Dr. Howard Smith Oncall

Nanoparticle Vaccine Immunizes Against All Variants

Informações:

Synopsis

  Vidcast:  https://youtu.be/R2F2OSytgGI   A new nanoparticle-based vaccine stimulates protective antibodies to the British, South African, and Brazilian variants in addition to the original Chinese CoVid.  Immunologists from San Diego’s Scripps Research Institute and Philadelphia’s Temple University now describe it on the pre-publication server biorixiv.org.   Their vaccine is a highly immunogenic version of mutated CoVid spike protein attached to nanoparticles.   Testing in mice shows it induces high titers of protective antibody because the nanoparticles assure the continued persistence of CoVid antigen in the lymph node factories that manufacture protective antibodies.   This technology can lead the way to more powerful vaccines that finally squelch CoVid and prevent its mutation to ever more dangerous variants.   https://www.biorxiv.org/content/10.1101/2021.03.26.437274v2.full.pdf+html     #CoVid #vaccine #nanoparticle #variants