The Holderness Family Podcast

There’s this phrase Penn and I say a lot when we’re overwhelmed making goofy internet videos—“It’s okay, we’re not saving lives.” But this week, we talk to a man who actually is saving lives and he needs us to help spread the word. Dr. David Fajgenbaum is the founder of Every Cure, a nonprofit that’s on a mission to do something that sounds impossible—use already-approved drugs to treat diseases they weren’t originally made for. Diagnosed with Castleman disease, Dr. David refused to accept that there was no cure. So, he saved his own life by repurposing existing medication and now he's on a mission to do the same for others.Using AI to search 75 million possible drug-disease combinations, they’re finding things to help with cancer and autism. They are all in clinical trials, but the results are promising. Because the medications are generic, there’s no big pharma marketing machine behind them. So they need our help to spread the word. Listen to the show where we hear more about Dr. David's story, his work, as