the University of Edinburgh. It has traced hundreds of people who were given a nationwide intelligence test as children in 1932 and 1947. Since the year 2000, the study has been retesting their intelligence and mental agility in their 70s to 90s. The Lothian Birth Cohort study is revealing what we all might do in life to keep our minds fast and sharp well into old age. One new and controversial idea holds that cognitive decline is in fact a myth.

Jack Stewart meets the engineers who are building vehicles that drive themselves. He has a ride in Google's driverless car, which has no steering wheel and no pedals. Google's Chris Urmson explains the company's approach to autonomous vehicles. Jack visits Stanford University's driverless car project where professor Chris Gerdes shows him Shelley, an automated Audi that races around a track at speed as well as a human driver. Chris is collaborating with a philosopher to explore some of the difficult questions around autonomous vehicles, such as who is liable if there's an accident. Is it the human or the car? And ,Jack meets Josh Swirtes whose company, Peloton, is linking trucks together with the idea that they should have fewer accidents. (Photo: Jack Stewart in Stanford's University X1)

Most traffic accidents are caused by human error. Engineers are designing vehicles with built in sensors that send messages to other cars, trucks, bikes and even pedestrians, to prevent collisions happening. The idea is to make the vehicles react to whatever's going on faster than the human drivers. Jack Stewart drives around the university town of Ann Arbor, in Michigan, in some of the many vehicles that are fitted with experimental devices in the world's largest connected vehicles project. He finds out how the system works from researchers at UMTRI, the University of Michigan's Transportation Research Institute, including the director, professor Peter Sweatman and human factors expert Dr Jim Sayer, Kirk Steudle, Director, Michigan Department of Transportation and a resident who has had her car fitted with an experimental device. (Photo: Right hand wing mirror, Nevada, USA, BBC copyright)

ITER is the most complex experiment ever attempted on this planet. Its aim, to demonstrate that nuclear fusion, the power of the Sun, can give us pollution free energy that we can use for millions of years. But at the moment, it's still largely a vast building site in the Haut Provence of southern France, with little prospect of any nuclear reactions there for another decade. A recent management report made damning criticisms of the way ITER is run, of the relations between the central organisations, and the seven partners (USA, Russia, Japan, China, South Korea, India and Europe) contributing to the project. Roland Pease has been to Cadarache to see how work is progressing, and to hear of the hopes of the scientists who have dedicated their working lives to the dream. (Photo: The empty magnet-winding hall at ITER, BBC copyright)

Dr Tiffany Jenkins asks what our brains can tell us about art. Can there ever be a recipe for beauty? Or are the great works beyond the powers of neuroscience? She talks to Professor Semir Zeki of University College London, the first person to coin the term, neuroaesthetics, about what happens in the brain when people in a scanner see paintings or hear music. Professor Gabi Starr at New York University tells Tiffany Jenkins why she thinks there are parts of the brain that light up when we like an art work. Tiffany visits Christie's auction house to explore whether the best art always commands the best prices.She also talks to Martin Kemp, Emeritus Professor of Art History at Oxford University, about our different responses to authentic paintings and to fakes. And Tiffany discusses with art critic JJ Charlesworth why neuroscience is having an influence in some areas of art appreciation.Picture: The reflection of trees in water, Credit: Getty

Alf Adams FRS, physicist at the University of Surrey, had an idea on a beach in the mid-eighties that made the modern internet, CD and DVD players, and even bar-code readers possible. You probably have half a dozen 'strained-layer quantum well lasers' in your home.Image credit: Alf Adams, BBC Copyright

Mark Miodownik's chronic interest in materials began in rather unhappy circumstances. He was stabbed in the back, with a razor, on his way to school. When he saw the tiny piece of steel that had caused him so much harm, he became obsessed with how it could it be so sharp and so strong. And he's been materials-mad ever since. Working at a nuclear weapons laboratory in the US, he enjoyed huge budgets and the freedom to make the most amazing materials. But he gave that up to work with artists and designers because he believes that if you ignore the sensual aspects of materials, you end up with materials that people don't want. For Mark, making is as important as reading and writing. It's an expression of who we are, like music or literature, and 'everyone should be doing it'. To this end, he wants our public libraries to be converted into public workshops, with laser cutters and 3 D printers in place of books.Image: Mark Miodownik, BBC Copyright

Forensic anthropologist professor Sue Black began her career with a Saturday job working in a butcher's shop. At the time she didn't realise that this would be the start of a lifelong fascination with anatomy. Her job has taken her to some extreme and challenging locations to identify human bodies, such as Kosovo, where she uncovered evidence used in the UN's War Crimes Tribunal in The Hague. Back home, Sue has been integral in solving many high-profile criminal cases, including cracking Scotland's biggest paedophile ring in 2009. In The Life Scientific, Jim al-Khalili asks how she deals with the emotional pressures of the job, and why she is so fascinated by the inner workings of the human body. In her spare time, Sue Black also advises crime fiction authors like Val McDermid, providing inspiration for new plotlines and characters. In return, Val and a group of writers have offered to help with Sue's latest challenge - fundraising for a mortuary. This facility will use new techniques to embalm bodies and pro

Whatever happened to biofuels? They were seen as the replacement for fossil fuels until it was realised they were being grown on land that should have been used for food crops. But now there is serious research into new ways of producing biofuels, from waste materials, from algae and from bacteria. Gaia Vince takes to the water of Strangford Lough in Northern Ireland where Professor Matthew Dring and Dr Karen Mooney from Queens University, Belfast, are experimenting in growing algae that could be turned into fuel. She visits Professor Alison Smith's algae lab at Cambridge University. Graham Ellis from Solazyme in California explains how his company has already made fuel from algae that has been sold at the pumps and powered a plane, in a mixture with conventional fuel. And Professor Nick Turner at Manchester University and Professor John Love at Exeter University talk about how they are manipulating bacteria to make diesel.

Biofuels were hailed as the environmental solution to fossil fuels not that long ago. Made from living crops they take up carbon dioxide as they grow. So burning them shouldn’t disturb the balance of warming gases in the atmosphere. But for the last few years the publicity about biofuels has been mainly negative. And for good reason – biofuels are made from crops such as oil palm - grown in place of food crops or even rainforests. In some cases using these crops actually produces more CO2 than burning fossil fuels. However research is being done into new kinds of biofuels that aren’t in competition with food crops. Gaia Vince travels to Bavaria in Germany to meet Dr Markus Rarbach, head of biofuels at Clariant. This company has set up a demonstration plant that produces ethanol from sugars in the waste products of wheat grown nearby. Also on the programme is professor Gregory Tucker from Nottingham University who talks about research into new ways of getting sugars out of the inedible parts of crops; agricult