The Third Wave

Following our recent conversation with Dr. Robin Carhart-Harris on the neuroscience of SSRIs and psychedelics, this bonus episode takes the next step—focusing on clinical realities, tapering strategies, and patient safety. Find full show notes and links here: https://thethirdwave.co/podcast/episode-313b/?ref=278 Dr. Dave Rabin—a board-certified psychiatrist, neuroscientist, and co-founder of Apollo Neuro—joins Paul F. Austin for a candid, protocol-driven conversation. Together, they unpack why combining SSRIs with psychedelics can be dangerous, how to safely taper with support tools like ketamine and CBDA, and how to prepare clients for deeper psychedelic work. If you’re a facilitator, therapist, or simply someone navigating antidepressants and interested in microdosing, this episode offers practical, medically-grounded insights. Highlights: How SSRIs blunt emotional range and alter awareness The neuroscience of serotonin and psychedelic receptors Serious risks of serotonin syndrome when mixing with SSRIs Ke