Bulletproof Radio

Is unlocking the full potential of your brain even possible, or just a myth from the movie Limitless? In this eye-opening episode, neuroscientist and author Dr. Mithu Storoni joins Dave to dive deep into the science of brain optimization for hyper-efficient work performance. Together, they break down the surprising roles of astrocytes in supporting neurons, the influence of the brain’s “blue dot” region (the locus coeruleus) on focus and mental clarity, and how harnessing neuroplasticity can lead to improved cognitive efficiency and resilience in high-stress environments. Get ready to discover actionable science-backed hacks for enhancing work productivity and maintaining focus—even in the face of constant distractions. Dr. Storoni also explains how optimizing your breathing rhythm, managing your brain’s arousal state, and tapping into the natural flow of ultradian rhythms can dramatically improve your mental output. Whether you’re looking to elevate your workflow, supercharge your mental perfo

What if the keys to an extraordinary life lie in choices most people wouldn’t dare to make? In this iconic, unearthed episode, best-selling author and performance pioneer Tim Ferriss joins Dave Asprey to spill the unfiltered truth on smart drugs, insect protein, and the surprising links between sex, creativity, and high performance. They dig into cutting-edge topics still sparking curiosity today: the calculated risks and rewards of smart drugs, the future-forward benefits of insect protein, and how unconventional habits fuel creativity and peak performance. Tim candidly shares his personal protocols, from routine blood testing to strategic supplementation, all rooted in his philosophy that “the dose makes the poison.” As a powerful wrap-up, Tim lays out his top three life principles for real success: choosing high-caliber people, focusing on those who “get it,” and setting audacious, even wild, goals. Whether you’re biohacking or simply intrigued, this episode delivers timeless insights and bo

What if everything you believe about happiness is wrong? In this episode, Harvard professor and world-renowned happiness expert Arthur Brooks joins Dave Asprey to unlock the secrets of real happiness, revealing the science behind joy, resilience, and lasting fulfillment. As a bestselling author and co-author with Oprah Winfrey of Build the Life You Want, Arthur has spent decades helping people rethink happiness through a blend of psychology, neuroscience, and ancient wisdom. Together, Dave and Arthur explore eye-opening topics like the “reverse bucket list,” why dopamine-driven goals often lead to disappointment, and how embracing discomfort can actually create deeper contentment. Arthur dives into why our common pursuits of fame, wealth, and success often fall short, and shares powerful strategies for mastering what’s within our control, building resilience, and finding meaning in life’s simplest moments. From managing dopamine to harnessing the power of small wins, this episode offers science

Explore the science and potential of hypnosis as Dr. David Spiegel, Stanford’s leading expert in mind-body medicine, joins Dave Asprey to reveal how hypnosis can radically enhance cognition, mental clarity, and resilience. In this episode of The Human Upgrade, you’ll learn how hypnosis influences the brain’s most vital networks, including the default mode network and executive control, to break mental barriers and amplify focus, perception, and healing. Discover how hypnosis, unlike traditional meditation or neurofeedback, accelerates response times, manages pain, and even helps alleviate PTSD. Dr. Spiegel shares stories of patients overcoming chronic pain and trauma through self-hypnosis, and details the mechanisms that make hypnosis a powerful tool for emotional and physical transformation. Dive into the fascinating brain science behind the practice, from theta brainwave induction to deep sensory modulation, and learn simple self-hypnosis techniques that can elevate mental performance, improve sle

Unlock the mastermind secrets to cognitive enhancement as Dave Asprey shares his ultimate brain-boosting biohacks in this powerful episode of The Human Upgrade. Discover how Dave elevated his IQ, reversed Asperger’s, and overcame brain fog through advanced neurofeedback, BDNF-boosting supplements, mitochondrial enhancers, and the power of the groundbreaking 40 Years of Zen program. Explore revolutionary techniques, from ancient meditation practices to modern nootropics and smart drugs, all designed to amplify memory, focus, and resilience. Learn the science behind cognitive enhancement, from ketones like C8 MCT oil to essential supplements like Vitamins D, K, A, and magnesium that fuel optimal brain function. If you’re seeking proven methods to enhance neuroplasticity, boost mental endurance, or reduce brain fog, this episode is packed with actionable insights. Whether you’re aiming to maximize mental performance or unlock the latest in brain science, Dave’s mastermind approach offers a comprehensiv

