Synopsis
Podcast by Future Science Group
Episodes
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CN Bio In Focus Podcast
05/06/2023 Duration: 12minIn this Tech Blast episode supported by CN Bio (Cambridge, UK), their Lead Scientist Emily Richardson and Principal Bioengineer Dharaminder Singh talk us through organ-on-a-chip (OOC) technologies. From what they are and how they work to what kind of data they provide and their future applications, Emily and Dharaminder provide all the information you need to understand the basics of OOC.
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Beyond the Abstract: an interview with Anthony Breton
05/06/2023 Duration: 07minIn our new podcast series, we're joined by a Bioanalysis author to review the publication's biggest challenges, wider implications and next steps. In this first episode, we're joined by early career Researcher Anthony Breton to discuss volumetric absorptive microsampling (VAMS®) as an alternative to venepuncture for the assessment of essential and toxic elements.
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Mixed reality technologies in medical and surgical applications: an interview with Taylor Kantor
31/05/2023 Duration: 27minMixed reality technologies in medical and surgical applications: an interview with Taylor Kantor
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Long-read sequencing for the metagenomic analysis of microbiomes
10/05/2023 Duration: 22minIn this episode, sponsored by Zymo Research, we explore the microbiome and how long-read sequencing techniques are changing our approach to the field and the exciting discoveries that they have led to. To do this we speak to Kris Locken, Molecular Biologist in the Research & Development department of Zymo Research (CA, USA), and Jeremy Wilkinson, Global Marketing Specialist for Microbial Genomics at PacBio (CA, USA). Find out how microbes compare to nuts and what this means for the challenges of metagenomic sample preparation, how long reads can stack up vs short reads for metagenome assembly and much more, all in this latest episode of Talking Techniques Contents:Intro: 00:00-01:55 What is metagenomics and why is it important for microbial studies? 01:55-03:55 How has long-read sequencing impacted metagenomics? 03:55-06:05 Long-read vs short-read sequencing workflows: 06:05-07:15 Addressing barriers to long-read sequencing: 07:15-08:45 Sample preparation for long-read sequencing: 08:45-12:20 Developmen
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Tech Blast | Gene expression analysis
17/04/2023 Duration: 12minIn this Tech Blast episode supported by Thermo Fisher Scientific (MA, USA), Associate Product Manager Jon Flasher talks us through gene expression analysis, some of its challenges and the tools available to streamline the process. Listen to learn more about how Thermo's TaqMan Gene Expression Assays can be used to address research questions around cancer, biomarker identification, hereditary diseases, neurological diseases and the body's response to pathogens like COVID-19. Products mentioned in this podcast are for research use only, not for use in diagnostics.
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Editor's Picks | March
31/03/2023 Duration: 05minIn this episode of Editor’s Picks, hear about how researchers have taken biotechnology to a whole new level, moving individual cells with sound waves, and geckos are more socially intelligent than we thought….
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The power of intentional mentoring: an interview with Heather Beasley
16/02/2023 Duration: 19minHello and welcome to the latest episode of OCTalks, the podcast series from Oncology Central. I am Jade Parker, Senior Editor of Oncology Central. Today I am joined by Heather Beasley who is a post-doctoral scholar at Vanderbilt University (TN, USA). Heather’s research focuses on calcium signaling in breast cancer, as well as the dysregulation of bone metabolism due to comorbidities such as hypercalcemia.
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Open neuroscience and the meaning of FAIR
03/02/2023 Duration: 37minThis episode, our second recorded at Neuroscience 2022 (13-19th April 2022; San Diego, CA, USA), delves into the importance of open data in neuroscience and the FAIR guidelines, which encourage researchers to make their data Findable, Accessible, Interoperable and Reusable. Sharing her considerable expertise in this area is one of the authors of the FAIR guidelines, Maryann Martone, who provides some key examples of the successes that open data practices have delivered so far and cautionary tales for how current practices are damaging the field. Listen on to find out how to implement open data practices, how they can help your lab and why Maryann sees it as our responsibility to resolve! Contents: Introduction: 00:00-02:00Introducing open neuroscience and the meaning of FAIR 02:00-03:00Exposing outdated paradigms in science: academic targets, publications, reproducibility and data accessibility: 03:00-06.30Incentivizing open data and reassigning value restructuring academia: 06:30-08.40The impact of FAIR w
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Tech Blast | Lab automation
30/01/2023 Duration: 11minIn this Tech Blast episode, we discuss lab automation with Gregory Lee, Automation Manager at Zymo Research (CA, USA). We explore the types of tasks that can be automated, Greg’s three Ts to consider when thinking about automation ¬– technical, throughput and turnaround time – and his top tips for implementing automation. Greg also shares common pitfalls labs fall into when attempting to deploy automation, reminding us to never forget about the box. Contents: • Introduction: 00:00–00:40 • What does automation look like in a lab setting? 00:40–01:40 • What tasks can be automated? 01:40–02:30 • Greg’s three Ts: 2:30–03:50 • The benefits of automation: 03:50–05:15 • Greg’s top tips for implementing automation: 05:15–07:00 • Common pitfalls – it’s not all about the instrument: 07:00–08:10 • Think outside the box, but don’t forget it exists: 08:10–09:05 • Is automation our future? 09:05–10:45
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Editor's Picks | January
26/01/2023 Duration: 05minOn this month’s episode of Editor’s Picks, we’re celebrating the 40th birthday of PCR, saving the northern white rhinoceros from the brink of extinction and connecting the dots between HPV, the vaginal microbiome and race.
