Discovery

Kevin Fong talks to Venki Ramakrishnan, Professor of structural biology in Cambridge and joint-winner of the Nobel Prize in Chemistry in 2009. Celebrated for his work on the ribosome, the remarkable molecular machine at the heart of all cell biology, Ramakrishnan was knighted for services to Science in 2012 and later this year, will become the first Indian-born president of the Royal Society, the oldest and most prestigious scientific body in the world. And yet, as Kevin discovers, his education and early academic career was anything but predictable or conventional and included being rejected from both Indian and US Universities multiple times.Image: presenter Kevin Fong with Venki Ramakrishnan, BBC Copyright

Kathryn Maitland is a doctor with a burning passion to transform clinical research across Africa, where she has spent most of her career. Determined to improve the outcomes for critically sick children in hospital, she spent over a decade of her life raising funds for and then carrying out, the first ever scientific trial for fluid bolus resuscitation in children with shock. Fluid replacement is a pillar of medicine but the evidence base for this particular issue is weak, even though it is standard practice for hospitals in high-income countries. The results were totally unexpected, creating a shockwave in the medical community that is yet to settle down. Kathryn believes the results could save tens of thousands of lives every year in Africa alone yet the experience very nearly ended her research career. She tells her life-changing story to Kevin Fong, himself a critical care doctor, who wonders if his own current practice of treating sick children should now change.(Image: presenter Kevin Fong with Kath

Earlier in the year, the reported remarks about 'the problem with girls' by British biologist and Nobel Laureate Professor Tim Hunt' brought the issues facing women scientists into public spotlight. Although there have been questions about the reports of what exactly happened and what was said during Hunt's talk in South Korea, the story has given female researchers the rare opportunity to air the problems of gender bias in science to a much wider audience.What are the factors holding back women in science? What can be done to improve gender equality in the lab? Claudia Hammond talks to women scientists in India, Nigeria, Bolivia, the US and the UK about their experiences and views. The programme features: ecologist Monica Moraes at the Universidad Mayor de San Andres in Bolivia; neuroscientist Jennifer Raymond in Stanford, California; psychologist Uta Frith at UCL in London; chemist Paul Walton of the University of York; and physicists Rabia Salihu Sa'id at Bayero University in northern Nigeria and Shobh

Dr Mark Porter is a family doctor in the UK and in his 50s. He’s tall and slim and thinks he’s fit and healthy – after all he goes to the gym several times a week. Mark meets experts who measure his weight, height and body fat to find out if he is as healthy as he seems. He begins by finding out his BMI, or body mass index, a term more and more people are using all over the world. It’s an indicator of whether he is too fat, too thin or just right. It’s relatively easy to work out with a calculator – he divides his weight in kilograms by the square of his height in metres. Mark compares his BMI against two other ways of measuring body fat, the true test of whether he is overweight or not. Is his BMI as accurate as the results of body fat calculations derived by measuring skin folds and an ultra accurate DEXA scan? (Photo: Overweight man measuring his waist. Credit: Science Photo Library)

Today, astronomers believe the universe is a violent, constantly changing place. But it was not always the case. At the beginning of the 19th century, many believed fervently that the celestial sky was a constant, divinely perfected, completed creation. But as telescopes got larger, the mystery of the number, origin and role of the "nebulae" - those colourful, cloud-like smudges on the sky – grew and grew. Were they really vast clouds of gas and dust as they sometimes appeared? Or were they merely closely packed, very distant clusters of stars, as some of them allegedly appeared when magnified through the great reflecting telescopes? When some astronomers and writers suggested they were in fact a vision of creation in action, matter condensing to form stars and planets like our own, some establishment religious figures cried foul, fearing the social implications. Could bigger telescopes resolve the crisis? For most of the 19th century, the biggest telescope in the world was in Birr, Ireland, then known as Par

In 1856, a teenager experimenting at home accidentally made a colour that was more gaudy and garish than anything that had gone before. William Perkin was messing about at home, trying to make the anti-malarial Quinine - but his experiment went wrong. Instead he made a purple dye that took Victorian London by storm. Philip Ball tells the story of this famous stroke of serendipity. Laurence Llewelyn- Bowen describes the fashion sensation that ensued and chemist, Andrea Sella tells how Perkin's purple prompted the creation of much more than colourful crinolines. (Photo: William Henry Perkin (1838-1907), British chemist. Credit: Science Photo Library)

What does it take to be remembered well? The discovery of the structure of DNA is often attributed to James Watson and Francis Crick. But a third man shared the stage with them for the 1962 Nobel Prize for medicine - Maurice Wilkins. He was a brilliant physicist who after work on the Manhattan Project was determined to move from "the science of death to the science of life". He made his mark in the fast progressing world of x-ray crystallography and in the late 1940s was the first to propose that biological material that passed on genetic information from one generation to the next might have an order and structure that scientists could elucidate and control. He was to play an integral role one of the most important discoveries of the 20th Century. But why did he fail to capture the public imagination? Kevin Fong examines Maurice Wilkins achievements offering a new slant on the familiar story of the race to unravel DNA.(Photo: Professor Maurice Wilkins. Credit: Keystone/Hulton Archve)