Unlock the secret to cellular detox and discover how to cleanse your body from the inside out with Dave Asprey and Jessica Berman in this episode of The Human Upgrade. Explore cutting-edge detox strategies using phosphatidylcholine, Tudca, and butyrate, three powerful molecules designed to remove toxins, microplastics, and endocrine disruptors from your system. Jessica, co-owner of BodyBio, reveals how these products support not just detoxification, but also optimize mitochondrial function, enhance brain performance, and improve overall cellular health. From phosphatidylcholine’s ability to restore cell membranes to Tudca’s role in liver health, you’ll learn how to protect yourself from the daily onslaught of environmental toxins that can harm your longevity and vitality. If you’ve been searching for how to reduce your toxic load, flush out microplastics, or boost cognitive function, this episode is packed with actionable insights. Whether you’re a biohacker looking to enhance your cellular resilien

Step into the future of sports performance with The Human Upgrade as Dave Asprey and Aron D’Souza, founder of the Enhanced Games, uncover the controversial world of steroids, gene therapy, peptides, and human enhancement. In this groundbreaking episode, they explore how athletes can push the boundaries of physical and mental performance by embracing cutting-edge science once banned by traditional sports bodies like the Olympics. Discover why the Enhanced Games are redefining fairness in athletics, allowing competitors to use biohacking and performance-enhancing technologies to unlock new levels of strength, speed, and recovery. Aron breaks down the ethical dilemmas, the science behind enhancements, and why athletes should have full control over their bodies and biology. From synthetic growth hormones to the latest in gene therapy, this episode dives deep into the future of sports innovation. Whether you’re fascinated by the world of biohacking, curious about the next big revolution in sports, or wan

Unlock the power of continuous glucose monitoring (CGM) and transform your health in this eye-opening episode with Dave Asprey. Discover why tracking your blood sugar 24/7 isn’t just for diabetics—it’s the key to unlocking peak health, optimizing your metabolism, and preventing chronic diseases. Joined by Levels founder and biohacker Josh Clemente, Dave dives into the real science behind CGMs and how they provide unparalleled insights into how your diet, sleep, and exercise affect your blood glucose. You’ll learn how glucose spikes are linked to aging, inflammation, and energy crashes, and why keeping your blood sugar stable can help you boost mental clarity, enhance longevity, and even prevent conditions like diabetes and heart disease. Josh reveals the engineering mindset behind building Levels and how this game-changing technology is revolutionizing the way we understand metabolic health. With insider data from 50,000+ users, you’ll discover how simple lifestyle tweaks—like post-meal walks, sleep

Get ready to discover the true superfoods that can transform your health—starting with spirulina and chlorella. In this dynamic and thought-provoking episode, Dave Asprey welcomes Catharine Arnston, founder of ENERGYbits, to dive deep into the world of algae and its incredible potential to boost energy, detox the body, and support longevity. First, we challenge the myths around trendy “superfoods” and reveal why algae, particularly spirulina and chlorella, reign supreme for mitochondrial health and cellular energy. Catharine shares her 15 years of research on algae, explaining how it protects your cells, enhances brain function, and even supports cancer prevention. Next, we explore cutting-edge science on how algae supercharge mitochondrial performance, with Catharine revealing new clinical trial data that shows a 20% boost in mitochondrial function in just seven days. Finally, we break down the real-life impacts—improved brainpower, glowing skin, and detoxified cells—showing how this powerhous

Today, we’re diving into the age old question, what is the purpose of your life? We chat about the science behind emotional intelligence with Dr. John Demartini, creator of the groundbreaking Demartini Method. In this thought-provoking episode, Dr. Demartini reveals how his unique approach to personal development and emotional mastery can help you uncover your highest values and transcend emotional chaos. We explore how the quality of the questions you ask shapes the quality of your life, providing a roadmap to unlock your fullest potential. First, we dig into the hidden order of the universe, showing how the Demartini Method guides you to balance emotion, intuition, and inspiration for greater control and fulfillment in life. Then, we break down Dr. Demartini’s journey—overcoming learning challenges, mastering the mind-body connection, and developing a method that has transformed lives around the globe. Finally, Dr. Demartini shares actionable strategies for tapping into your innate brill

