Science In Action

The 2024 north Atlantic hurricane season has started with a bang, with Hurricane Beryl traversing the whole ocean, and leaving a trail of destruction across the Caribbean, into Mexico and Texas. Presenter Roland Pease speaks to climate expert Michael Mann of Pennsylvania University about this hurricane season and the role of climate change.And Roland speaks to Amie Eisfeld of the Influenza Research Institute at the University of Wisconsin–Madison, who has been looking at the infection and transmission of bovine H5N1 influenza (bird flu). The virus is shown to be transmitted through the milk of cows with bovine flu to mice and by intranasal exposure to mice and ferrets. The findings are published in Nature this week.Ancient genomics: Neolithic farmers hit hard by the plague. Repeated outbreaks of plague may have contributed to the decline in Neolithic populations in Scandinavia, a Nature paper suggests. The analysis of ancient DNA from more than 100 individuals sheds light on the fate of these farmers around 5

Science in Action is at the UK's Royal Society Summer Science Exhibition, hunting for dark matter, melting ancient ice, cleaning up disused mines and looking for the batteries of the future. Presenter: Roland Pease Producer: Alex Mansfield Production Coordinator: Jana Bennett-Holesworth(Image: Pile of used batteries ready for recycling. Credit: Mindful Media via Getty Images)

An injectable antiviral "PrEP" therapy that gives 100% protection against HIV infection. Trials among young women in South Africa and Uganda proved so effective, they were wound up early to accelerate its use. Linda-Gail Bekker of the Desmond Tutu HIV Foundation shares her excitement. A new kind of gene therapy that uses the cell's own “epigenetic” mechanisms to silence troublesome portions of our DNA, tested against the prion protein responsible for some brain diseases. Jonathan Weissman led the research at the Whitehead Institute for Biomedical Research in Massachusetts. Accelerated evolution is being tested in Matthew Nitschke’s labs in the Australian Institute for Marine Science to see if it can help protect natural corals against future global warming. The amazing 4.200 km transatlantic flight of some Painted Lady butterflies – and the extraordinary detective work ecologist Gerard Talavera and team needed to prove it. Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Jana Ben

How has China reached the top spot of scientific research so quickly? Science editor of The Economist, Ainslie Johnstone, gives us the CCPs grand, broad plans whilst senior reporter for Nature, Gemma Conroy, digs into the specifics of China’s future particle collider. Also, Gene Kirtsky, who has been studying cicadas for 50 years, discusses the spectacle of the millions of insects which have been emerging across the USA this summer. And Unexpected Elements' Marnie Chesterton gets close and personal with the stinkiest plant in the world at Kew Garden in London. Presenter: Roland Pease Producer: Ella Hubber Production co-ordinator: Jana Bennett-Holesworth(Photo: Jiangmen Underground Neutrino Observatory under construction. Credit: VCG/Getty Images.)

With mice being the latest species to carry the disease, pandemic expert Rick Bright calls for stronger counter measures. “It’s like PTSD from February 2020” he says. The authorities in the USA are responding too slow to the spread of H5N1 bird flu through its dairy farms – even mice are carrying the virus now, and not enough is known of how it is evolving and whether humans are threatened. He talks Roland through the complex political and public health issues. Child sacrifices in the Mayan empire a thousand years ago have been confirmed with DNA evidence from bones recovered in the 1960s from an underground pit. Some victims were twins, possibly indicating a brutal ritualistic re-enactment of an ancient myth involving divine twins. Geneticist Rodrigo Barquera describes the analysis. Mature orchids perform a unique form of offspring-care, feeding tiny seedlings with nutrients via networks of thread-like fungal hyphae in the soil, according to experiments conducted at Sheffield University. Mycologist Katie Fi

