Heart Matters

Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: Alan S. Brown, MD, FACC, FAHA, FNLA Both clinical trials for lowering Lp(a) had patients with established atherosclerotic cardiovascular disease (ASCVD). Join in for a further discussion on important updates presented at the 2023 National Lipid Association Meeting with Dr. Mary Katherine Cheeley and fellow ReachMD host, Dr. Alan Brown, Past President of the National Lipid Association.

Host: Javed Butler, MD Guest: John W. MacArthur With many barriers standing in the way of people in the United States who need a heart transplant, fewer than 10 percent of patients actually receive this life-saving surgery according to Stanford Medicine. Therefore, surgeons are working on different techniques to increase the pool of healthy donated hearts. To speak more about this, Dr. Javed Butler is joined by Dr. John MacArthur, Assistant Professor of Cardiothoracic Surgery at Stanford School of Medicine.

Host: Javed Butler, MD Guest: Pedro A Villablanca Spinetto, MD A complex condition known as tricuspid valve regurgitation may cause concern for patients as it typically doesn’t show signs or symptoms until the disease is severe. So what technologies and therapies do we have to look forward to? Join Dr. Javed Butler as he speaks with Dr. Pedro Villablanca, Structural Heart Interventional Cardiologist at Henry Ford Health.

Guest: Patricia A. Pellikka, M.D. Artificial intelligence (AI) has several applications in cardiology, such as echocardiography. Can machine learning and AI algorithms in echocardiology help clinicians better detect heart failure with preserved ejection fraction (HFpEF)? Dr. Patricia A. Pellikka, Director of the Ultrasound Research Center at the Mayo Clinic, shares data from ACC.23 and explores the potential of AI in detecting HFpEF.

Guest: Paul Sorajja, MD TRILUMINATE was the first trial to take a look at the impact of tricuspid regurgitation (TR) reduction on patients, and its results may lead to significant improvements in care and quality of life. To learn more about this trial, Dr. Paul Sorajja from the Minneapolis Heart Institute Foundation details the key findings from this trial and explores their impact.

Guest: Ana Barac, MD, PhD The American College of Cardiology's 72nd Scientific Session & Expo featured the latest advancements in all fields of cardiovascular medicine, including cardio-oncology. To learn more, Dr. Javed Butler sits down with Dr. Ana Barac from the MedStar Washington Hospital Center to take a look at clinical data from the STOP-CA trial.

Host: Marius M. Hoeper, MD A recent study explored the safety and efficacy of sotatercept on top of background pulmonary arterial hypertension (PAH) therapy. To learn more about this clinical data, Dr. Marius M. Hoeper, a Professor of Medicine and the Deputy Director of the Department of Respiratory Medicine at Hannover Medical School in Hannover, Germany, dives into the results of this trial and explores how they may impact patients with PAH.

Host: Javed Butler, MD Guest: Ana Barac, MD, PhD Cardio-oncology is a novel field in cardiovascular medicine that has rapidly grown over the past few years. What kind of role does multidisciplinary care have in it? Dr. Javed Butler is joined by Dr. Ana Barac from the Inova Heart and Vascular Institute to take a look at where cardio-oncology is and where it could be headed.

According to the CDC, patients with familial hypercholesterolemia or patients who show signs of coronary heart disease are at an increased chance of having heart attack, stroke, and aortic stenosis due to high levels of lipoprotein(a). So how can me manage lipoprotein(a) in our patients? To discuss this, Dr. Mary Katherine Cheeley is joined by fellow ReachMD host Dr. Alan Brown, who’s also the Director of the Division of Cardiology and the Lipid Clinic at Advocate Lutheran General Hospital.

Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: Kevin C. Maki, PhD, FNLA, CLS At the American College of Cardiology's 72nd Annual Scientific Session & Expo, cardiologists will gather to explore the latest advancements in the field. Joining us to share what you can expect to learn about statin intolerance at their upcoming session are Dr. Mary Katherine Cheeley and Dr. Kevin Maki.

Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: Laney K. Jones, PharmD, MPH Patients with familial hypercholesterolemia (FH) are at an increased risk of developing coronary heart disease at a young age. So what’s on the horizon for using implementation science strategies in treating patients with FH? Learn more about implementation science as Dr. Mary Katherine Cheeley discusses this with Dr. Laney Jones, Associate Professor at Geisinger’s Department of Genomic Health.

Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: Lauren Williams, MCN,RD,LD Kids with dyslipidemia don’t have much different nutritional needs than other young kids their age. However, there are a few key things to be aware of. So how can clinicians meet families where they are to improve their diet? Dive into the unique needs of youth with dyslipidemia as Dr. Mary Katherine Cheeley is joined by Lauren Williams, Class II Clinical Dietician at Cook Children’s Health System.

Host: Matthew Sorrentino, MD Guest: Luke Laffin, MD Six commonly used supplements thought to improve patients’ cholesterol may be doing more harm than good. So what do we need to know about these supplements? To walk us through the results of the SPORT trial, Dr. Matthew Sorrentino is joined by Dr. Luke Laffin, Co-Director of the Center for Blood Pressure Disorders at the Cleveland Clinic.

Host: Javed Butler, MD Guest: Scott Solomon, MD Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction (DELIVER trial) is a study designed to assess the effectiveness of SGLT2 inhibitors in patients with higher left ventricular ejection fraction. To help lead the discussion on the results of this study, Dr. Javed Butler is joined by Dr. Scott Solomon, lead study author and Director of the Clinical Trials Outcomes Center and the Edward D. Frohlich Distinguished Chair at Harvard Medical School.

Host: Matthew Sorrentino, MD Guest: Michael A. Solomon, MD, MBA Guest: Sean Agbor-Enoh, MD, PhD Pulmonary arterial hypertension (PAH) is a rare, and even fatal, condition that can impair the chest and lungs. But could a new blood test help us better assess disease severity and survivability in patients with PAH? To dive deeper into this topic, Dr. Matthew Sorrentino is joined by Dr. Michael Solomon and Dr. Sean Agbor-Enoh from the National Institutes of Health.

Host: Hector O. Chapa, MD, FACOG Guest: Erin Michos Polycystic ovary syndrome (PCOS) affects approximately 5 to 13 percent of women in the general population. And although previous research has shown its link to cardiovascular (CV) risk factors later in life, a new study has revealed that PCOS can increase the risk of heart complications during delivery. So what do these findings mean when it comes to caring for pregnant patients with PCOS? Find out with Dr. Hector Chapa as he’s joined by lead author of the study Dr. Erin Michos, who's the Director of Women’s Cardiovascular Health and an Associate Professor of Medicine at Johns Hopkins School of Medicine.

Host: Javed Butler, MD Guest: Sameed Khatana, MD, MPH As global temperatures continue to rise, experts are calling attention to the devastating effects this can have on human health. Cardiovascular mortality is especially a concern, as two recent studies from the University of Pennsylvania outlined the connection between these two health risks. To learn more about how climate change can impact our cardiovascular health, Dr. Javed Butler is joined by Dr. Sameed Khatana, Assistant Professor of Medicine at the Perelman School of Medicine at the University of Pennsylvania and a physician at the Philadelphia Veterans Affairs Medical Center.

Host: Javed Butler, MD Guest: Alice White, PhD Guest: Christopher Chen, MD, PhD There is currently no safe way to get a close-up view of the human heart, which is exactly why a team of Boston University researchers created a device to mimic the human organ. So how does the new device called miniPUMP work, and how was it developed? To discuss this, Dr. Javed Butler is joined by Dr. Alice White and Dr. Christopher Chen from Boston University.

Host: Javed Butler, MD Guest: Tariq Ahmad, MD, MPH The Pragmatic Trial of Messaging to Providers About Treatment in Heart Failure (PROMPT-HF) was designed to test the hypothesis that tailored and targeted electronic health record alerts recommending guideline-directed medical therapy (GDMT) for patients with heart failure (HF) would result in greater adherence to medication use. Explore the trial’s findings with Dr. Javed Butler and Dr. Tariq Ahmad, Director of the Heart Transplant and Mechanical Circulatory Support Program and Chief of Heart Failure at the Yale University School of Medicine.

Host: Javed Butler, MD Guest: Justin Ezekowitz, MD, MBBCh, MSc The Study of Dietary Intervention under 100 millimole in Heart Failure (SODIUM-HF) trial was designed to assess the effects of a low-sodium diet on adverse cardiovascular events. So what were the study’s findings, and what do they mean for our patients with heart failure? Dr. Javed Butler is joined by Dr. Justin Ezekowitz, who shared the SODIUM-HF trial results at the 2022 American of Cardiology Annual Scientific Meeting.