Discovery

Addictions researcher, Dr Sally Marlow, investigates fears that easy access to powerful painkillers could be creating a large, but hidden problem of addiction. Painkillers are widely available over the counter, and combinations containing codeine, which is addictive, can be purchased from pharmacists and on the internet.Teenager, Alice, tells Sally about secretly buying huge numbers of painkillers on her way to school while she was wearing her school uniform. She used her lunch money to buy multiple packs from several stores, switching shops when she was questioned by pharmacists. And Steve describes how his serious codeine addiction began after treating tooth pain with the drug. The side effects helped his anxiety and for years he was doctoring tablets in order to increase his codeine intake. Some health professionals believe easy access is fuelling a potential health crisis and say those with serious dependency problems, are hidden below the healthcare radar. Only a tiny percentage of people with an addicti

European Inventor of the Year, Chris Toumazou, reveals how his personal life and early research lie at the heart of his inventions. As chief scientist at the Institute of Biomedical Engineering at Imperial College London, Chris inspires engineers, doctors and other scientists to create medical devices for the 21st Century. Applying silicon chip technology, more commonly found inside mobile phones, he tackles seemingly insurmountable problems in medicine to create devices that bridge the electronic and biological worlds - from a digital plaster that monitors a patient's vital signs to an artificial pancreas to treat diabetes. His latest creation, coined a 'lab on a chip', analyses a person's DNA within minutes outside the laboratory. The hand-held device can identify genetic differences which dictate a person's susceptibility to hereditary diseases and how they will react to a drug like warfarin, used to treat blood clots. (Photo: Chris Toumazou, BBC copyright)

It is the nearest and most dominant object in our night sky, and has inspired artists, astronauts and astronomers. But fundamental questions remain about our only natural satellite. Where does the Moon come from? Although humans first walked on the Moon over four decades ago, we still know surprisingly little about the lunar body's origin. Samples returned by the Apollo missions have somewhat confounded scientists' ideas about how the Moon was formed. Its presence is thought to be due to another planet colliding with the early Earth, causing an extraordinary giant impact, and in the process, forming the Moon. But, analysing chemicals in Apollo's rock samples has revealed that the Moon could be much more similar to Earth itself than any potential impactor. Geochemist Professor Alex Halliday of the University of Oxford, and Dr Jeff Andrews-Hanna, Colorado School of Mines – who is analysing the results from Nasa's Gravity Recovery and Interior Laboratory (GRAIL) lunar mission – discuss the theories and evidence

They call them 'The Unexpected Survivors'. The casualties from the war in Afghanistan whose injuries were so severe that they were not expected to survive, but who survived nevertheless. In October, after 13 years Britain and the United States officially brought their combat operations in Helmand Afghanistan to an end. Camp Bastion, the coalition stronghold – once one of the largest military bases in the world – has been dismantled leaving a handful of buildings that will now be handed over to the Afghan National Army.First established eight years ago in 2006, Camp Bastion came to host to one of the most extraordinary and successful trauma medical systems ever seen. Amongst the medics that went to and served in Afghanistan were doctors who trained with me in civilian hospitals. With the mission nearly at an end I had to see them and their system for myself, to try and understand just how it came to be and why it worked so well.Photo courtesy of Ministry of Defence

Dr Kevin Fong explores the development of modern trauma medicine and discovers how the lessons from conflict and catastrophe have equipped us to deal with even the worst disasters, providing a system that could save lives that would otherwise have been lost. First of two programmes.

Professor Brian Cox of Manchester University describes how he gave up appearing on Top of the Pops to study quarks, quasars and quantum mechanics. Although he describes himself as a simple-minded Northern bloke, he has acquired an almost God-like status on our TV screens, while the ‘Cox effect’ is thought to explain the significant boost to university admissions to read physics. He talks to Jim al-Khalili about learning to be famous, his passion for physics and how he sometimes has difficulty crossing the road. In 2005 Brian was awarded a Royal Society Research Fellowship for his work on high energy particle collisions at CERN and elsewhere – an enviable academic achievement. In 2009, he was voted one of the sexiest men alive by People magazine. He has invented a new kind of celebrity – a scientist who is regularly snapped by the paparazzi.Brian wants everyone to be as excited as he is about the laws that govern our universe - the beautiful, counter-intuitive and often weird world of quantum mechanics that ex

