Dr. Howard Smith Oncall

Johnson & Johnson Vaccine Details

Informações:

Synopsis

  Vidcast:  https://youtu.be/iEqivMJb0ow   From the actual documents the company submitted to the FDA and CDC.  The J&J -Janssen Biotech vaccine is a vector vaccine employing a replication-incompetent human adenovirus Ad26 which has been modified to carry the DNA to encode for the CoVid spike proteins.  Once injected, the harmless virus enters human cells and triggers production of spike protein to which your body makes anti-CoVid antibodies and T killer cells.  The vaccine is stored as a refrigerated suspension at 36 to 46 degrees Fahrenheit.   It is supplied in a 5 dose vial and is given as ONE 0.5 ml IM injection containing 50 billion adenoviral particles.   The vaccine does not contain eggs or latex.   It was first tested for safety and immunogenicity in a phase 1 trial of 250 adults and a fu phase 1/2 trial of 1045 adults.  It’s effectiveness was confirmed and safety checked in a randomized blinded phase 3 trial involving 40,000 participants.  An additional phase 3 study is ongoing testing 2 doses of