Naomi Alderman tells the story of James Watt and the steam engine that nearly never got made. A breath of steam hits cold metal. It cools suddenly and becomes a drop of water. There an idea. But the designs for Watt’s radically more efficient steam engine laid on the shelf in his workshop for years. Watt, a depressive, cautious perfectionist had no interest in actually making engines. Had it not been for his friend, the businessmen Matthew Boulton driving him on, his engine might never have left the drawing board. Naomi talks to historian, Jenny Uglow about the five friends who kick started the industrial revolution. And, digital guru Bill Thompson talks about the scientific legacy of Watt’s obsession with getting a patent - an obsession which led to an Act of Parliament. Photo: James Watt. Credit: Hulton Archive)

A sonic tour of the universe, with solar scientist, Dr Lucie Green. In the previous episode, we listened in to the sounds of the Solar System. This week in Discovery, we travel further out into the cosmos to bring you more Sounds of Space.Some are recorded sound, others are data – like X-rays or radio waves - that have been sonified. All of them have inspired scientists and artists to help us understand our universe.Joining Lucie Green on this sonic journey through space are:- Prof Tim O'Brien (Associate Director of Jodrell Bank Observatory)- Honor Harger (Executive Director of the ArtScience museum in Singapore) - Dr Andrew Pontzen (Cosmology Research Group, University College London)Producer: Michelle MartinImage: Whirlpool Galaxy Credit, NASA Hubble

The previously silent world of outer space is getting noisier. In this audio tour of the Solar System, Dr Lucie Green listens in to the Sounds of Space. You may have heard the famous ‘singing comet’ – the soundscape created using measurements taken by the Rosetta spacecraft. Now, we bring you more sounds that have come from our exploration of the cosmos.Some have been recorded by microphones on-board interplanetary spacecraft. Others have been sonified from space data, from lightning on Jupiter to vibrations inside the Sun. All of them reveal tantalising secrets that have inspired scientists, artists and musicians to help us understand the universe beyond.Joining Lucie Green on this sonic journey through space are: Prof Tim O'Brien, associate director of Jodrell Bank Observatory, Honor Harger, executive director of the ArtScience museum in Singapore, Dr Andrew Pontzen from the Cosmology Research Group, University College London.(Photo: Saturn By Voyager. Credit: Nasa)

A debate about the state of scientific research in Europe, recorded in Brussels on the day when the European Research Council was celebrating its 5000th grant. Since 2007 the ERC has written cheques totalling the equivalent of around 10 Billion dollars. Presenter Gareth Mitchell is joined by biologist Dr Iva Tolic of the Ruder Boskovic Institute in the Croatian capital Zagreb and the 5000th grantee, European research commissioner Carlos Moedas, Dr Veerle Huvenne, who is originally from Belgium but is currently based in Southampton in the south of England, where she is a marine geoscientist, and the ERC president, Jean-Pierre Bourguignon. They discuss how the ERC decides which scientists to support and whether its funds can make Europe an attractive place for scientists from all over the world to work. Iva Tolic and Veerle Huvenne explain how their grants help them do their research. Dr Tolic works on how cells divide and Dr Huvenne on marine biodiversity. And, can European science can compete with research in

Tracey Logan takes us back to the wild west of America, and looks at the extraordinary feud that came to be known as the Bone Wars. This is a tale of corruption, bribery and sabotage - not by cowboys, but by two palaeontologists, Edward Drinker Cope and Othniel Charles Marsh, who would stop at nothing in their race to find new dinosaur fossils. This was the golden age of dinosaur discovery, and their bitter war led to the discovery of some of our most iconic dinosaur species: Stegosaurus, Triceratops, Diplodocus and Camarasuarus to name a few. What led these two seemingly respectable men of science to behave in such an unseemly way, and what was the legacy of this now infamous feud? Tracey Logan investigates. (Photo: Drawing of Apatosaurus dinosaur, BBC Copyright)

As a young woman, Stephanie Shirley worked at the Dollis Hill Research Station building computers from scratch but she told young admirers that she worked for the Post Office, hoping they would think she sold stamps. In the early 60s she changed her name to Steve and started selling computer programmes to companies who had no idea what they were or what they could do, employing only mothers who worked from home writing code by hand with pen and pencil and then posted it to her. By the mid-80s her software company employed 8,000 people, still mainly women with children. She made an absolute fortune but these days Stephanie thinks less about making money and much more about how best to give it away. (Photo: Stephanie Shirley. BBC copyright)