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Welcome to the jungle: sequencing for conservation
19/01/2023 Duration: 43minIn this episode of Talking Techniques, we head to the Ecuadorian rainforest to chat about the use of sequencing in conservation with Zane Libke, a field researcher based at Sumak Kawsay In Situ (Pastaza, Ecuador). Zane discusses how he turned his fascination with nature into a career, his current work using nanopore sequencing technologies to find undescribed species and helping train future field researchers. We also explore the benefits of fighting biodiversity in a more local-centric way and using research to protect the area from exploitative companies. Contents:Intro: 00:00–01:35Zane’s work at Sumak Kawsay In Situ: 01:35–05:05Turning a fascination with nature into a career: 05:05–08:20The importance of sequencing for conservation: 08:20–12:25Technologies being used to sequence in the field: 12:25–14:15Portable nanopore sequencing with the MinION: 13:15–15:35Exporting samples means exporting opportunity: 15:35–18:40The sequencing workflow: 17:40–24:50Data processing: 24:50–27:45Using these technologies
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Neuropixels: big data heaven or burying the lead in averages?
18/01/2023 Duration: 19minIn this special episode of Talking techniques, one of two recorded at Neuroscience 2022, we speak to Tim Harris (Howard Hughes Medical Institute, VA, USA). Tim is the creator of Neuropixels, neural recording probes inserted into the brains of animal models, which allow researchers to collect signals from hundreds of individual neurons in different brain regions simultaneously over extended periods of time. Here, he shares the story behind his creation and details how they have changed the data collection landscape in Neuroscience. Tim also considers every inventor’s greatest concern: has his invention led to purely positive outcomes for the field? By enabling the collection of huge datasets have Neuropixels led to studies that bury findings in vast swathes of data or have they enabled researchers to collect enough information to discover the emphatic truth? Listen now to find out Tim’s opinions on these contentious debates in neuroscience and get key tips for utilizing neuropixels! Contents:Introduct
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Precision oncology: an interview with Karina Eterovic
05/01/2023 Duration: 12minIn this In the Zone podcast, we explore how precision oncology is currently utilized in the bioanalytical field, the use of liquid biopsies to support these studies and the major challenges impacting drug development.
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Why is personalised medicine vital to managing lung cancer?
08/12/2022 Duration: 07minHello and welcome to the latest episode of OC Talks, the podcast from Oncology Central. I am Jade Parker, Senior Editor of Oncology Central. Today I am joined by Laetitia Decroix Guilloux, Vice President of Oncology and EMEA Commercial Strategy Lead at Janssen, to discuss the patient journey through lung cancer, examine the lung cancer paradigm, and how the cancer research community can holistically address unmet needs in cancer.
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Tech Blast | CAR-T cell therapy development: from personalized to off the shelf approaches
07/12/2022 Duration: 18minIn this Tech blast episode, we talk CAR-T cell development for cancer immunotherapies with Ritwika Biswas, Product Scientist for Sino Biological. We cover some of the latest developments in the field, the advantages of CAR-T over other immunotherapies and selecting the perfect CAR-T antigen, amongst a whole host of different aspects in the field. Contents Introduction: 00:00-00:30 Core principles of cancer immunotherapy: 00:30-02:00 Explaining cancer immunity: 02:00-03:20 Distinguishing CAR-T from native T cells: 03:20-04:40 CAR-T antigen targets: 04:40-06:00 Techniques for engineering CAR-T cells: 06:00-08:00 Introducing off the shelf CAR-T cells: 08:00-09:45 Addressing challenges in off the shelf CAR-T: 09:45-11:30 Current status of CAR-T therapies: 11:30-12:55 Advantages of CAR-T cell therapy over other immunotherapies: 12:55-15:25 The future of CAR-T: 15:10-18:10
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OCTalks: monitoring MRD in hematological malignancy management
05/12/2022 Duration: 16minIn this interview we explore what minimal residual disease (MRD) is in hematological malignancies and how MRD is currently monitored. The interviewees also explain their recent research published in Nanomedicine, which investigates a novel tool to monitor hematological malignancies.
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Editor's Picks | November
25/11/2022 Duration: 05minThis month on Editor’s Picks, hear about the impacts of aerobic exercise on tumor microenvironments, the science behind female pleasure, how bacteria could be used to make whipped cream and the bacteria that could survive 280 million years on Mars!
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Daryl Cole Podcast Recording
18/11/2022 Duration: 08minIn this Tech Blast episode supported by Sartorius (Göttingen, Germany), we talk to Daryl Cole about cell line development (CLD), some of its challenges and a possible solution: the Octet Bio-Layer Interferometry (BLI) system. Daryl Cole is a Scientist in the Bio Applications Team at Sartorius with extensive experience in a range of fields; he offers insights into the possible applications of CLD and how to get the most out of the Octet BLI system.
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Editor's Picks | October
28/10/2022 Duration: 05minIn this episode of Editor’s Picks, we bring you the latest news in the life sciences including DishBrain, a dish of neurons that can play a computer game of table tennis, and click chemistry, which was awarded the Nobel Prize in Chemistry this year.