Dr. Howard Smith Oncall

mRNA Vaccine Effectiveness Against Omicron Subvariants

Informações:

Synopsis

  Vidcast:  https://youtu.be/-jApZNB4yAw   Just how effective are the Pfizer and Moderna vaccines for protection against the two Omicron subvariants BA.1 and BA.2?  The answer comes from a collaborative study from the epidemiologists at Cornell Medicine-Qatar following their study of 1,308,926 individuals who received the Pfizer and 894,142 who received the Moderna.   Of these groups, only 27% received the Pfizer booster and 16% received the Moderna booster.   Both mRNA CoVid vaccines were only about 45% protective against a symptomatic infection by either Omicron subvariant and only for about 3 months after the 2 dose vaccination.  It required a booster to maintain that protection longer-term.  Protection against a severe or deadly Omicron infection was 70-80% after the 2 dose vaccination longer-term but rose to more than 90-% after a booster.   In this first set of graphs, we can see that both Pfizer and Moderna vaccines worked about the same against OmicronBA1 and OmicronBA2.  The performance of the Modern