Is our desire to wage war something uniquely human or can its origins be traced much further back in our evolutionary past? To suggest that warfare is a regular feature of human civilization would be to state the obvious. But just how deeply rooted is our desire to kill others of our species? Is lethal aggression a fixed part of our genetic code, something that has evolved from a common ancestor – and something therefore that has adaptive value? Or is warfare – and more generally, a predilection for lethal violence something that has emerged much more recently in human history? No longer the preserve of historians and philosophers, the question, as Geoff Watts discovers, is now argued over fiercely by anthropologists and biologists. Producer: Rami TzabarImage Credit: Chimpanzee, courtesy of Getty

Could birdsong tell us something about the evolution of human language? Language is arguably the single thing that most defines what it is to be human and unique as a species. But its origins and its apparent sudden emergence around a hundred thousand years ago, remains mysterious and perplexing to researchers. But could something called vocal learning provide a vital clue as to how language might have evolved? The ability to learn and imitate sounds - vocal learning - is something that humans share with only a few other species, most notably, songbirds. Charles Darwin noticed this similarity as far back as 1871 in the Descent of Man and in the last couple of decades, research has uncovered a whole host of similarities in the way humans and songbirds perceive and process speech and song. But just how useful are animal models of vocal communication in understanding how human language might have evolved? Why is it that there seem to be parallels with songbirds but little evidence that our closest primate relati

Biologists are using light to explore the brain - and to alter it. Roland Pease meets some of the leading players in optogenetics, who use light-sensitive molecules to take direct control of neural systems in worms, flies, and maybe one day, humans. For some, it's a way of exploring the interplay of electricity and chemistry as neuron talks to neuron in complex brains. For others it opens the way to future therapies for conditions like motor neuron disease, in which dying nerves bring about paralysis, and epilepsy, brought about by runaway oscillations in brain waves.(Photo: Elegans nemotodes, or round worms, undergo examination by project scientists at the Kennedy Space Center in Florida. Credit: Getty Images)

Roland Pease looks into perovskites - the materials enthusiasts say could transform solar power. Solar power is the fastest growing form of renewable energy. But most of it collected by panels made of silicon - the material that also goes into computer chips. But silicon is an old technology, and researchers have long sought a material that is both better at capturing sunlight. And cheaper to make.Perovskites, which first emerged into the lab just a few years ago, promise to be just that material. Roland Pease meets the experts who have made this happen, and finds out what makes perovskites so good - and what wrinkles still have to be ironed out.Image credit: 1999 EyeWire, Inc

Dr Susie Mitchell hears the story of the 19th Century Scottish scientist James Clerk Maxwell. Maxwell's lifelong curiosity about the world and his gift for solving complicated puzzles led him to a string of discoveries. He was the first person to demonstrate a way of taking colour photographs, and he used mathematics to work out what the rings of Saturn were made of before any telescope or spacecraft was able to observe them close up. His most important achievement however was the discovery of electromagnetism, as neatly described by four now famous lines of equations. His prediction of electromagnetic waves led on to a huge range of today’s technology, from mobile phones and wi-fi equipment to radio, X-rays and microwave ovens. Albert Einstein considered him a genius, and another scientist Heinrich Hertz described him as ‘Maestro Maxwell’. The 2015 International Year of Light celebrates, amongst other events, the anniversary of his ground-breaking publication about electromagnetism. So the only question is -

In this edition of Discovery, Erika Wright explores the science of Stammering, a widely misunderstood condition that occurs at the same level in all cultures, countries and languages. There is a window of opportunity in early childhood when stammering begins but is also a time of natural faltering when help may not be required, so therapists and parents have to decide when and whether to intervene. To add to the complexity many young children who stammer will recover naturally – although the exact number is debated and so therefore, is the incidence of stammering – but it’s universally agreed that to identify those that will persist is critical. There are clear risk factors for Stammering and Discovery speaks to the professor of speech pathology who has made it a lifelong quest to study the common factors that may place children at risk.There is news of a new trial using brain stimulation while adults who stutter talk on the beat, to see if word fluency can be enhanced.And new initiatives in Rwanda and Burki

Just twenty years ago, the British Antarctic Survey (BAS) would not allow women to camp in Antarctica. In 2013, it appointed Jane Francis as its Director. Jane tells Jim Al-Khalili how an intimate understanding of petrified wood and fossilised leaves took her from Dorset’s Jurassic coast to this icy land mass. Camping on Antarctic ice is not for everyone but Jane is addicted, even if she does crave celery and occasionally wish that she could wash her hair. Fossils buried under the ice contain vital clues about ancient climates and can be used to check current computer models of climate change. The earth can withstand a great range of temperatures: Antarctica was once covered in lush forest. But the question is: can humans adapt? As the ice caps melt, sea levels will continue to rise. And, says Jane, the time to start planning for that is now.Image: Courtesy of Jane Francis