Synopsis
Periodic audiocasts from Science Signaling, the signal transduction knowledge environment.
Episodes
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Paper mills bribe editors to pass peer review, and detecting tumors with a blood draw
19/01/2024 Duration: 36minInvestigation shows journal editors getting paid to publish bunk papers, and new techniques for finding tumor DNA in the blood First up on this week’s episode, Frederik Joelving, an editor and reporter for the site Retraction Watch, talks with host Sarah Crespi about paper mills—organizations that sell authorship on research papers—that appear to be bribing journal editors to publish bogus articles. They talk about the drivers behind this activity and what publishers can do to stop it. Next, producer Zakiya Whatley of the Dope Labs podcast talks with researcher Carmen Martin-Alonso, a graduate student in the Harvard–Massachusetts Institute of Technology Program in Health Sciences and Technology, about improving liquid biopsies for cancer. They discuss novel ways to detect tumor DNA circulating in the blood. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi; Zakiya Whatley; Richard Stone Episode page: https://www.science.org/doi/10.1126/science
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The environmental toll of war in Ukraine, and communications between mom and fetus during childbirth
11/01/2024 Duration: 43minAssessing environmental damage during wartime, and tracking signaling between fetus and mother First up, freelance journalist Richard Stone returns with news from his latest trip to Ukraine. This week, he shares stories with host Sarah Crespi about environmental damage from the war, particularly the grave consequences of the Kakhovka Dam explosion. Next, producer Kevin McLean talks with researcher Nardhy Gomez-Lopez, a professor in the department of obstetrics and gynecology and pathology and immunology in the Center for Reproductive Health Sciences at Washington University School of Medicine in St. Louis. The two discuss signaling between fetus and mother during childbirth and how understanding this crosstalk may one day help predict premature labor. Finally, in a sponsored segment from the Science/AAAS Custom Publishing Office, Erika Berg, director and senior editor for the Custom Publishing Office, interviews Andrew Pospisilik, chair and professor of epigenetics at the Van Andel Institute, about his
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The top online news from 2023, and using cough sounds to diagnose disease
04/01/2024 Duration: 33minBest of online news, and screening for tuberculosis using sound This week’s episode starts out with a look back at the top 10 online news stories with Online News Editor David Grimm. There will be cat expressions and mad scientists, but also electric cement and mind reading. Read all top 10 here. Next on the show, can a machine distinguish a tuberculosis cough from other kinds of coughs? Manuja Sharma, who was a Ph.D. student in the department of electrical and computer engineering at the University of Washington at the time of the work, joins host Sarah Crespi to talk about her project collecting a cough data set to prove this kind of cough discrimination is possible with just a smartphone. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi; David Grimm Audio credit for human infant cries: Nicolas Grimault, Nicolas Mathevon, Florence Levréro; Neuroscience Research Center, ENES and CAP team. UJM, CNRS, France. Episode page: https://www.science
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The hunt for a quantum phantom, and making bitcoin legal tender
22/12/2023 Duration: 39minSeeking the Majorana fermion particle, and a look at El Salvador’s adoption of cryptocurrency First up on the show this week, freelance science journalist Zack Savitsky and host Sarah Crespi discuss the hunt for the elusive Majorana fermion particle, and why so many think it might be the best bet for a functional quantum computer. We also hear the mysterious tale of the disappearance of the particle’s namesake, Italian physicist Ettore Majorana. Next in the episode, what happens when you make a cryptocurrency legal tender? Diana Van Patten, professor of economics in the Yale University School of Management, discusses the results of El Salvador’s adoption of bitcoin in 2021. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi; Zack Savitsky Episode page: https://www.science.org/doi/10.1126/science.zjvhsy8 About the Science Podcast: https://www.science.org/content/page/about-science-podcast
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Science’s Breakthrough of the Year, and tracing poached pangolins
14/12/2023 Duration: 32minTop science from 2023, and a genetic tool for pangolin conservation First up this week, it’s Science’s Breakthrough of the Year with producer Meagan Cantwell and News Editor Greg Miller. But before they get to the tippy-top science find, a few of this year’s runners-up. See all our end-of-year coverage here. Next, Jen Tinsman, a forensic wildlife biologist at the U.S. Fish and Wildlife Service, joins host Sarah Crespi to discuss using genetics to track the illegal pangolin trade. These scaly little guys are the most trafficked mammals in the world, and researchers can now use DNA from their scales to find poaching hot spots. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi; Meagan Cantwell; Greg Miller Episode page: https://www.science.org/doi/10.1126/science.zk0pw91 About the Science Podcast: https://www.science.org/content/page/about-science-podcast