Today, we’re unlocking the full potential of your brain—starting with Bryan Johnson’s Blueprint for longevity and brain optimization. We’re revisiting our conversation with Bryan, the creator of the Don’t Die movement (among many other things), to explore how his groundbreaking approach to brain health and biohacking is reshaping the future of longevity. First, we dive into Bryan’s mission to make brain monitoring as easy as tracking blood glucose, using his Blueprint protocol to measure and optimize cognitive performance for better health and wellness. Then, we tackle the deeper side of biohacking—longevity, societal reactions to living longer, and how to handle critics when you’re pushing the limits of human potential. Finally, Bryan shares his personal journey—investing $80M into brain science, building the Blueprint for optimal living, and discovering the power of community and lifelong friendships for a long, vibrant life. This episode will change the way you think about brain health

Today, we’re diving deep into biohacking your body’s performance—starting with your VO2 max and mitochondria. We’re sitting down with cellular optimization expert, Rowena Gates, to dive into how the NanoVi device is disrupting the world of biohacking, recovery, and training. First up, we’re breaking down VO2 max—the secret sauce to longevity. Forget endless hours of cardio. Learn how to hack your VO2 max efficiently and add years to your life, without grinding it out in the gym. Then, we tackle the hidden world of reactive oxygen species (ROS). These little molecules can be both your friend and foe—boosting energy or fast-tracking aging. We’ll show you how to control them, so you can keep your energy levels high and your body youthful. Finally, we explore the cutting-edge science of protein folding and exclusion zone water. Sound complicated? Don’t worry, we’ll break it down and show how NanoVi tech supercharges your mitochondria, giving you faster recovery and more endurance, all with min

Today, we’re hacking your home—big time. I’m sitting down with three experts who know exactly how your living space might be messing with your health, and more importantly, how to fix it. First up, we’ve got Michael Rubino, aka the mold medic, who’s here to blow your mind about the invisible toxins lurking in your walls. Mold? It’s everywhere, and it’s doing more damage than you think. Michael’s got killer insights on why dust might be your biggest health enemy and exactly how to get rid of it before it starts messing with your system. Then, we’ve got Ryan Blaser dropping some serious science on environmental toxins you probably didn’t even know were impacting you. EMFs? VOCs? Ryan explains why your home’s air quality might be worse than you think, and how to fix it with a few smart biohacks. Finally, Matteo Franceschetti, the sleep optimization guru, breaks down how your home could be trashing your sleep. He’s got the secrets to transforming your environment so you can supercharge your recover

What if you could control your brain’s performance and stress levels with just a few simple hacks? In this episode callback, Dave Asprey sits down with Dr. Andrew Huberman, a renowned neuroscientist from Stanford University, to unlock the secrets of how your brain really works—and how you can train it for enhanced cognitive power and stress resilience. From rewiring your brain’s fear response to mastering your level of alertness, Dr. Huberman reveals groundbreaking discoveries that could change the way you approach your mental and emotional well-being. Diving deep into neuroscience, they cover how visual stimuli can modulate stress, the role of autonomic arousal in cognitive performance, and even how brain-machine interfaces may soon push human potential beyond its current limits. You’ll learn why certain visual and sensory techniques can calm or excite your brain, and how to train your brain to handle high-stress situations with ease. Plus, find out how Dr. Huberman is working on curing blindness with V

Get ready to upgrade your cardiovascular health in a way you’ve never heard of before. Dave Asprey sits down with Dr. Michael Twyman, a pioneering biohacking cardiologist who blends cutting-edge functional medicine with conventional wisdom to help you avoid heart attacks and strokes. If you think cardiovascular disease is inevitable, think again. Dr. Twyman reveals the hidden mechanisms behind heart disease, starting with the misunderstood role of plaque in your arteries and the essential yet underappreciated glycocalyx—a slippery gel-like coating that could be the key to preventing arterial damage. From there, it’s all about prevention, prevention, prevention. Want to know how simple lifestyle tweaks can significantly reduce your risk of cardiovascular events? We’ve got the biohacks—grounding, sunlight exposure, cold plunges, and more—laid out for you in a step-by-step, easy-to-apply format. Dr. Twyman breaks down the crucial role of circadian biology and how aligning your body clock with natural light

