Dr. Howard Smith Oncall

A Prototype Nanoparticle CoVid Vaccine Hits Variants

Informações:

Synopsis

  Vidcast:  https://youtu.be/Cy37zQuJfpA   A designer vaccine that presents mutated forms of Covid spike proteins to the immune system on nanoparticles induces powerful antibodies to the 3 current variants, the British B.1.1.7, the South African B.1.351, and the Brazilian P.1.  Immunologists at San Diego’s Scripps Institute now report this achievement as a promising solution to our current CoVid variant challenge.   Nanoparticle-mounted CoVid spike proteins more efficiently induce a broader range of virus killing antibodies compared with vaccines that present CoVid proteins in solution.  Why? Longer retention of the nanoparticle-bound antigens within lymph nodes and better presentation of the antigens to antibody-producing lymphocytes.   This technology is very welcome news.   https://www.biorxiv.org/content/10.1101/2021.03.26.437274v1.full.pdf+html   #CoVid #vaccine #nanotechnology #variants