You have a headache and take a pill. The headache is gone, but what about the pill? What we flush away makes its way through sewers, treatment works, rivers and streams and finally back to your tap. Along the way most of the drugs we take are removed but the tiny amounts that remain are having effects. Feminised fish in our rivers, starlings feeding on Prozac-rich worms, and bacteria developing antibiotic resistance - scientists are just beginning to understand how the drugs we take are leaving their mark on the environment. The compounds we excrete are also telling tales on us. Professor of Chemistry, Andrea Sella, gets up close and personal with music festival toilets to find out what the revellers are swallowing, and hears from scientists who are sampling our rivers to learn about our health. Producer: Lorna Stewart(Photo: Laboratory technician, testing a urine sample for traces of any banned substances or stimulants. BBC copyright)

Patient power is on the rise. But is it rising too far? Frustrated by the time it takes to develop new drugs, the ethical barriers to obtaining clinical data or the indifference of the medical profession to obscure diseases, patients are setting up their own clinical trials and overturning the norms of clinical research. A DIY clinical trial sounds like a joke – and a dangerous one at that. But as Vivienne Parry discovers, it's real and on the rise as greater access to medical data allows more patients to play research scientists and medics at their own game. Patients lie at the very heart of clinical research – without them there is none. Yet they come way down the food chain when it comes to transparency about their own health, blinded as they usually are to what pills they are taking and whether they are actually doing them any good. Even after the trial is published they are left with little understanding of whether the treatment could work for them and licensing is usually years away. So it is perhaps ha

Diseases devastate livestock around the world. In chickens for example the deadly strain of bird flu and the lesser known bacterial infection Campylobacter, not only harms the chickens but is also a real threat to human health. Melissa Hogenboom visits one of the world’s leading genetics institutions, the Roslin Institute in Edinburgh in the UK and hears about new genetic techniques to combat diseases in our livestock. In chickens, professor Helen Sang uses a subtle form of genetic modification, called genome editing. Her team is trying to find the genetic components of natural resistance in a wide group of chicken breeds, which they can then insert into the genome of livestock fowl in the hope of breeding healthier, safer chickens. They are close to making disease resistant birds but they are aware that GM animals are still a long way from entering the market in Europe. Similar research is going on in cows for TB resistance, but here instead of genetically modifying they are cross-breeding which may take ten

Rebecca Morelle talks to explorers of deep ocean trenches, from film-maker James Cameron to biologists discovering dark realms of weird pink gelatinous fish and gigantic crustaceans. The deepest regions of the ocean lie between 6,000 and 11,000 metres. Oceanographers term this the Hadal Zone. It exists where the floor of abyss plunges into long trough-like features, known as ocean trenches. The Hadal zone is the final frontier of exploration and ecological science on the planet. At its most extreme, the water pressure rises to 1 tonne per square centimetre and the temperature drops to 1 degree C. Despite the challenging conditions, some animals survive and thrive in the trenches. Because the technical challenges to operating there are so high, we are only now just learning what is down there and how creatures adapt to life in the extremes. Based at the University of Aberdeen in Scotland, deep sea ecologist Alan Jamieson is one of the premier explorers of life in the Hadal zone. In the programme, he talks thro

Gaia Vince looks at the future of power transmission. As power generation becomes increasingly mixed and demand increases, what does the grid of the future look like?

Accidents happen in science labs all over the world, but when you’re working with deadly pathogens the consequences can be disastrous. The reputation of America’s ‘gold standard’ The Centres for Disease Control and Prevention in Georgia has recently become tarnished as news emerged that 80 workers were inadvertently exposed to live anthrax, and a deadly strain of flu was accidentally sent to another lab. Further reports of tick-box safety culture, lethal samples sent in ziplock plastic bags and vials of smallpox from the 1950s being found in the back of a fridge have increased calls for a review of the work being done on some of the world’s most dangerous pathogens.Andrew Luck-Baker looks at the impact of these recent biosafety lapses for BBC WS Discovery. Some scientists are now arguing for the reduction of laboratories working with deadly viruses and the closing down of research which is potentially risky. But does the benefit of the work outweigh its potential risks to the public? And how can human error b

Alana Saarinen is a 13-year-old girl who lives with her mum and dad in Michigan, USA. She loves playing golf and the piano, listening to music and hanging out with friends. In those respects, she's like many teenagers around the world. Except she's not, because Alana is one of a handful of people in the world who have DNA from three people. The BBC's Science Correspondent Rebecca Morelle explores how more children like Alana could be born. The UK is looking to legalise a new technique which would mean more children with DNA from three people could be born. This irreversibly changes the human genetic code, and would also eliminate debilitating genetic diseases. This programme examines the safety and health implications of this new science. For some it is controversial. For those who have these specific genetic diseases, it is the way to have their own healthy child. The UK is playing a pioneering role in developing the technique, called mitochondrial replacement, and Parliament are expected to vote on legalisi

