Science In Action

Back in November it was announced that an AI company called DeepMind had essentially cracked the problem of protein folding – that is they had managed to successfully predict the 3D structures of complex biochemical molecules by only knowing the 2D sequence of amino acids from which they are made.They are not the only team to use machine learning to approach the vast amounts of data involved. But last week, they released the source code and methodology behind their so called AlphaFold2 tool. Today, they are publishing via a paper in the journal Nature, a simply huge database of predicted structures including most of the human proteome and 20 other model species such as yes, mice. The possibilities for any biochemists are very exciting. As DeepMind CEO Demis Hassabis tells Roland Pease, they partnered with the European Molecular Biology Laboratory to make over 350,000 protein predictions available to researchers around the world free of charge and open sourced. Dr Benjamin Perry of the Drugs for Neglected Dise