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Farm animals show their smarts, and how honeyguide birds lead humans to hives
07/12/2023 Duration: 38minA look at cognition in livestock, and the coevolution of wild bird–human cooperation This week we have two stories on thinking and learning in animals. First, Online News Editor David Grimm talks with host Sarah Crespi about a reporting trip to the Research Institute for Farm Animal Biology in northern Germany, where scientists are studying cognition in farm animals, including goats, cows, and pigs. And because freelance audio producer Kevin Caners went along, we have lots of sound from the trip—so prepare yourself for moos and more. Voices in this story: Christian Nawroth Annkatrin Pahl Jan Langbein Next, audio producer Katherine Irving talks with Claire Spottiswoode, an evolutionary biologist at the University of Cambridge, about her research into cooperation between honeyguide birds and human honey hunters. In their Science study, Spottiswoode and her team found honeyguides learn distinct signals made by honey hunters from different cultures suggesting that cultural coevolution has occurred. Read a
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Basic geoengineering, and autonomous construction robots
30/11/2023 Duration: 34minRaising the pH of the ocean to reduce carbon in the air, and robots that can landscape First up on this week’s show, Contributing Correspondent Warren Cornwall discusses research into making oceans more alkaline as a way to increase carbon capture and slow climate change. But there are a few open questions with this strategy: Could enough material be dumped in the ocean to slow climate change? Would mining that material release a lot of carbon? And, would either the mining or ocean changes have big impacts on ecosystems or human health? Next, we hear from Ryan Luke Johns, a recent Ph.D. graduate from ETH Zürich, about why we want robots building big rocky structures from found materials: It reduces energy costs and waste associated with construction, and it would allow us to build things remotely on Mars. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi; Warren Cornwall Episode page: https://www.science.org/doi/10.1126/science.z66mytn
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Exascale supercomputers amp up science, finally growing dolomite in the lab, and origins of patriarchy
23/11/2023 Duration: 54minA leap in supercomputing is a leap for science, cracking the dolomite problem, and a book on where patriarchy came from First up on this week’s show, bigger supercomputers help make superscience. Staff Writer Robert F. Service joins host Sarah Crespi to discuss how the first exascale computer is enabling big leaps in scientists’ models of the world. Next, producer Meagan Cantwell talks with the University of Michigan’s Wenhao Sun, professor of materials science and engineering, and graduate student Joonsoo Kim. They discuss solving the centuries-old problem of growing the common mineral dolomite in the lab. Finally, books host Angela Saini is back but this time she’s in the hot seat talking about her own book, The Patriarchs: The Origins of Inequality. Science Books Editor Valerie Thompson and host Sarah Crespi chat with Angela about what history, archaeology, and biology reveal about where and when patriarchy started. See our whole series of books podcasts on sex, gender, and science. This week’s epi
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AI improves weather prediction, and cutting emissions from landfills
16/11/2023 Duration: 21minWhat it means that artificial intelligence can now forecast the weather like a supercomputer, and measuring methane emissions from municipal waste First up on this week’s show, Staff Writer Paul Voosen joins host Sarah Crespi to talk about how artificial intelligence has become shockingly good at forecasting the weather while using way fewer resources than other modeling systems. Read a related Science paper. Next, focusing on municipal solid waste—landfills, compost centers, garbage dumps—may offer a potentially straightforward path to lower carbon emissions. Zheng Xuan Hoy, a recent graduate from the new energy science and engineering department at Xiamen University Malaysia, discusses his Science paper on this overlooked source of methane and some plausible solutions for reducing these emissions. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi; Paul Voosen Episode page: https://www.science.org/doi/10.1126/science.adm9783 Learn more about y
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The state of Russian science, and improving implantable bioelectronics