Are you sleeping enough—or just enough to get by? In this episode of The Human Upgrade, Dave Asprey dives into the global sleep crisis and reveals why mastering your sleep is the most important biohack you can do for your health, performance, and longevity. This episode is your ultimate guide to transforming your rest and, by extension, your life. First, sleep scientist Matthew Walker breaks down how sleep deprivation has become a global epidemic, slashing up to 20% of our sleep in the past century. He unpacks the dangers of too little sleep, including its direct link to increased mortality rates and cognitive decline, and discusses the optimal sleep duration for both quantity and quality. Next, Peter Martone shifts the conversation to sleep posture and environment. He shares simple yet effective techniques for optimizing your sleep position to maximize deep, restorative rest. Learn how a small change in your pillow or bed setup can lead to dramatic improvements in your sleep quality and overall hea

Dave Asprey is joined again by glutathione expert Nayan Patel to explore the transformative effects of this “master antioxidant” glutaryl. From skin health and detoxification to energy production and mitochondrial function, glutathione plays a critical role in overall wellness. Nayan shares his cutting-edge research on topical glutathione delivery systems that are more effective than IV treatments and help combat oxidative stress. The conversation touches on innovative applications of glutathione for skin lightening (yes, including the surprising trend of butthole bleaching), the impact of environmental toxins, and how to optimize glutathione levels to support longevity and performance. Whether you’re battling oxidative stress, looking to rejuvenate your skin, or just curious about how glutathione can boost your health, this episode has something for everyone. Visit https://aurowellness.com/ and use code Dave10 to get 10% off your order!  Resources: Nayan Patel’s Bio: https://www.a4m.

In this transformative episode of The Human Upgrade, three of the world’s foremost experts on sexual wellness—Kim Anami, Susan Bratton, and Emily Morse—explore the depths of sexual mastery, pleasure, and performance. This discussion uncovers the often-overlooked power of sexual energy as a source of personal growth, healing, and vitality. Whether you’re looking to enhance your pleasure, improve your intimate relationships, or explore new dimensions of intimacy, this episode serves as your ultimate guide to unlocking the full potential of your sexual energy. Kim Anami delves into the profound ways sexual energy can be harnessed for personal transformation, teaching how to access life-changing orgasms and deeper intimacy. Susan Bratton brings her expertise to sexual biohacking and the latest technology that can enhance physical pleasure and performance. Emily Morse focuses on breaking down societal taboos around sex and providing actionable advice for better communication and connection with partners. 

In this episode of The Human Upgrade, Dave Asprey sits down with Clint Ober, the pioneer of grounding and earthing technology. Together, they explore the profound effects of reconnecting your body with the Earth’s natural energy through grounding, revealing how this practice can reduce inflammation, optimize mitochondrial function, and enhance overall well-being. Clint explains how he discovered the power of grounding during his career in the cable television industry and how it led him to study its benefits on human health. From studies showing improved cortisol levels and reduced inflammation to anecdotes about athletes using grounding for recovery, this episode delves into the science and personal experiences that highlight the effectiveness of earthing. Sponsors:  Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: Earthing Website: earthing.com Follow Clint Ober on I

In this episode of The Human Upgrade, we dive deep into the mystifying world of quantum energy with guest Philipp Samor von Holtzendorff-Fehling, founder of Leela Quantum Tech and Quantum Upgrade. Together with host Dave Asprey, Philipp unpacks the potential of harnessing quantum energy to enhance human performance, heal the body, and unlock higher consciousness.Philipp discusses how quantum energy has always existed and how modern technology now allows us to access and concentrate it like never before. From personal anecdotes involving quantum blocks to the exploration of biofields and how they influence everything from athletic performance to wound healing, this episode is packed with eye-opening insights.Dave shares his initial skepticism and eventual acceptance of quantum technology after experiencing the benefits firsthand. The conversation covers a range of fascinating topics including energy healing, distributed consciousness, quantum entanglement, and the ethics of working with energy fields. Plus, re