Dr. Howard Smith Oncall

Moderna Vaccine Details

Informações:

Synopsis

  Vidcast:  https://youtu.be/gyHNlHNrOLc   From the actual documents the company submitted to the FDA and CDC.  The Moderna Vaccine consists of messenger RNA wrapped up in a lipid nanoparticle package.  The RNA is formulated to avoid immune destruction once injected and to code for a CoVid spike glycoprotein that will provoke production of a human antibody.  It is stored as a frozen suspension at -13 to 5 degrees Fahrenheit.   It is supplied in a 10 dose vial and is given as two 100 ug IM injections 28 days apart.   The vaccine does not contain eggs, preservatives, or latex.   It was first tested for safety and immunogenicity in a phase 1 trial of 120 persons and a fu phase 2 trial of 600 persons.  It’s effectiveness was confirmed and safety checked in a randomized blinded phase 3 trial involving 30,000 participants.     The results showed an ability to prevent any CoVid infection for all age patients of 94%, for those 18-64 yrs of 96%, and for those 65 and older of 86%.  No severe or fatal CoVid cases occurr