09/11/2023 Duration: 34minFirst up on this week’s show: the future of science in Russia. We hear about how the country’s scientists are split into two big groups: those that left Russia after the invasion of Ukraine and those that stayed behind. Freelance journalist Olga Dobrovidova talks with host Sarah Crespi about why so many have left, and the situation for those who remain. Next on the show: miniature, battery-free bioelectronics. Jacob Robinson, a professor in the department of electrical and computer engineering at Rice University, discusses how medical implants could go battery-free by harvesting energy from the human body and many other potential innovations in store for these internal medical devices. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi; Olga Dobrovidova LINKS FOR MP3 META Episode page: https://www.science.org/doi/10.1126/science.adm8195 About the Science Podcast: https://www.science.org/content/page/about-science-podcast
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Turning anemones into coral, and the future of psychiatric drugs
02/11/2023 Duration: 38minWhy scientists are trying to make anemones act like corals, and why it’s so hard to make pharmaceuticals for brain diseases First up on this week’s show, coaxing anemones to make rocks. Newsletter Editor Christie Wilcox joins host Sarah Crespi to discuss the difficulties of raising coral in the lab and a research group that’s instead trying to pin down the process of biomineralization by inserting coral genes into easy-to-maintain anemones. Next on the show, a look at why therapeutics for both neurodegenerative disease and psychiatric illness are lagging behind other kinds of medicines. Steve Hyman, director of the Stanley Center for Psychiatric Research at the Broad Institute, talks with Sarah about some of the stumbling blocks to developing drugs for the brain—including a lack of diverse genome sequences—and what researchers are doing to get things back on track. Finally, in a sponsored segment from the Science/AAAS Custom Publishing Office, associate editor Jackie Oberst discusses with Thomas Fuchs,
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Making corn shorter, and a book on finding India’s women in science
26/10/2023 Duration: 32minFirst up on this week’s show, Staff Writer Erik Stokstad joins host Sarah Crespi to talk about why it might make sense to grow shorter corn. It turns out the towering corn typically grown today is more likely to blow over in strong winds and can’t be planted very densely. Now, seedmakers are testing out new ways to make corn short through conventional breeding and transgenic techniques in the hopes of increasing yields. Next up on the show, the last in our series of books on sex and gender with Books Host Angela Saini. In this installment, Angela speaks with Nandita Jayaraj and Aashima Dogra about their book Lab Hopping: A Journey to Find India’s Women in Science. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi, Angela Saini, Erik Stokstad Episode page: https://www.science.org/doi/10.1126/science.adl5269
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The consequences of the world's largest dam removal, and building a quantum computer using sound waves
19/10/2023 Duration: 30minRestoring land after dam removal, and phonons as a basis for quantum computing First up on this week’s show, planting in the silty soil left behind after a dam is removed and reservoirs recede. Contributing Correspondent Warren Cornwall joins host Sarah Crespi to talk about the world's largest dam removal project and what ecologists are doing to revegetate 36 kilometers of new river edge. Next up on the show, freelance producer and former guest Tanya Roussy. She talks with Andrew Cleland, a professor at the University of Chicago, about a Science paper from this summer on using the phonon—a quantum of sound energy—as the basis of quantum computers. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi, Tanya Roussy, Warren Cornwall Episode page: https://www.science.org/doi/10.1126/science.adl4219
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Mysterious objects beyond Neptune, and how wildfire pollution behaves indoors
13/10/2023 Duration: 41minThe Kuiper belt might be bigger than we thought, and managing the effects of wildfires on indoor pollution First up on this week’s show, the Kuiper belt—the circular field of icy bodies, including Pluto, that surrounds our Solar System—might be bigger than we thought. Staff Writer Paul Voosen joins host Sarah Crespi to discuss the distant Kuiper belt objects out past Neptune, and how they were identified by telescopes looking for new targets for a visit by the New Horizons spacecraft. Next up on the show, the impact of wildfire smoke indoors. Producer Kevin McLean talks with Delphine Farmer, a chemist at Colorado State University, about an experiment to measure where particulates and volatile organic compounds end up when they sneak inside during a wildfire event. Finally, in a sponsored segment from the Science/AAAS Custom Publishing Office, Jackie Oberst, associate editor for custom publishing, discusses with Jens Nielsen, CEO of the BioInnovation Institute—an international life science incubator in C
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How long can ancient DNA survive, and how much stuff do we need to escape poverty?
