Synopsis
Periodic audiocasts from Science Signaling, the signal transduction knowledge environment.
Episodes
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An ancient empire hiding in plain sight, and the billion-dollar cost of illegal fishing
27/02/2020 Duration: 47minThis week on the podcast, Contributing Correspondent Lizzie Wade joins host Sarah Crespi to discuss a turning point for one ancient Mesoamerican city: Tikal. On 16 January 378 C.E., the Maya city lost its leader and the replacement may have been a stranger. We know from writings that the new leader wore the garb of another culture—the Teotihuacan—who lived in a giant city 1000 kilometers away. But was this new ruler of a Maya city really from a separate culture? New techniques being used at the Tikal and Teotihuacan sites have revealed conflicting evidence as to whether Teotihuacan really held sway over a much larger region than previously estimated. Sarah also talks with Rashid Sumaila, professor and Canada research chair in interdisciplinary ocean and fisheries economics at the University of British Columbia, Vancouver’s Institute for the Oceans and Fisheries. You may have heard of illegal fishing being bad for the environment or bad for maintaining fisheries—but as Sumaila and colleagues report this we
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Brickmaking bacteria and solar cells that turn ‘waste’ heat into electricity
20/02/2020 Duration: 33minOn this week’s show, staff writer Robert F. Service talks with host Sarah Crespi about manipulating microbes to make them produce building materials like bricks—and walls that can take toxins out of the air. Sarah also talks with Paul Davids, principal member of the technical staff in applied photonics & microsystems at Sandia National Laboratories, about an innovation in converting waste heat to electricity that uses similar materials to solar cells but depends on quantum tunneling. And in a bonus segment, producer Meagan Cantwell talks with online news editor David Grimm on stage at the AAAS annual meeting in Seattle. They discuss how wildfires can harm your lungs, crime rates in so-called sanctuary states, and how factors such as your gender and country of origin influence how much trust you put in science. This week’s episode was edited by Podigy. Listen to previous podcasts About the Science Podcast Download a transcript (PDF)
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NIH’s new diversity hiring program, and the role of memory suppression in resilience to trauma
13/02/2020 Duration: 26minOn this week’s show, senior correspondent Jeffrey Mervis joins host Sarah Crespi to discuss a new National Institutes of Health (NIH) grant program that aims to encourage diversity at the level of university faculty with the long-range goal of increasing the diversity of NIH-grant recipients. Sarah also talks with Pierre Gagnepain, a cognitive neuroscientist at INSERM, the French biomedical research agency, about the role of memory suppression in post-traumatic stress disorder. Could people that are better at suppressing memories be more resilient to the aftermath of trauma? This week’s episode was edited by Podigy. Listen to previous podcasts About the Science Podcast Download a transcript (PDF)
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Fighting cancer with CRISPR, and dating ancient rock art with wasp nests
06/02/2020 Duration: 27minOn this week’s show, Staff Writer Jennifer Couzin-Frankel joins host Sarah Crespi to talk about a Science paper that combines two hot areas of research-link—CRISPR gene editing and immunotherapy for cancer—and tests it in patients. Sarah also talks with Damien Finch, a Ph.D. candidate in the School of Earth Sciences at the University of Melbourne, about the Kimberly region of Australia and dating its ice age cave paintings using charcoal from nearby wasp nests. Episode page This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF).