The ‘origami’ superpowers of a single-celled pond hunter, it hunts by launching a neck-like proboscis that can extend more than 30 times its body length. Manu Prakash of Stanford University reveals the amazing mathematical mechanisms of the protist, Lacrymaria olor.It’s a microbe-eat-microbe world out there, with bacteria waging constant war against each other. It’s by dipping into their ever-evolving chemical arsenal that we keep our pharmacies supplied with the antibiotics we use to fight infectious bacteria - and computer biologist Luis Coelho of Queensland University of Technology has turned to genetics and AI to speed up the search for novel compounds.Research from Elana Hobkirk at Durham University has found that the process of domestication and selective breeding has limited the ability of domestic dogs to use facial expressions to convey emotions as effectively as their wolf ancestors. Whilst we may be easily manipulated by the ‘puppy eyes’ of our pet dogs, they are no longer able to display the same

AI is already being used in every branch of science, and will become more and more a feature of future breakthroughs. But with its power to find subtle patterns in massive data sets comes a concern about how we will know when to trust its outcomes, and how to rely on its predictions. Science in Action talks to Alison Noble who just completed a Royal Society report on trust in scientific AI.With highly pathogenic bird flu infecting around 70 dairy herds across 10 states in the USA, including a herd of alpacas, we get an update from health journalist Helen Branswell of StatNews on the latest science and efforts to get on top of the infection.Also, from the pioneers of the mRNA vaccines that helped turn around the COVID pandemic, an experimental version that could be rolled out rapidly if the bird flu does cross worryingly into people. University of Pennsylvania’s Scott Hensley described how it works, and how promising it looks.Science in Action also hears how Europe’s new EarthCARE satellite, equipped to peer d

Fentanyl is a powerful morphine substitute, but it is also incredibly addictive – millions struggle with weaning themselves off it. And of the 600,000 drug deaths worldwide each year, the World Health Organisation estimates 80% are due to opioids in general, with synthetic opioids like fentanyl being a growing part of the problem. New work with genetically manipulated mice suggests that fentanyl affects two parts of the brain, one associated with the high, but also another that regulates fear. This knowledge could aid in the development of treatments to reduce addiction to the opioid. Early developers: Long before a developing implants into a mother's uterus, in fact as the fertilised egg divides for the first time into a pair of cells, which line becomes the future baby and which will become the 'life support' system of the placenta has been decided. Embryologist Magdalena Zernicka-Goetz explains why this early unfolding of the genetic programme is important, and why it's taken so long to discover it. Gett

They were the best northern and southern lights in decades, but why? And what’s next? We hear from astrophysicist Steph Yardley about the solar maximum, geomagnetic storms and atmospheric spectaculars.Also, the impossible heatwave in the Philippines made possible by global warming – the analysis of a continent-spanning climate extreme by the World Weather Attribution collaboration.Getting close up to raging tornadoes in order to fill in the big gaps that remain in the science of their development.And the tale of the lizard’s tail, and how it could lead to safer buildings in the future. (Photo: The aurora borealis, also known as the 'northern lights’, are seen over The Roaches near Leek, Staffordshire, Britain, May 10, 2024. Credit: Carl Recine/Reuters)Presenter: Roland Pease Producer: Jonathan Blackwell

Could future blood transfusions be made safer by mixing in a new bacterial enzyme? Every year 118 million blood donations need to be carefully sorted to ensure the correct blood types go to the right patients. Prof Martin Olsson, of Lund University in Sweden, and colleagues in Denmark have published a study that suggests an enzyme made by bacteria in our gut could edit our blood cells to effectively convert type A, B and AB to type O. This would be a step towards a universal blood type that could be given to any patient. Papua New Guinea’s Naomi Longa is a “Sea Woman of Melanesia”. She works to train local women from the Kimbe Bay region of the Coral Triangle to dive, snorkel, navigate and use AI to monitor the coral reefs there. She is winner of this year’s Whitley Award, and tells us why it is socially and scientifically useful to get locals - specifically females - involved in conservation efforts there. Data scientist and roboticist Prof Daniele Rus of MIT has been using Machine Learning to decipher stru