05/10/2023 Duration: 35minPushing ancient DNA past the Pleistocene, and linking agriculture to biodiversity and infectious disease First up on this week’s show, Staff Writer Erik Stokstad brings a host of fascinating stories, from the arrival of deadly avian flu in the Galápagos to measuring the effect of earthworms on our daily bread. He and host Sarah Crespi start off the segment discussing just how much stuff you need to avoid abject poverty and why measuring this value can help us balance human needs against planetary sustainability. Other stories from Erik mentioned in this segment: ● Elephant trunk’s ‘stunning’ microscopic musculature may explain its dexterity | Science ● ‘Mind-boggling’ sea creature spotted off Japan has finally been identified | Science Next up on the show, as part of a special issue on ancient DNA, freelance producer Katherine Irving talks with Love Dalén, a professor of evolutionary genomics at the Centre for Palaeogenetics at Stockholm University. They talk about the longevity of ancient DNA
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Visiting utopias, fighting heat death, and making mysterious ‘dark earth’
28/09/2023 Duration: 50minA book on utopias and gender roles, India looks to beat climate-induced heat in cities, and how ancient Amazonians improved the soil First up on this week’s show: the latest in our series of books on sex, gender, and science. Books host Angela Saini discusses Everyday Utopia: In Praise of Radical Alternatives to the Traditional Family Home with ethnographer Kristen Ghodsee, professor of Russian and Eastern European studies at the University of Pennsylvania. See this year’s whole series here. Also this week, as part of a special issue on climate change and health, host Sarah Crespi speaks with Vaishnavi Chandrashekhar, a freelance journalist based in Mumbai, India. They talk about how India is looking to avoid overheating cities in the coming decades, as climate change and urbanization collide. Finally, we hear about how ancient Amazonians created fertile “dark earth” on purpose. Sarah is joined by Morgan Schmidt, an archaeologist and geographer at the Federal University of Santa Catarina. They discus
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Reducing cartel violence in Mexico, and what to read and see this fall
21/09/2023 Duration: 36minThe key to shrinking cartels is cutting recruitment, and a roundup of books, video games, movies, and more First up on this week’s show: modeling Mexico’s cartels. Rafael Prieto-Curiel, a postdoctoral research fellow at the Complexity Science Hub in Vienna, joins host Sarah Crespi to discuss how modeling cartel activities can help us understand the impact of potential interventions such as increased policing or reducing gang recruitment. Lisa Sanchez, executive director of México Unido Contra la Delincuencia, talks with Sarah about just how difficult it would be to make the model results—which show that reducing recruitment is key—a reality. Next on the show, Science books editor Valerie Thompson and books intern Jamie Dickman discuss a huge selection of science books, movies, video games, and even new exhibits—all due out this fall. See the complete roundup here. This week’s episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi, Valerie Thompson,
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Why cats love tuna, and powering robots with tiny explosions
14/09/2023 Duration: 33minReceptors that give our feline friends a craving for meat, and using combustion to propel insect-size robots First up on this week’s episode, Online News Editor David Grimm joins host Sarah Crespi to talk about why despite originating from a dry, desert environment cats seem to love to eat fish. Next on the show, bugs such as ants are tiny while at the same time fast and strong, and small robots can’t seem to match these insectile feats of speed and power. Cameron Aubin, a postdoc at Cornell University who will shortly join the University of Michigan, discusses using miniscule combustion reactions to bring small robots up to ant speed. Finally in a sponsored segment from the Science/AAAS Custom Publishing Office, Jackie Oberst, associate editor for custom publishing, discusses with Bobby Soni, chief business officer at the BioInnovation Institute, an international life science incubator in Copenhagen, Denmark, what it takes to bring a product from lab to market and how to make the leap from scient
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Extreme ocean currents from a volcano, and why it’s taking so long to wire green energy into the U.S. grid
07/09/2023 Duration: 33minHow the Tonga eruption caused some of the fastest underwater flows in history, and why many U.S. renewable energy projects are on hold First up on this week’s show, we hear about extremely fast underwater currents after a volcanic eruption. Producer Meagan Cantwell talks with sedimentary geologist Michael Clare and submarine volcanologist Isobel Yeo, both at the U.K. National Oceanography Centre. They discuss the complex aftermath of the Hunga Tonga-Hunga Ha’apai eruption, including fast and powerful ocean currents that severed seafloor cables. Watch a related video on last year’s eruption by Meagan: How the Tonga volcanic eruption rippled through the earth, ocean and atmosphere. Next on the show, an unexpected slowdown in connecting renewable power to the electrical grid. Freelance journalist Dan Charles joins host Sarah Crespi to discuss how problems with modeling energy flow in the electrical grid are holding up wind and solar power projects across the country. This week’s episode was
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Reducing calculus trauma, and teaching AI to smell
31/08/2023 Duration: 37minHow active learning improves calculus teaching, and using machine learning to map odors in the smell space First up on this week’s show, Laird Kramer, a professor of physics and faculty in the STEM Transformation Institute at Florida International University (FIU), talks with host Sarah Crespi about students leaving STEM fields because of calculus and his research into improving instruction. We also hear from some Science staffers about their own calculus trauma, from fear of spinning shapes to thinking twice about majoring in physics (featuring Kevin McLean, Paul Voosen, Lizzie Wade, Meagan Cantwell, and FIU student and learning assistant Carolyn Marquez). Next on the show, can a computer predict what something will smell like to a person by looking at its chemical structure? Emily Mayhew, a professor in the department of food science and human nutrition at Michigan State University, talks about how this was accomplished using a panel of trained smellers, and what the next steps are for digitizin