Infectious bacteria are becoming resistant to the drugs that used to kill them. The last new class of antibiotics was discovered in the 1980s. There is little in the development pipelines of the world’s pharmaceutical industry. Drug companies got out of antibiotics as their attention switched to much more lucrative daily medicines for chronic diseases. Public funding on antibiotic research has also withered. Now that the gathering crisis of antibiotic resistance is becoming recognised by politicians, what are the options? Roland Pease explores how business, academia and governments might work together to avert a return to the medical dark ages.Image Credit: Hospital scientist inspects an unidentified culture in the Microbiology Department of Sydney's Royal North Shore Hospital, Greg Wood/AFP/Getty Images

The discovery and harnessing of antibiotic drugs in the mid-20th Century led some medics to predict the end of infectious diseases. But the bacteria fought and continue to fight back, evolving resistance to many of the drugs that used to kill them. Public health officials warn that without new drugs, medicine will return to the days where ‘a cut finger on Monday leads to death of Friday’. Without protective antibiotics to keep infections at bay, scores of standard surgical operations and chemotherapy for cancer will become too risky.Roland Pease looks at scientific issues behind the gathering crisis. The last new class of antibiotics was discovered in the 1980s. Are there any others in the pipeline?Image Credit: Hospital scientist inspects an unidentified culture in the Microbiology Department of Sydney's Royal North Shore Hospital, Greg Wood/AFP/Getty Images

In March astronomers in the BICEP2 collaboration announced they had found gravitational waves from the Big Bang. But now the evidence is being questioned by other scientists. Dr Lucie Green reports on the debate and asks if scientists can ever know what happened billions of years ago when the universe was formed.Image copyright: Steffen Richter, Harvard University

On 6th August, the space probe Rosetta ends its 10 year journey and arrives at Comet 67P/Churyumov-Gerasimenko. If all goes well, Rosetta will be the first spacecraft to go into orbit around a comet. The European Space Agency probe will then accompany the comet until December 2015, studying the 4 kilometre-wide lump of ice and rock dust at a level of detail far surpassing any previous comet flyby.In the words of Rosetta scientist Joel Parker, “Previous comet missions have been one-night stands, Rosetta will be there for a long term relationship.” Rosetta will stay with 67P as it heads towards and around the other side of the Sun. Rosetta will be watching everything at close quarters as the comet heats up and produces the classic gas and dust comet tail.In the final weeks of approach, the Rosetta team have realised this is going to be an even more interesting mission than they had supposed. In the middle of July, the probe’s camera revealed the bizzare shape of the comet’s nucleus. It appears to be forme

Professor Sir Michael Rutter has been described as the most illustrious and influential psychiatric scientist of his generation. His international reputation has been achieved despite the fact that as a young doctor, he had no intention of becoming a researcher, nor interest in becoming a child psychiatrist. In fact he became a world leader as both. His career has spanned more than five decades and is marked by a remarkable body of high-impact research and landmark studies. The theme running through all his work has been child development, on the subtle interplay between nature and nurture and on the factors that make the difference between a child flourishing, or floundering. Evacuated during World War Two, to a Quaker family in the USA, Mike Rutter tells Jim al-Khalili about the impact this move, aged seven, had on him. He describes the inspirational teachers who persuaded him that research and clinical work as a child and adolescent psychiatrist, was for him, and he admits that an early mentor insisted he

At the start of 2014 meteorologists warned of a possible El Nino event this year. The portents were persuasive – a warming of the central Pacific much like that which preceded the powerful El Nino event of 1997. But since then the Pacific climate system seems to have stalled. What’s going on? What are the prospects for an El Nino to develop later this year? What impacts might it have? Roland Pease delves below the Pacific surface to find out what drives El Nino cycles, the most powerful single climate fluctuation on the planet, and asks the experts why it is so hard to forecast. “The year started with a bang,” one expert tells Discovery - will it end with a whimper?(Photo: Burned swamp forest in Kalimantan. Credit: Florian Siegert, RSS GmbH)

Adam Hart looks at how new developments in understanding insect behaviour, plant cell growth and sub cellular organisation are influencing research into developing robot swarms. Biological systems have evolved elegant ways for large numbers of autonomous agents to govern themselves. Staggering colonies built by ants and termites emerge from a decentralized, self-governing system: swarm intelligence. Now, taking inspiration from termites, marine animals and even plants, European researchers are developing autonomous robot swarms, setting them increasingly difficult challenges, such as navigating a maze, searching for an object or surveying an area. At the same time, an American team has announced that its group of robots can autonomously build towers, castles and even a pyramid. Adam Hart reports on the latest developments in controlling groups of robots, and asks why models taken from the behaviour of social insects such as bees, ants and termites may be far more complex than previously thought. He also delve