Science In Action

Remdesivir a drug eventually rejected as a treatment for Ebola seems to have aided recovery in a trial with more than a thousand Covid -19 patients. Researchers are cautious but hopeful; a leading health official in the US has made comparisons with the impact of game changing drugs used to treat HIV. In contrast an organisation researching the mechanisms by which bat coronaviruses infect humans has had its funding cut following criticism from President Trump.A scheme to help manufacture ventilators and protective equipment worldwide has seen some success with a simple ventilator they developed, now in use in hospitals.And we look at climate change –with this year set for extreme weather(Image: Liberian photographer Alphanso Appleton took this picture of a schoolgirl and sent it to the Wellcome Trust, to express thanks for their and others’ efforts to develop an Ebola vaccine. Credit: Alphanso Appleton/Wellcome Trust)Presenter: Roland Pease Producer: Julian Siddle

President Trump has repeated unfounded claims that scientists created Covid-19 in a lab. Rigorous scrutiny of the genetics of the virus reveals no evidence for such a claim. And Brazil’s President Bolsonaro is at odds with his own health advisors – splitting public opinion and action over lockdown measures needed to control the virus. We also look at why Covid -19 seems to be associated with so many different symptoms, from diarrheal infections to complicating kidney disease, to heart attacks And some potentially good news from HIV research, a new target to stop that virus in its tracks, which might also be useful in the fight against other viruses. (Image: President Trump with Brazilian President Bolsonaro. Credit: Getty Images)Presenter: Roland Pease Producer: Julian Siddle

Italy is beginning its first tentative steps towards ending its lockdown. These are small steps, opening a few shops in areas where virus transmission has seen big falls. Part of the reason for this controlled strategy is that there are real concerns over a potential resurgence of the virus, Around the world there are now hundreds of trials on drug treatments for Covid-19. Results so far are mixed, with antivirals developed for Ebola and HIV showing positive signs, but antimalarial drugs, championed by President Trump in particular have been shown to have dangerous potentially life threatening side effects.A warning from history, more than 500 years ago suggests the western US in particular is entering an extreme drought, a ‘Megadrought’. When this last happened it led to war, depopulation and the spread of disease.And its 10 years since the Deepwater Horizon oil spill in the Gulf of Mexico. Studies of fish in the region suggest they are still affected by oil from that spill and more recent lesser known pollu

Massively over crowded Moria refugee camp on the Greek island of Lesbos has seen numbers grow from 5 to 20 thousand in a matter of months. Hundreds of people share taps and toilets, there is little chance to implement measures designed to stop the spread of covid 19. So far the camp has not been hit by the epidemic, but aid agencies fear for the most vulnerable in the camp. Covid 19 jumped from bats to humans, possibly via another wild animal. A study of zoonotic diseases has identified many other viruses that could do the same. The skies are clearer, levels of pollution from traffic have dropped by up to 50 percent but how long will cleaner air remain?And Comet Borisov makes a spectacular exit.(Image: Moria refugee camp, Lesvos, Greece. Credit: Getty Images)Presenter: Roland Pease Producer: Julian Siddle

Nigeria has seen a small number of Covid -19 cases, largely spread amongst the most affluent, people who travel abroad, However there is concern about the potential of the virus to spread to overcrowded slum areas. In such conditions social distancing measures would be difficult to enforce. What are the alternatives? The US now has the majority of cases of the virus, New York has been heavily hit, medics have developed an app to help understand the spread of Covid 19 in the community. The availability of test kits is an issue worldwide, we look at a novel idea, adapting a device made from paper that could help to see whether the virus is present in wastewater.The WHO has launched international drug trials to tackle covid 19, but none of the drugs involved were developed specifically to target this virus we look at why they might just work. (Image: Getty Images)Presenter: Roland Pease Producer: Julian Siddle

The strong social distancing policies introduced by China seem to have been successful in stopping the spread of Covid 19. Without any effective drug treatments, reducing our number of contacts is the most effective way to prevent viral transmission.We also look at the similarities been policies in Russia and the US on how best to deal with the virus. In both cases there are contradictions and disagreements between medical professionals and politicians. And a warning from Polio, how vaccines may create problems when immunisation campaigns do not reach everyone. (Image: Getty Images)Presenter: Roland Pease Producer: Julian Siddle

