Dr. Howard Smith Oncall

The Omicron BA.2 Subvariant Evades All Current Antibody Drugs

Informações:

Synopsis

  Vidcast:  https://youtu.be/YTKEt_tUi5c   The BA.2 subvariant of the Omicron variant has 6 additional mutations and 3 deletions that permit it to escape neutralization by the only two remaining monoclonal antibodies shown to capably neutralize the original Omicron subvariant,  Virologists at NYU report this finding after studying the neutralizing effects of various monoclonal antibodies and cocktail mixtures of them against native CoVid, the Delta variant, and the two sub variants of Omicron.   This new study shows that the two remaining drugs that showed neutralizing activities against Omicron1, Delta, and the original CoVid, Sotrovimab and the Evusheld antibody cocktail, fail to neutralize Omicron2.  Both the Regeneron and the Lilly antibody cocktails, effective against the original Covid virus and the Delta variant, show no useful neutralizing strength against either Omicron1 or Omicron2.   This is bad news for those who are looking to our current antiviral antibodies as medications for control of the dis