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A cryo–electron microscope accessible to the masses, and tracing the genetics of schizophrenia
30/01/2020 Duration: 21minStructural biologists rejoiced when cryo–electron microscopy, a technique to generate highly detailed models of biomolecules, emerged. But years after its release, researchers still face long queues to access these machines. Science’s European News Editor Eric Hand walks host Meagan Cantwell through the journey of a group of researchers to create a cheaper, more accessible alternative. Also this week, host Joel Goldberg speaks with psychiatrist and researcher Goodman Sibeko, who worked with the Xhosa people of South Africa to help illuminate genetic details of schizophrenia. Though scientists have examined this subject among Western populations, much less is known about the underlying genetics of people native to Africa. This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast
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Getting BPA out of food containers, and tracing minute chemical mixtures in the environment
23/01/2020 Duration: 26minAs part of a special issue on chemicals for tomorrow’s Earth, we’ve got two green chemistry stories. First, host Sarah Crespi talks with contributing correspondent Warren Cornwell about how a company came up with a replacement for the popular can lining material bisphenol A and then recruited knowledgeable critics to test its safety. Sarah is also joined by Beate Escher of the Helmholtz Centre for Environmental Research and the University of Tübingen to discuss ways to trace complex mixtures of humanmade chemicals in the environment. They talk about how new technologies can help detect these mixtures, understand their toxicity, and eventually connect their effects on the environment, wildlife, and people. Read more in the special issue on chemicals for tomorrow’s Earth. This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF)
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Researchers flouting clinical reporting rules, and linking gut microbes to heart disease and diabetes
16/01/2020 Duration: 29minThough a U.S. law requiring clinical trial results reporting has been on the books for decades, many researchers have been slow to comply. Now, 2 years after the law was sharpened with higher penalties for noncompliance, investigative correspondent Charles Piller took a look at the results. He talks with host Sarah Crespi about the investigation and a surprising lack of compliance and enforcement. Also this week, Sarah talks with Brett Finlay, a microbiologist at the University Of British Columbia, Vancouver, about an Insight in this week’s issue that aims to connect the dots between noncommunicable diseases like heart disease, diabetes, and cancer and the microbes that live in our guts. Could these diseases actually spread through our microbiomes? This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: stu_spivack/Flickr; Music: Jeffrey Cook]
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Squeezing two people into an MRI machine, and deciding between what’s reasonable and what’s rational
09/01/2020 Duration: 21minGetting into a magnetic resonance imaging (MRI) machine can be a tight fit for just one person. Now, researchers interested in studying face-to-face interactions are attempting to squeeze a whole other person into the same tube, while taking functional MRI (fMRI) measurements. Staff news writer Kelly Servick joins host Sarah Crespi to talk about the kinds of questions simultaneous fMRIs might answer. Also this week, Sarah talks with Igor Grossman, the director of the Wisdom and Culture Lab at the University of Waterloo, about his group’s Science Advances paper on public perceptions of the difference between something being rational and something being reasonable. This week’s episode was edited by Podigy. Ads on this week’s show: KiwiCo Listen to previous podcasts About the Science Podcast [Image: Amanda/Flickr; Music: Jeffrey Cook] Authors: Kelly Servick, Sarah Crespi Transcript link: https://www.sciencemag.org/sites/default/files/SciencePodcast_200110.pdf
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Areas to watch in 2020, and how carnivorous plants evolved impressive traps
02/01/2020 Duration: 26minWe start our first episode of the new year looking at future trends in policy and research with host Joel Goldberg and several Science News writers. Jeffrey Mervis discusses upcoming policy changes, Kelly Servick gives a rundown of areas to watch in the life sciences, and Ann Gibbons talks about potential advances in ancient proteins and DNA. In research news, host Meagan Cantwell talks with Beatriz Pinto-Goncalves, a post-doctoral researcher at the John Innes Centre, about carnivorous plant traps. Through understanding the mechanisms that create these traps, Pinto-Goncalves and colleagues elucidate what this could mean for how they emerged in the evolutionary history of plants. This week’s episode was edited by Podigy. Ads on this week’s show: KiwiCo Listen to previous podcasts About the Science Podcast [Image: Eleanor/Flickr] ++ Authors: Joel Goldberg, Jeffrey Mervis, Kelly Servick, Ann Gibbons, Meagan Cantwell
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Breakthrough of the Year, our favorite online news stories, and the year in books
19/12/2019 Duration: 42minAs the year comes to a close, we review the best science, the best stories, and the best books from 2019. Our end-of-the-year episode kicks off with Host Sarah Crespi and Online News Editor David Grimm talking about the top online stories on things like human self-domestication, the “wood wide web,” and more. News Editor Tim Appenzeller joins Sarah to discuss Science’s 2019 Breakthrough of the Year, some of the contenders for breakthrough, also known as runners-up, and the breakdowns—when science and politics just didn’t seem to mix this year. Finally, Science books editor Valerie Thompson brings her favorites from the world of science-inflected media. She and Sarah talk about some of the best books reviewed in Science this year, a food extinction book we should have reviewed, a pair of science-centric films, and even an award-winning birding board game. For more science books, films, and games, visit the books et al blog at blogs.sciencemag.org/books. This week’s episode was edited by Podigy.