In Italy the entire population of a small town was tested for Covid 19. Of those infected, one in three people with no symptoms had the virus. And from China researchers found many people carried the virus – even before authorities there began tracking its spread. The findings suggest vulnerable people may contract the virus from those without symptoms.And we’ve news of a breakthrough - new tests looking at Covid 19 antibodies, These should help provide a picture of developing immunity to the virus. However as growing numbers of people fall ill there are concerns over a potential shortage of hospital ventilators globally, These are needed to treat the most severe cases. However a crowdsourcing project has been set up to try and kick start the manufacturing of a variety of different types of ventilator that could be built around the world. If you have knowledge of ventilators or their use and would like to get involved more information is available here. http://bit.ly/frontiertech4COVIDaction(Image: AFP/Getty

Covid- 19 cases seem to be multiplying daily and there is now a growing body of scientific evidence both on its spread and the effectiveness of measures to try and control it. We look at what’s working, what’s not and why. And we look to the potential for coronavirus drug treatments, why despite the hype there really isn’t anything round the corner.Australia’s recent fire season was intense; a new study looks back over 500 years of the weather pattern partly responsible, the Indian Ocean Dipole. The findings show the most extreme years occurred recently – under the influence of man-made climate change. And we look at life deep below the sea floor, microbes which multiply slowly over centuries and eat their neighbours. (Image: Coronavirus test. Credit: iStock / Getty Images Plus)Presenter: Roland Pease Producer: Julian Siddle

Attributing Australia's bush fires, a major study says man-made climate change was a big driver – making the fires at least 30% worse than they would have been if natural processes were the only factors.We look at preparations for coronavirus in Africa. Although cases there are currently lower than in much of the rest of the world a major training initiative is taking place to spread awareness amongst medics across the continent.We ask why Horseshoe bats in particular carry coronaviruses, and find a novel idea for distributing vaccines in places without refrigeration.(Image: Australian bushfires. Credit: Getty images/AFP)Presenter: Roland Pease Producer: Julian Siddle

The appearance of Covid -19 in Italy and Iran surprised many this week. As the virus continues to spread we look at ways to contain it.Australia’s fires have burnt around 20 percent of the countries woodlands, what are the implications for the recovery of those ecosystems?And what is the link between the world’s super rich and deforestation? Unsurprisingly it’s money.And we hear about the unexpected cooling effects of hydroelectric dams.(Image: Tourists wearing masks tour outside the Coliseum in Rome. Credit: Getty Images)Presenter: Roland Pease Producer Julian Siddle.

Researchers at the London School of Hygiene and Tropical medicine have developed an online map which presents the latest information on the spread of CoVid-19 and allows anyone to follow the outbreak and compare this data with the spread of Ebola and SARS. See the weblink from this page to try it for yourself.And the coming together of microbiology and big data science has led to the development of a portable device able to spot antibiotic resistant bacteria. This should help with more precise drug targeting and potentially save lives.We also look at how social science is helping to improve the health of people reliant on woodstoves for cooking, and we unearth a huge impact crater hidden in plain sight. (Image:Getty Images)

Doctors in the US have treated a coronavirus patient with a drug developed for Ebola. That drug had never been tested on people so its use here seems an extreme move. We look at why this kind of drug developed for one virus might work on another. It’s all down to the genetic material at the centre of the virus. That raises safety concerns as human cells contain similar material.East Africa is experiencing a plague of locusts and bizarrely it’s linked to the Australian wildfires. A weather pattern across the Indian Ocean, made more extreme by climate change, links the rains in Africa with the heatwave in Australia.New features of The Northern Lights have been discovered thanks to an analysis of photos on Facebook by physicists in Finland. Amateur sky watchers pictures reveal previously unnoticed forms in the light display.And we look at the search for properties of sub atomic particles, why a small device might be better than the enormous ones used so far.(Image: Scientists are at work as they try to find an e

Parts of China are on lockdown, a small number of cases have been reported in other countries and the past week has brought widely conflicting views on the potential danger presented by the new virus. We look at the scientific facts, analyse why it’s so difficult to predict the spread of the virus, look at the nature of virus infection and discuss why treatments such as vaccines are not available. We look at why some viruses can jump from animals to humans and examine hi-tech solutions designed to speed up the process of drug development.Image: Medical staff member helps a couple at a hospital in Wuhan. Credit: Feature China/Barcroft Media via Getty Images)Presenter: Roland Pease Producer: Julian Siddle

