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Measurement of Thyroglobulin by Liquid Chromatography–Tandem Mass Spectrometry in Serum and Plasma in the Presence of Antithyroglobulin Autoantibodies

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Synopsis

Measurement of serum thyroglobulin may be complicated by the presence of endogenous anti-thyroglobulin auto-antibodies which have the potential to interfere with immunoassays and cause false negative results.