As bird flu is found in US farm cats fed on raw cow’s milk, chimpanzees are observed eating infected bat dung instead of vegetables. There is a constant threat of infections crossing from species to us and also from species to other species, particularly because of what we do. That is, after all, what happened to start the pandemic.We hear about the ongoing struggles of the Chinese virologist who broke his instructions in China in order to share the first COVID genetic data.And a strange tale of how tobacco growing might provide bat viruses a path into other species.Presenter: Roland Pease Producer: Alex Mansfield Production co-ordinator: Jana Bennett-HolesworthImage: Cows on an American cattle farm (Credit: Adam Davis/EPA-EFE/REX/Shutterstock)

Friday, April 13th 2029 – mark it in your calendar. That’s the day an asteroid the size of an aircraft carrier will fly past Earth, closer than some satellites. Don’t worry – it will miss, but it’ll will pass so close to Earth that it will be visible to the naked eye of 2 billion people, particularly in North Africa and Western Europe.Roland Pease this week attended the Apophis T-5 Years conference at the European Space Research and Technology Centre (ESTEC) in the Netherlands, meeting astronomers scrambling to get missions up to the object to learn what kind of threats such asteroids might pose to us in the future and to discuss the science of planetary defence. NASA’s OSIRIS-APEX, a follow-on to OSIRIS-REx, will study the physical changes due to the gravitational forces from the Earth as it closely passes us by. But will there be an armada of spacecraft sent to monitor Apophis? The European Space Agency hope to gather support for their own mission, RAMSES.Presenter: Roland Pease Producer: Jonathan Blackwell

A black hole just discovered in our Milky Way galaxy, weighing 33 times the mass of the Sun, and dating back to near the time of the Big Bang, gives new clues to the origins of this dark astronomical mysteries. And dancing with a Sun-like star in our galactic neighbourhood, it offers a great opportunity for astronomers to take a detailed look in coming years, as astronomer Professor Gerry Gilmore of Cambridge University tells the programme. Presenter Roland Pease has headed to the lab of Professor Ludovic Orlando in Toulouse, France where they are extracting ancient DNA from horses as part of a project called “Horsepower” - to reveal how our prehistoric ancestors tamed and domesticated these powerful animals (long after cattle and sheep) and in the process helped shape the extraordinary history of the first states of China and Mongolia. And a deep look into the mechanisms of addiction – showing how drugs of abuse, such as cocaine, hijack the neuronal pathways that had evolved to drive our innate needs

The highly pathogenic strain of bird flu, H5N1, has arrived on the continent. Australian bird specialist Megan Dewar, from the Federation University of Australia, has led a mission aboard the research ship the Australis. Science in Action remembers physicist Peter Higgs 60 years after his Nobel prize winning theory of the Higgs particle. The unfolding scandal of manipulated data behind claims of incredible room-temperature superconductivity. Science writer Dan Garisto has seen the details in a Rochester University internal investigation. And the alga – single-celled seaweed – with superpowers. As well as capturing carbon from CO2 in the atmosphere, like other plants, this one can directly capture nitrogen too, essential for life, but which few organisms can do for themselves. We hear from the marine scientist who has revealed this evolutionary trick. Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Jana Bennett-Holesworth (Image: KAPPA-FLU team selecting skua carcasses for pos

A powerful earthquake hit Taiwan on Wednesday morning, but thanks to the country’s early warning system and engineering-preparedness, there was little destruction and few deaths. Seismologist Ross Stein, CEO of earthquake consultancy Temblor, Inc., shares his analysis. The highly pathogenic bird flu H5N1 has been detected in cattle in the US and in a cattle handler in Texas. To learn more about this special animal-to-human transmission, Roland speaks to virologist Richard Webby of St. Jude Children’s Research Hospital in Tennessee and Director of the World Health Organization Collaborating Center for Studies on the Ecology of Influenza in Animals. French Space Institute Supaero in Toulouse is collaborating with Japan’s space agency JAXA to send and land a rover on Phobos, one of Mars’ tiny moons. Roland travels to the University of Toulouse to learn more about building this wheeled Rover from Supaero’s Naomi Murdoch. Transitioning to a clean energy future requires mining materials like rare earth minera