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Hunting for new epilepsy drugs, and capturing lightning from space
13/12/2019 Duration: 29minAbout one-third of people with epilepsy are treatment resistant. Up until now, epilepsy treatments have focused on taming seizures rather than the source of the disease and for good reason—so many roads lead to epilepsy: traumatic brain injury, extreme fever and infection, and genetic disorders, to name a few. Staff Writer Jennifer Couzin-Frankel talks with host Sarah Crespi about researchers that are turning back the pages on epilepsy, trying to get to the beginning of the story where new treatments might work. And Sarah also talks with Torsten Neurbert at the Technical University of Denmark’s National Space Institute in Kongens Lyngby about capturing high-altitude “transient luminous events” from the International Space Station (ISS). These lightning-induced bursts of light, color, and occasionally gamma rays were first reported in the 1990s but had only been recorded from the ground or aircraft. With new measurements from the ISS come new insights into the anatomy of lightning. This week’s episode
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Debating lab monkey retirement, and visiting a near-Earth asteroid
05/12/2019 Duration: 31minAfter their life as research subjects, what happens to lab monkeys? Some are euthanized to complete the research, others switch to new research projects, and some retire from lab life. Should they retire in place—in the same lab under the care of the same custodians—or should they be sent to retirement home–like sanctuaries? Online News Editor David Grimm joins host Sarah Crespi to discuss recently penned legislation that pushes for monkey retirements and a new collaboration between universities and sanctuaries to create a retirement pipeline for these primates. Sarah also talks with Dante Lauretta, principal investigator for NASA’s Origins, Spectral Interpretation, Resource Identification, Security, Regolith Explorer (OSIRIS-REx) and a professor at the University of Arizona in Tucson, about the latest news from the asteroid Bennu. Within 1 week of beginning its orbit of the asteroid, OSIRIS-REx was able to send back surprising images of the asteroid ejecting material. It’s extremely rocky surface also took
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Double dipping in an NIH loan repayment program, and using undersea cables as seismic sensors
28/11/2019 Duration: 39minThe National Institutes of Health’s largest loan repayment program was conceived to help scientists pay off school debts without relying on industry funding. But a close examination of the program by investigative correspondent Charles Piller has revealed that many participants are taking money from the government to repay their loans, while at the same time taking payments from pharmaceutical companies. Piller joins Host Sarah Crespi to talk about the steps he took to uncover this double dipping and why ethicists say this a conflict of interest. Sarah also talks with Nate Lindsey, a Ph.D. candidate at the University of California, Berkeley, about turning a 50-meter undersea fiber optic cable designed to move data into a sensor for activity in the ocean and the land underneath. During a 4-day test in Monterey Bay, California, the cable detected earthquakes, faults, waves, and even ocean-going storms. For this month’s books segment, Kiki Sandford talks with Dan Hooper about his book At the Edge of Time:
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Building a landslide observatory, and the universality of music
21/11/2019 Duration: 38minYou may have seen the aftermath of a landslide, driving along a twisty mountain road—a scattering of rocks and scree impinging on the pavement. And up until now, that’s pretty much how scientists have tracked landslides—roadside observations and spotty satellite images. Now, researchers are hoping to track landslides systematically by instrumenting an entire national park in Taiwan. The park is riddled with landslides—so much so that visitors wear helmets. Host Sarah Crespi talks with one of those visitors—freelance science journalist Katherine Kornei—about what we can learn from landslides. In a second rocking segment, Sarah also talks with Manvir Singh about the universality of music. His team asked the big questions in a Science paper out this week: Do all societies make music? What are the common elements that can be picked out from songs worldwide? Sarah and Manvir listen to songs and talk about what love ballads and lullabies have in common, regardless of their culture of origin. This week’s episode w
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How to make an Arctic ship ‘vanish,’ and how fast-moving spikes are heating the Sun’s atmosphere
14/11/2019 Duration: 25minThe Polarstern research vessel will spend 1 year locked in an Arctic ice floe. Aboard the ship and on the nearby ice, researchers will take measurements of the ice, air, water, and more in an effort to understand this pristine place. Science journalist Shannon Hall joins host Sarah Crespi to talk about her time aboard the Polarstern and how difficult these measurements are, when the researchers’ temporary Arctic home is the noisiest, smokiest, brightest thing around. After that icy start, Sarah talks also with Tanmoy Samanta, a postdoctoral researcher at Peking University in Beijing, about the source of the extreme temperature of the Sun’s corona, which can be up to 1 million K hotter than the surface of the Sun. His team’s careful measurements of spicules—small, plentiful, short-lived spikes of plasma that constantly ruffle the Sun’s surface—and the magnetic networks that seem to generate these spikes, suggest a solution to the long-standing problem of how spicules arise and, at the same time, their likely