The way in which a new virus has emerged in China is reminiscent of SARS, a highly infectious virus that spread rapidly. It’s so similar that Health officials demanded action as soon as its existence became known. And the Chinese authorities and global medical community have acted to try and stop the spread. Events were still developing, even as we were in the studio making this programme, new reports of suspected cases were coming in. The WHO was yet to give its view on the severity of the outbreak. This week’s edition is very much a snapshot of what we know or knew about this virus on the afternoon of Thursday January 23rd 2020.(Image: Wuhan Residents wear masks to buy vegetables in the market. Credit: Getty Images)Presenter: Roland Pease Producer: Julian Siddle

An experimental satellite called Aeolus, named after a Greek god of wind, which takes daily global measurements of the wind patterns throughout the depth of atmosphere has improved weather forecasts. ESA’s Anne-Greta Straume explains how it works. The dramatic eruption of the island volcano Taal in the Philippines was a spectacular picture of the plume of ejecta punching a hole in overlying cloud cover. Nearby towns have been blanketed with dust, fissures have appeared in the ground and there has been dramatic lightning. Geologist Yannick Withoos at Leicester University is studying historic eruptions of Taal and current events have brought the purpose of her research into sharp relief.Philipp Heck of the Field Museum in Chicago explains how he has found the oldest dust grains on earth inside a Murchison meteorite. They are millions of years older than the solar system. And Roland Pease talks to Brian Rauch of Washington University, St ouis, who is currently in Antarctica flying detectors on balloons around t

2019 was Australia’s hottest year on record, a major factor behind the bush fires which have been far worse than usual. We look at the patterns of extreme weather that have contributed to the fires but are also linked to floods in Africa. And the way in which thunderstorms have helped to spread the fires. The armpit of Orion is changing. The star Betelgeuse is dimming some claim this is readying it for a major explosion others are more sceptical, we weight up the arguments. And an Iron Age brain may hold some clues to modern neurodegenerative disease. Protein fragments have been extracted from the brain tissue found inside a 2,500 year old human skull.(Image: Australia fires. Credit: Getty Images)Presenter: Roland Pease Producer: Julian Siddle

Roland Pease is joined by California based science Journalist Molly Bentley as we examine the impact of earthquakes and fires. California has experienced both in the last year - What’s it like to live with a constant threat from these extreme events? We also take a look at NASA’s plans for a new mission to Mars – to look for signs on life.Picture: Roland Pease with science journalist Molly Bentley, Credit: BBC

The latest round of climate negotiations, COP25, have ended without agreement on many fundamental issues. We join researchers from Perdue University in the US who have developed a role-playing game to encourage climate negotiators and others to take a long-term view. Key to this research project is the concept of tipping points, where an environment changes irreversibly from one state to another. This is accompanied by the loss of ecosystems - for example, the widespread melting of Arctic sea ice, rainforest burning or coral bleaching. The idea is that such tipping points provide a more meaning full focus for the implication of climate change than abstract concepts like temperature rise.Image: Polar bear in the Arctic Sea (Credit: Coldimages/Getty)

We have the latest from a year long investigation into the causes of the December 2018 Indonesian Tsunami. And we get a look at the first pictures from the Mayotte undersea volcano, which emerged earlier this year off the coast of East Africa. (Anak Krakatau volcano. Credit: AFP/Getty Images) Presenter: Roland Pease Producer: Julian Siddle

This week’s programme comes from the world’s largest earth sciences conference, the American Geophysical Union in San Francisco.Roland Pease talks with Diana Roman of the Carnegie Institution for Science in Washington DC about the tragic White Island volcanic eruption in which at least eight tourists died.Aurora Elmore of National Geographic and Arbindra Khadka of Tribhuvan University in Kathmandu Nepal discuss the state of Himalayan glaciers and climate change.Robert Hazen of the Carnegie Institution for Science in Washington DC tells Roland about the research area called geobiochemistry and Hilairy Hartnett of Arizona State University explains why it may not be easy to find life on extra solar planets. (Image: Smoke from the volcanic eruption of Whakaari, also known as White Island. Credit: Reuters)Presenter: Roland Pease Producer: Julian Siddle