3000 light years from Earth, a white dwarf star called T Coronae Borealis is on the brink of a “once-in-a-lifetime” explosion. Astrophysicist Bradley Schaefer is enthusiastic about the bright star set to appear in the night sky in the coming months. Professor Irving Weissman has been researching ways to restore youth using mouse models for decades. He has sewn old and young mice together to join their circulatory systems and has found that giving old mice blood from younger mice reverses some signs of ageing. In his group’s paper, the use of an antibody-based therapy has been shown to restore a declining immune system in ageing mice. Not quite the fountain of youth but potentially a key step in halting many age-related diseases. Roland gets the details from Irving and first-author Dr Jason Ross. And, in the small town of Cabrières in Southern France, producer Ella Hubber goes on the hunt for some 480-million-year-old fossils with part-time fossil prospectors Eric and Sylvie Monceret. Their latest excavation

The last great "out of Arica" movement of our ancestors swept out of the northeast of the continent 74,000 years ago. Archaeologist John Kappelman of the University of Texas brings us an update to this complex tale in the form of animal carcasses. We take a trip to Oxford to meet some of postgraduate researcher Ally Morton-Hayward's archive of preserved brains. Not only is Ally shining a light on these underappreciated brains, she is also using them to unlock a rich treasure-trove of information about our ancestors and how they were preserved.How do you develop and promote a vaccine against a widespread but neglected parasite? Maria Elena Bottazzi from Baylor College of Medicine is in India promoting their latest development in creating a hookworm vaccine that works against these life-limiting childhood parasites. And, is the Chandra X-Ray Observatory at risk? In a decision that has shocked astronomers, the functioning telescope is on the chopping block because of NASA budget cuts. We hear from Belinda Wilke

After a twelve-month set of climate records driven by global warming it is time to take stock of how we’re impacting the planet as a species. Coral biologist Kate Quigley, of the Minderoo Foundation and James Cook University, dives into the 8th mass bleaching event at the Great Barrier Reef. We explore how deadly heat stress continues to threaten this underwater paradise and induce mass sickness in the corals that call it home. Heading onto land we reunite with Mike Flannigan, Professor of Fire Science at Thompson Rivers University, after a record-breaking Canadian forest fire season in 2023 we ask if conditions are set for a repeat. And what about the human cost of these climbing temperatures? In the future 800 million outdoor workers in the tropics may be exposed to intolerable heat stress. However, Yuta Masuda, director of science at the Paul G Allen Family Foundation, advises that options for individual action may be limited for workers to protect themselves. One of the driving forces behind a record

Astronomers using the James Webb Space Telescope think they have seen the glow from the first generation of stars after the Big Bang. Newton Kavli Fellow Hannah Übler discusses. The Anthropocene is meant to mean the latest geological era in which humanity is shaping the rocks and environment of our planet. But an unexpected vote by a commission has declined the idea of making this an official definition. Roland hears from one of its leading proponents, geologist Jan Zalasiewicz, about what happened and why it matters. And, new research indicates that bumblebees can show each other how to solve puzzles too complex for them to learn on their own. Professor Lars Chittka put these clever insects to the test and found that they could learn through social interaction. How exactly did the experiment work, and what does this mean for our understanding of social insects? Reporter Hannah Fisher visits the bee lab at Queen Mary University in London. Plus, the subterranean South American snake, or rather snake-like amphi

The All of Us Research Program is undergoing the herculean task of gathering genomic data from over one million people living in the United States, from widely different backgrounds, in the hopes of accelerating health care research. However, within the scientific community many, including Ewan Birney, deputy director general of the European Molecular Biology Laboratory, are concerned that the way some of this data has been framed in a recent paper could reinforce racist beliefs. We also learn about the program and hear a response to the criticism from Josh Denny, the CEO of the All of Us Research Program. Over the past two years, a deadly version of bird flu, H5N1, has been spreading around the globe, killing hundreds of thousands of birds and mammals in the process. Isolated from the rest of the world, animals in Antarctica have been safe from the virus so far. But, virologist Antonio Alcamí, who is located on the continents Spanish base, confirms that bird flu has reached them, infecting Antarctic skua se