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Unearthing slavery in the Caribbean, and the Catholic Church’s influence on modern psychology
07/11/2019 Duration: 29minMost historical accounts of slavery were written by colonists and planters. Researchers are now using the tools of archaeology to learn more about the day-to-day lives of enslaved Africans—how they survived the conditions of slavery, how they participated in local economies, and how they maintained their own agency. Host Sarah Crespi talks with Contributing Correspondent Lizzie Wade about a Caribbean archaeology project based on St. Croix in the U.S. Virgin Islands and launched by the founders of the Society for Black Archaeologists that aims to unearth these details. Watch a related video here. Sarah also talks with Jonathan Schulz, a professor in the Department of Economics at George Mason University in Fairfax, Virginia, about a role for the medieval Roman Catholic Church in so-called WEIRD psychology—western, educated, industrialized, rich, democratic. The bulk of psychology experiments have used participants that could be described as WEIRD, and according to many psychological measures, WEIRD subjects t
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How measles wipes out immune memory, and detecting small black holes
31/10/2019 Duration: 21minMeasles is a dangerous infection that can kill. As many as 100,000 people die from the disease each year. For those who survive infection, the virus leaves a lasting mark—it appears to wipe out the immune system’s memory. News Intern Eva Fredrick joins host Sarah Crespi to talk about a pair of studies that looked at how this happens in children’s immune systems. Read the related studies in Science and Science Immunology. In our second segment this week, Sarah talks with Todd Thompson, of Ohio State University in Columbus, about his effort to find a small black hole in a binary pair with a red giant star. Usually black holes are detected because they are accruing matter and as the matter interacts with the black hole, x-rays are released. Without this flashy signal, black hole detection gets much harder. Astronomers must look for the gravitational influence of the black holes on nearby stars—which is easier to spot when the black hole is massive. Thompson talks with Sarah about a new approach to finding smal
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A worldwide worm survey, and racial bias in a health care algorithm
24/10/2019 Duration: 41minEarthworms are easy … to find. But despite their prevalence and importance to ecosystems around the world, there hasn’t been a comprehensive survey of earthworm diversity or population size. This week in Science, Helen Philips, a postdoctoral fellow at the German Centre for Integrative Biodiversity Research and the Institute of Biology at Leipzig University, and colleagues published the results of their worldwide earthworm study, composed of data sets from many worm researchers around the globe. Host Sarah Crespi gets the lowdown from Philips on earthworm myths, collaborating with worm researchers, and links between worm populations and climate. Read a related commentary here. Sarah also talks with Ziad Obermeyer, a professor in the School of Public Health at the University of California, Berkeley, about dissecting out bias in an algorithm used by health care systems in the United States to recommend patients for additional health services. With unusual access to a proprietary algorithm, inputs, and outputs
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Trying to find the mind in the brain, and why adults are always criticizing ‘kids these days’
17/10/2019 Duration: 26minWe don’t know where consciousness comes from. And we don’t know whether animals have it, or whether we can detect it in patients in comas. Do neuroscientists even know where to look? A new competition aims to narrow down the bewildering number of theories of consciousness and get closer to finding its biological signs by pitting different theories against each other in experimental settings. Freelance journalist Sara Reardon talks with host Sarah Crespi about how the competition will work. In our second segment, we talk about how we think about children. For thousands of years, adults have complained about their lack of respect, intelligence, and tendency to distraction, compared with previous generations. A new study out this week in Science Advances suggests our own biased childhood memories might be at fault. Sarah Crespi talks with John Protzko of the University of California, Santa Barbara, about how terrible people thought kids were in 3800 B.C.E. and whether understanding those biases might change how
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Fossilized dinosaur proteins, and making a fridge from rubber bands
10/10/2019 Duration: 23minHave you ever tried to scrub off the dark, tarlike residue on a grill? That tough stuff is made up of polymers—basically just byproducts of cooking—and it is so persistent that researchers have found similar molecules that have survived hundreds of millions of years. And these aren’t from cook fires. They are actually the byproducts of death and fossilization. Host Sarah Crespi talks with Contributing Correspondent Gretchen Vogel about how these molecules can be found on the surface of certain fossils and used as fingerprints for the proteins that once dwelled in dinos. And Sarah talks with Zunfeng Liu, a professor at Nankai University in Tianjin, China, about a new cooling technology based on a 100-year-old observation that a stretched rubber band is warm and a relaxed one is cool. It’s going to be hard to beat the 60% efficiency of compression-based refrigerators and air conditioning units, but Zunfeng and colleagues aim to try, with twists and coils that can cool water by 7°C when relaxed. This week’s ep